Name: Integrin alpha V beta 5 Antibody (P5H9)
Brand: Novus Biologicals
SKU: MAB2528
Price: 449 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	Flow, IP, B/N, CyTOF-ready, ICC/IF
Clone	P5H9
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated
Concentration	LYOPH

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 FAB2528U-100UG

Alexa Fluor 405 FAB2528V-100UG

Alexa Fluor 488 FAB2528G-100UG

Alexa Fluor 532 FAB2528X

Alexa Fluor 594 FAB2528T-100UG

Alexa Fluor 647 FAB2528R-100UG

Alexa Fluor 700 FAB2528N-100UG

Alexa Fluor 750 FAB2528S-100UG

Allophycocyanin FAB2528A

Allophycocyanin/Cy7 FAB2528APCCY7

Biotin FAB2528B

CoraFluor 1 FAB2528CL1

DyLight 350 FAB2528D

DyLight 405 FAB2528E

DyLight 488 FAB2528K

DyLight 550 FAB2528L

DyLight 594 FAB2528M

DyLight 650 FAB2528W

DyLight 680 FAB2528Y

DyLight 755 FAB2528Z

FITC FAB2528F

HRP FAB2528H

Janelia Fluor 525 FAB2528JF525

Janelia Fluor 549 FAB2528I

Janelia Fluor 585 FAB2528JF585

Janelia Fluor 635 FAB2528JF635

Janelia Fluor 646 FAB2528J

Janelia Fluor 669 FAB2528JF669

PE/Atto594 FAB2528PEATT594

PE/Cy5.5 FAB2528PECY55

PE/Cy7 FAB2528PECY7

PerCP FAB2528C

Phycoerythrin FAB2528P

mFluor Violet 450 SE FAB2528MFV450

mFluor Violet 500 SE FAB2528MFV500

mFluor Violet 610 SE FAB2528MFV610

Catalog# & Formulation	Size	Price
Carrier Free FAB2528P

Carrier Free FAB2528A

Carrier Free MAB2528-SP

Carrier Free FAB2528V-100UG

Carrier Free FAB2528U-100UG

Carrier Free FAB2528T-100UG

Carrier Free FAB2528S-100UG

Carrier Free FAB2528R-100UG

Carrier Free FAB2528N-100UG

Carrier Free FAB2528G-100UG

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	FAB2528U-100UG
Alexa Fluor 405	FAB2528V-100UG
Alexa Fluor 488	FAB2528G-100UG
Alexa Fluor 532	FAB2528X
Alexa Fluor 594	FAB2528T-100UG
Alexa Fluor 647	FAB2528R-100UG
Alexa Fluor 700	FAB2528N-100UG
Alexa Fluor 750	FAB2528S-100UG
Allophycocyanin	FAB2528A
Allophycocyanin/Cy7	FAB2528APCCY7
Biotin	FAB2528B
CoraFluor 1	FAB2528CL1
DyLight 350	FAB2528D
DyLight 405	FAB2528E
DyLight 488	FAB2528K
DyLight 550	FAB2528L
DyLight 594	FAB2528M
DyLight 650	FAB2528W
DyLight 680	FAB2528Y
DyLight 755	FAB2528Z
FITC	FAB2528F
HRP	FAB2528H
Janelia Fluor 525	FAB2528JF525
Janelia Fluor 549	FAB2528I
Janelia Fluor 585	FAB2528JF585
Janelia Fluor 635	FAB2528JF635
Janelia Fluor 646	FAB2528J
Janelia Fluor 669	FAB2528JF669
PE/Atto594	FAB2528PEATT594
PE/Cy5.5	FAB2528PECY55
PE/Cy7	FAB2528PECY7
PerCP	FAB2528C
Phycoerythrin	FAB2528P
mFluor Violet 450 SE	FAB2528MFV450
mFluor Violet 500 SE	FAB2528MFV500
mFluor Violet 610 SE	FAB2528MFV610

Integrin alpha V beta 5 Antibody (P5H9)

