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IL-5 Antibody (TRFK5) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications B/N, CyTOF-ready, ELISA, ELISA(Cap), ELISA(Det), Flow
Clone
TRFK5
Clonality
Monoclonal
Host
Rat
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC405U-100UG
Alexa Fluor 405
IC405V-100UG
Alexa Fluor 488
IC405G-100UG
Alexa Fluor 532
FAB405X
Alexa Fluor 594
IC405T-100UG
Alexa Fluor 647
IC405R-100UG
Alexa Fluor 700
IC405N-100UG
Alexa Fluor 750
IC405S-100UG
Allophycocyanin
FAB405A
Biotin
FAB405B
CoraFluor 1
FAB405CL1
DyLight 350
FAB405D
DyLight 405
FAB405E
DyLight 488
FAB405K
DyLight 550
FAB405L
DyLight 594
FAB405M
DyLight 650
FAB405W
DyLight 680
FAB405Y
DyLight 755
FAB405Z
FITC
FAB405F
HRP
FAB405H
Janelia Fluor 549
FAB405I
Janelia Fluor 585
FAB405JF585
Janelia Fluor 635
FAB405JF635
Janelia Fluor 646
FAB405J
Janelia Fluor 669
FAB405JF669
PE
FAB405P
PerCP
FAB405C
Unconjugated
MAB405-100
mFluor Violet 450 SE
FAB405MFV450
mFluor Violet 500 SE
FAB405MFV500
mFluor Violet 610 SE
FAB405MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB405-100
Carrier Free
MAB405-SP
Carrier Free
MAB405-100
Carrier Free
MAB405-500
Carrier Free
IC405V-100UG
Carrier Free
IC405U-100UG
Carrier Free
IC405T-100UG
Carrier Free
IC405S-100UG
Carrier Free
IC405R-100UG
Carrier Free
IC405N-100UG
Carrier Free
IC405G-100UG
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IL-5 Antibody (TRFK5) [Janelia Fluor® 525] Summary

Immunogen
Mouse T cell clone-derived partially purified recombinant mouse IL-5
Specificity
Detects human and mouse IL-5 in ELISAs. In sandwich immunoassays with BAM6051 as the detection antibody, no cross-reactivity with recombinant human (rh) IL-3, rhGM-CSF, or recombinant mouse (rm) IL-5 is observed. In sandwich ELISAs with BAM705 as the detection antibody, no cross-reactivity with rhIL-5, rmIL-3, or rmGM-CSF is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Rat
Gene
IL5
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-reported
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Intracellular Staining by Flow Cytometry
  • Neutralization
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for IL-5 Antibody (TRFK5) [Janelia Fluor® 525]

  • BCDF mu
  • B-cell differentiation factor I
  • BCGFII
  • EDF
  • Eo-CSF
  • Eosinophil differentiation factor
  • IL5
  • IL-5
  • IL-5T-cell replacing factor
  • interleukin 5 (colony-stimulating factor, eosinophil)
  • interleukin-5
  • TRF
  • TRFB cell differentiation factor I

Background

IL-5 (T cell replacing factor (TRF), eosinophil differentiation factor (EDF)) is a hematopoietic growth factor that stimulates the proliferation, differentiation and activation of eosinophils. It is produced by mast cells, T cells and eosinophils and has an important role in activating cell-mediated immunity following parasitic infections. It belongs to the same cytokine family as IL-3 and GM-CSF. The biologically active IL-5 consists of an antiparallel homodimer linked by disulfide bonds. Human and murine IL-5 are 70% identical at the amino acid level and show species cross-reactivity. IL-5 exerts its effects on target cells by binding to specific cell surface receptors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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IL-5 Antibody
(TRFK5) [Janelia Fluo ...
FAB405JF525
IL-5 Antibody (TRFK5) [Janelia Fluor® 525]
Species: Hu, Mu
Applications: B/N, CyTOF-ready, ELISA, ELISA(Cap), ELISA(Det), Flow

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol IL5