IL-13R alpha 2 Antibody (83807)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Two type I membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with high affinity. The lower affinity IL-13 binding protein is now referred to as IL-13 R alpha 1 and is also known as CD213a. IL-13 R alpha 1 combines with IL-4 R alpha to form a high affinity receptor complex capable of transducing an IL-13-dependent proliferative signal. The higher affinity IL-13 binding protein, now referred to as IL-13 R alpha 2, does not induce a signal and acts as a decoy receptor (1, 2).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: ELISA Development, Flow Cytometry, IHC-P.

Showing Publications 1 - 2 of 2.

Publications using MAB6141	Applications	Species
Bellini A, Marini MA, Bianchetti L, Barczyk M, Schmidt M, Mattoli S Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients. Mucosal Immunol, 2011-12-21;5(2):140-9. 2011-12-21 [PMID: 22189956] (Flow Cytometry, Human)	Flow Cytometry	Human
Kioi M, Kawakami M, Shimamura T, Husain SR, Puri RK Interleukin-13 receptor alpha2 chain: a potential biomarker and molecular target for ovarian cancer therapy. Cancer, 2006-09-15;107(6):1407-18. 2006-09-15 [PMID: 16902988] (ELISA Development, IHC-P, Human)	ELISA Development, IHC-P	Human

Array MAB6141

• IL-13R alpha 2 Antibodies
• IL-13R alpha 2 ELISA Kits
• IL-13R alpha 2 Lysate
• IL-13R alpha 2 Proteins
• IL-13R alpha 2 Proteins and Enzymes
• IL-13R alpha 2 ELISAs