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Integrin alpha V beta 5 Antibody (P5H9) Summary

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Publications for Integrin alpha V beta 5 Antibody (MAB2528)(19)

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Bioinformatics

Immunogen	HT1080 human fibrosarcoma cell line
Specificity	Detects human Integrin alpha V beta 5. Recognizes the human Integrin alpha V beta 5 heterodimer and does not recognize the alpha V subunit in association with any other beta subunits.
Source	N/A
Isotype	IgG1
Clonality	Monoclonal
Host	Mouse
Gene	ITGAV
Purity Statement	Protein A or G purified from hybridoma culture supernatant
Endotoxin Note	<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

Publications using MAB2528	Applications	Species
Makis Tzioras, Michael J.D. Daniels, Caitlin Davies, Paul Baxter, Declan King, Sean McKay et al. Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer’s disease via MFG-E8 Cell Reports Medicine 9/19/2023 [PMID: 37652017]
SI Gringhuis, TM Kaptein, EBM Remmerswaa, A Drewniak, BA Wevers, B Theelen, GRAM D'Haens, T Boekhout, TBH Geijtenbee Fungal sensing by dectin-1 directs the non-pathogenic polarization of TH17 cells through balanced type I IFN responses in human DCs Nature Immunology, 2022-12-01;0(0):. 2022-12-01 [PMID: 36456734] (Neutralization, Human)	Neutralization	Human
Neil Blanchard, Patrick A. Link, Daniela Farkas, Brennan Harmon, Jaylen Hudson, Srimathi Bogamuwa et al. Dichotomous role of integrin‐ beta 5 in lung endothelial cells Pulmonary Circulation 10/1/2022 [PMID: 36438452]
SM Shin, JS Kim, SW Park, SY Jun, HJ Kweon, DK Choi, D Lee, YB Cho, YS Kim Direct targeting of oncogenic RAS mutants with a tumor-specific cytosol-penetrating antibody inhibits RAS mutant-driven tumor growth Sci Adv, 2020-01-15;6(3):eaay2174. 2020-01-15 [PMID: 31998840] (Flow Cytometry, Human)	Flow Cytometry	Human
M Garcia-Mou, N Martinez-V, M Gonzalez-H, L Marrodán, M Cascallo, R Alemany, A Patiño-Gar, MM Alonso The oncolytic adenovirus VCN-01 promotes anti-tumor effect in primitive neuroectodermal tumor models Sci Rep, 2019-10-07;9(1):14368. 2019-10-07 [PMID: 31591461] (Flow Cytometry, Human)	Flow Cytometry	Human
E Peterman, P Gibieža, J Schafer, VA Skeberdis, A Kaupinis, M Valius, X Heiligenst, I Hurbain, G Raposo, R Prekeris The post-abscission midbody is an intracellular signaling organelle that regulates cell proliferation Nat Commun, 2019-07-18;10(1):3181. 2019-07-18 [PMID: 31320617] (ICC, Human)	ICC	Human
H Huang, Y Dong, Y Zhang, D Ru, Z Wu, J Zhang, M Shen, Y Duan, Y Sun GSH-sensitive Pt(IV) prodrug-loaded phase-transitional nanoparticles with a hybrid lipid-polymer shell for precise theranostics against ovarian cancer Theranostics, 2019-01-30;9(4):1047-1065. 2019-01-30 [PMID: 30867815] (Flow Cytometry, Human)	Flow Cytometry	Human
J Wei, A Marisetty, B Schrand, K Gabrusiewi, Y Hashimoto, M Ott, Z Grami, LY Kong, X Ling, HG Caruso, S Zhou, YA Wang, GN Fuller, JT Huse, E Gilboa, N Kang, X Huang, R Verhaak, S Li, AB Heimberger Osteopontin mediates glioblastoma-associated macrophage infiltration and is a therapeutic target J. Clin. Invest., 2018-11-19;0(0):. 2018-11-19 [PMID: 30307407] (Neutralization, Human)	Neutralization	Human
