Lactate Dehydrogenase A/LDHA Antibody Blocking Peptide

Lactate dehydrogenase (LDH) is an ubiquitous enzyme commonly found in wide variety of organisms, including plants and microbes. LDH is involved in the interconversion of the pyruvate and NADH to lactate and NAD+. It is also called Hydroxybutyrate Dehydrogenase (HBD), due to the fact that it can catalyze the oxidation of hydroxybutyrate (1). In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C, forming various terameric isoenzymes (140 kDa). Lactate dehydrogenase A (LDH-A, muscle subunit, LDH-M) is involved in the final step of anaerobic glycoysis and catalyzes the conversion of L-lactate and NAD to pryruvate and NADH. While it is predominantly expressed in muscle tissue, it is hormonally regulated in rodents and overexpressed during mammary gland tumorigenesis (2). A mutation that cause deficiency in LDH-A has been implicated in exertional myoglobinuria (3).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

We have publications tested in 1 application: AC.

Showing Publications 1 - 2 of 2.

Publications using NBP1-48336PEP	Applications	Species
Marwarha G, Rosand O, Slagsvold KH, Hoydal MA GSK3 beta Inhibition Is the Molecular Pivot That Underlies the Mir-210-Induced Attenuation of Intrinsic Apoptosis Cascade during Hypoxia International journal of molecular sciences 2022-08-19 [PMID: 36012628] (AC)	AC
Marwarha G, Rosand o, Scrimgeour N et al. miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite Manner Biomedicines 2021-12-25 [PMID: 35052722]

Array NBP1-48336PEP

• Lactate Dehydrogenase A/LDHA Antibodies
• Lactate Dehydrogenase A/LDHA ELISA Kits
• Lactate Dehydrogenase A/LDHA Lysate
• Lactate Dehydrogenase A/LDHA Proteins
• Lactate Dehydrogenase A/LDHA Proteins and Enzyme