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KA2/GRIK5/Glutamate Receptor KA2 Antibody [Janelia Fluor® 646]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 646

Order Details

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KA2/GRIK5/Glutamate Receptor KA2 Antibody [Janelia Fluor® 646] Summary

Immunogen
Antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human Grik5. The immunogen is located within the last 50 amino acids of Grik5. Amino Acid Squence: EATSPPRPRPGPAGPRE
Specificity
This Grik5 antibody does not cross-react with Grik4.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GRIK5
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for KA2/GRIK5/Glutamate Receptor KA2 Antibody [Janelia Fluor® 646]

  • EAA2
  • Excitatory amino acid receptor 2
  • GluK5
  • glutamate receptor KA2
  • Glutamate receptor KA-2
  • glutamate receptor, ionotropic kainate 5
  • glutamate receptor, ionotropic, kainate 5
  • GRIK2
  • GRIK5
  • KA2/GRIK5
  • KA2GRIK2

Background

Glutamate receptor KA2 is a protein that interacts with glutamate, an excitatory neurotransmitter, in the central nervous system and that has two isoforms, measuring 980 and 981 amino acids in length, with weights of approximately 109 and 110 kDa respectively. Current studies are being done on diseases and disorders related to this protein including temporal lobe epilepsy, embryonal carcinoma, Parkinson's disease, schizophrenia, retinoblastoma, neruoblastoma, thyroiditis, and neuronitis. Glutamate receptor KA2 has also been shown to have interactions with GOLM1, GPAA1, LRSAM1, DLG4, and GRID2 in pathways such as the glutamic acid signaling, transmission across chemical synapses, and activation of kainite receptor pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GRIK5