Stephanie R. Gillespie, Liana J. Tedesco, Lingyan Wang, Audrey M. Bernstein The deubiquitinase USP10 regulates integrin beta1 and beta5 and fibrotic wound healing Journal of Cell Science 10/15/2017 [PMID: 28851806]
K Miyano, H Cabral, Y Miura, Y Matsumoto, Y Mochida, H Kinoh, K Iwata, O Nagano, H Saya, N Nishiyama, K Kataoka, T Yamasoba cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells J Control Release, 2017-06-27;0(0):. 2017-06-27 [PMID: 28666729] (Flow Cytometry, Human)	Flow Cytometry	Human
ME Burgett, JD Lathia, P Roth, AS Nowacki, DS Galileo, E Pugacheva, P Huang, A Vasanji, M Li, T Byzova, T Mikkelsen, S Bao, JN Rich, M Weller, CL Gladson Direct contact with perivascular tumor cells enhances integrin ï¿½v?3 signaling and migration of endothelial cells Oncotarget, 2016-07-12;7(28):43852-43867. 2016-07-12 [PMID: 27270311] (Neutralization, Human)	Neutralization	Human
J-H Yun, S W Park, J H Kim, Y-J Park, C-H Cho, J H Kim Angiopoietin 2 induces astrocyte apoptosis via alpha v beta 5-integrin signaling in diabetic retinopathy Cell Death & Disease 2/18/2016 [PMID: 26890140]
Shen Y, Yang F, Wang H, Cai Z, Xu Y, Zhao A, Su Y, Zhang G, Zhu S Arg-Gly-Asp (RGD)-Modified E1A/E1B Double Mutant Adenovirus Enhances Antitumor Activity in Prostate Cancer Cells In Vitro and in Mice. PLoS ONE, 2016-01-22;11(1):e0147173. 2016-01-22 [PMID: 26799485] (Flow Cytometry, Human)	Flow Cytometry	Human
Dixon K, O'Flynn J, van der Kooij S, van Kooten C Phagocytosis of apoptotic or necrotic cells differentially regulates the transcriptional expression of IL-12 family members in dendritic cells. J Leukoc Biol, 2014-04-29;96(2):313-24. 2014-04-29 [PMID: 24782489] (Flow Cytometry, Human)	Flow Cytometry	Human
Mathieu M, Iampietro M, Chuchana P, Guerit D, Djouad F, Noel D, Jorgensen C Involvement of angiopoietin-like 4 in matrix remodeling during chondrogenic differentiation of mesenchymal stem cells. J Biol Chem, 2014-02-06;289(12):8402-12. 2014-02-06 [PMID: 24505142] (IHC, Neutralization, Human)	IHC, Neutralization	Human
Lingyan Wang, Christine M. Ly, Chun-Ying Ko, Erin E. Meyers, Daniel A. Lawrence, Audrey M. Bernstein uPA Binding to PAI-1 Induces Corneal Myofibroblast Differentiation on Vitronectin Investigative Opthalmology & Visual Science 7/13/2012 [PMID: 22700714]
Wang L, Pedroja BS, Meyers EE, Garcia AL, Twining SS, Bernstein AM Degradation of internalized alphaVbeta5 integrin is controlled by uPAR bound uPA: effect on beta1 integrin activity and alpha-SMA stress fiber assembly. PLoS ONE, 2012-03-21;7(3):e33915. 2012-03-21 [PMID: 22470492] (Neutralization, Human)	Neutralization	Human
Mingyi Wang, Zongming Fu, James Wu, Jing Zhang, Liqun Jiang, Benjamin Khazan et al. MFG-E8 activates proliferation of vascular smooth muscle cells via integrin signaling Aging Cell 6/1/2012 [PMID: 22385834]
Cabezon R, Sintes J, Llinas L, Benitez-Ribas D Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. Immunol. Lett., 2010-10-07;134(2):167-73. 2010-10-07 [PMID: 20933012] (Flow Cytometry, Human)	Flow Cytometry	Human
Show All 19 Publications. Collapse Publications.