Home » IL-27R alpha/WSX-1/TCCR » IL-27R alpha/WSX-1/TCCR Antibodies » IL-27R alpha/WSX-1/TCCR Antibody (34N4G11) [CoraFluor™ 1]
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IL-27R alpha/WSX-1/TCCR Antibody (34N4G11) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, CyTOF-ready
Clone
34N4G11
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-19015AF350
Alexa Fluor 405
NBP2-19015AF405
Alexa Fluor 488
NBP2-19015AF488
Alexa Fluor 532
NBP2-19015AF532
Alexa Fluor 594
NBP2-19015AF594
Alexa Fluor 647
NBP2-19015AF647
Alexa Fluor 700
NBP2-19015AF700
Alexa Fluor 750
NBP2-19015AF750
Allophycocyanin
NBP2-19015APC
Allophycocyanin/Cy7
NBP2-19015APCCY7
Biotin
NBP2-19015B
DyLight 350
NBP2-19015UV
DyLight 405
NBP2-19015V
DyLight 488
NBP2-19015G
DyLight 550
NBP2-19015R
DyLight 594
NBP2-19015DL594
DyLight 650
NBP2-19015C
DyLight 680
NBP2-19015FR
DyLight 755
NBP2-19015IR
FITC
NBP2-19015F
HRP
NBP2-19015H
Janelia Fluor 525
NBP2-19015JF525
Janelia Fluor 549
NBP2-19015JF549
Janelia Fluor 646
NBP2-19015JF646
Janelia Fluor 669
NBP2-19015JF669
PE
NBP2-19015PE
PE/Atto594
NBP2-19015PEATT594
PE/Cy5.5
NBP2-19015PECY55
PE/Cy7
NBP2-19015PECY7
PerCP
NBP2-19015PCP
Unconjugated
NBP2-19015
mFluor Violet 450 SE
NBP2-19015MFV450
mFluor Violet 500 SE
NBP2-19015MFV500
mFluor Violet 610 SE
NBP2-19015MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-19015
BSA Free
NBP2-19015
BSA Free
NBP2-19015SS
Azide and BSA Free
NBP2-80807
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IL-27R alpha/WSX-1/TCCR Antibody (34N4G11) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
A portion of amino acids 200-250 of human IL-27R (WSX-1) was used as the immunogen for this antibody.
Specificity
IL-27R (WSX-1) is 65-70 kDa protein and is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes including CD4+ and CD8+ T cells, monocytes, DCs and NK cells
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
IL27RA
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow (Cell Surface)
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for IL-27R alpha/WSX-1/TCCR Antibody (34N4G11) [CoraFluor™ 1]

  • class I cytokine receptor
  • CRL1IL-27R
  • Cytokine receptor-like 1
  • IL-27 R alpha
  • IL27R alpha
  • IL27R
  • IL27RA
  • IL-27Ra
  • IL-27R-alpha
  • interleukin 27 receptor, alpha
  • interleukin-27 receptor subunit alpha
  • TCCR
  • TCCRIL-27 receptor subunit alpha
  • T-cell cytokine receptor type 1
  • Type I T-cell cytokine receptor
  • WSX-1
  • WSX1IL-27R subunit alpha
  • zcytor1

Background

Upon antigen challenge, T-helper cells differentiate into two functionally distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-g and lymphotoxin-b that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-g and Th1-dependent antibody IgG2a. TCCR is predominantly expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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IL-27R
alpha/WSX-1/TCCR Anti ...
NBP2-19015CL1
IL-27R alpha/WSX-1/TCCR Antibody (34N4G11) [CoraFluor™ 1]
Species: Hu
Applications: Flow, IHC, CyTOF-ready
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Bioinformatics

Gene Symbol IL27RA