Home » IL-17/IL-17A » IL-17/IL-17A Antibodies » IL-17/IL-17A Antibody (4k5F6) [DyLight 488]
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IL-17/IL-17A Antibody (4k5F6) [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Pm, Eq, Pm, Ma-OpSpecies Glossary
Applications WB
Clone
4k5F6
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-24765AF350
Alexa Fluor 405
NBP2-24765AF405
Alexa Fluor 488
NBP2-24765AF488
Alexa Fluor 532
NBP2-24765AF532
Alexa Fluor 594
NBP2-24765AF594
Alexa Fluor 647
NBP2-24765AF647
Alexa Fluor 700
NBP2-24765AF700
Alexa Fluor 750
NBP2-24765AF750
Biotin
NBP2-24765B
CoraFluor 1
NBP2-24765CL1
DyLight 350
NBP2-24765UV
DyLight 405
NBP2-24765V
DyLight 550
NBP2-24765R
DyLight 594
NBP2-24765DL594
DyLight 650
NBP2-24765C
DyLight 680
NBP2-24765FR
DyLight 755
NBP2-24765IR
FITC
NBP2-24765F
HRP
NBP2-24765H
Janelia Fluor 525
NBP2-24765JF525
Janelia Fluor 549
NBP2-24765JF549
Janelia Fluor 585
NBP2-24765JF585
Janelia Fluor 635
NBP2-24765JF635
Janelia Fluor 646
NBP2-24765JF646
Janelia Fluor 669
NBP2-24765JF669
Unconjugated
NBP2-24765
mFluor Violet 450 SE
NBP2-24765MFV450
mFluor Violet 500 SE
NBP2-24765MFV500
mFluor Violet 610 SE
NBP2-24765MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-24765
BSA Free
NBP2-24765
BSA Free
NBP2-24765SS
Azide and BSA Free
NBP2-46611
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IL-17/IL-17A Antibody (4k5F6) [DyLight 488] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
A synthetic peptide between amino acids 1-75 of human IL-17A was used as the immunogen for the antibody.
Predicted Species
Mouse (94%), Rat (94%), Equine (94%), Monkey (94%), Opossum (94%), Bovine (94%), Chimpanzee (94%). Backed by our 100% Guarantee.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
IL17A
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IL-17/IL-17A Antibody (4k5F6) [DyLight 488]

  • CTLA8
  • CTLA-8
  • CTLA8cytotoxic T-lymphocyte-associated serine esterase 8
  • Cytotoxic T-lymphocyte-associated antigen 8
  • IL17
  • IL-17
  • IL17A
  • IL-17A
  • IL-17Acytotoxic T-lymphocyte-associated protein 8
  • IL-17CTLA-8
  • IL17interleukin-17A
  • interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
  • interleukin 17A

Background

Interleukin 17 (IL-17) is a pro-inflammatory cytokine produced by TCRalpha/beta+ CD4 CD8 thymocytes, as well as by activated CD4+ and CD4+ CD45RO+ memory T cells (1). IL-17 stimulates the expression of TNFalpha, IL-1 beta, IL-6, and IL-8 (2). In addition, IL-17 is involved in the induction of inducible nitric oxide synthase and cyclooxygenase 2 in chondrocytes (3). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis (4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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IL-17/IL-17A
Antibody (4k5F6) [DyL ...
NBP2-24765G
IL-17/IL-17A Antibody (4k5F6) [DyLight 488]
Species: Hu, Mu, Rt, Bv, Pm, Eq, Pm, Ma-Op
Applications: WB

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for IL-17/IL-17A Antibody (NBP2-24765G). (Showing 1 - 2 of 2 FAQ).

  1. I want to stain some T cell subsets (Th17 and Th1), do you have antibodies for that? I need for flow cytometer in sheep or goat.
    • Unfortunately, we have neither a CD4 antibody nor an IL-17 antibody that has been validated in sheep or goat, although if you would like to try one you would again be eligible for our Innovators Reward Program. Please contact us at innovators@novusbio.com with any questions regarding this program.
  2. I'm looking to establish an ELISA for IL-17 and want your recommendation on which antibody pairs to buy. Least expensive ones, please. Also, I'd like the detection antibody to be fluorescently labeled.
    • Thank you for your patience while I reviewed our ELISA validated products for IL17. I was not sure what species you were going to be investigating, so I looked up our data for the human protein. If this is incorrect, just let me know and I can look up products for the species you will be working with. As for antibody pairs, we only had one set that have been tested together: Capture: NBP2-22531 Detection: NBP2-22532. The detection product is only available currently with a biotin conjugate. We can however offer custom conjugation for this product to any of our available conjugates. Please see the this link to see the available fluors. The typical fee for custom conjugation is usually about $80 additional. Once you know which fluor you would like, I can provide you with a quote. We do also offer several ELISA kits for this target (they typically employ HRP or Biotin detection systems, so I am not sure if they will work for your needs).

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL17A