Human IL-1 alpha/IL-1F1 ELISA Kit (Colorimetric)

The interleukin-1 species represent an important family of biologically active mono nuclear cell-derived proteins which are involved in inflammatory reactions and in immune responses. Two distinct human IL-1 species, IL-1alpha and IL-1beta, have been identified. They share similarities such as the same molecular weight, similar biological effects and the same receptors on target cells. IL-1 proteins are produced by macrophages, monocytes and various other cell types such as adult T cell leukemias, fibroblasts, epithelial or endothelial cells, neutrophils and astrocytes. Their biological properties include pyrogenicity, bone resorption, presentation of antigen to T cells and stimulation of B and T lymphocyte proliferation. IL-1alpha is an extracellular peptide of 17 kDa, its activity has been demonstrated in various biological fluids including serum, synovial fluid, gingival fluid, amniotic fluid, sputum, cerebrosinal fluid, urine, and bronchoalveolar lavage (BAL) fluid. Elevated serum or blood levels of IL-1alpha have been found in patients with total hip replacement/ arthroplasties, in patients with recently diagnosted IDDM (Insulin-Dependent Diabetes Mellitus), in case of several carcinomas such as head and neck cancer, pancreatic cancer and thyroid cancer, in experimental acute pyelonephritis, in acute viral hepatitis and in septic shock.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

We have publications tested in 1 application: ELISA.

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Publication using NBP1-91187	Applications	Species
Chen YJ, Lin TL, Cai Z et al. Assessment of acute pancreatitis severity via determination of serum levels of hsa-miR-126-5p and IL-6 Experimental and Therapeutic Medicine 2020-11-09 [PMID: 33262812] (ELISA)	ELISA

Array NBP1-91187

• IL-1 alpha/IL-1F1 Antibodies
• IL-1 alpha/IL-1F1 Antibody Pair
• IL-1 alpha/IL-1F1 ELISA Kits
• IL-1 alpha/IL-1F1 Proteins
• IL-1 alpha/IL-1F1 ELISAs
• IL-1 alpha/IL-1F1 Proteins and Enzymes