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Recombinant Human IGFBP-5 Protein

Name: Recombinant Human IGFBP-5 Protein
Brand: Novus Biologicals
SKU: NBP2-61313
Price: 110 USD

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SDS-Page: Recombinant Human IGFBP-5 Protein [NBP2-61313]

Product Details

Summary

Reactivity	HuSpecies Glossary
Applications	Bioactivity
Concentration	LYOPH

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Recombinant Human IGFBP-5 Protein Summary

Description	A single non-glycosylated polypeptide chain containing 252 amino acids corresponding to IGFBP-5 Source: E. coli Uniprot ID: P24593 Amino Acid Sequence: LGSFVHCEPC DEKALSMCPP SPLGCELVKE PGCGCCMTCA LAEGQSCGVY TERCAQGLRC LPRQDEEKPL HALLHGRGVC LNEKSYREQV KIERDSREHE EPTTSEMAEE TYSPKIFRPK HTRISELKAE AVKKDRRKKL TQSKFVGGAE NTAHPRIISA PEMRQESEQG PCRRHMEASL QELKASPRMV PRAVYLPNCD RKGFYKRKQC KPSRGRKRGI CWCVDKYGMK LPGMEYVDGD FQCHTFDSSN VE
Details of Functionality	Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 cells is less than 0.4 ug/ml, corresponding to a specific activity of > 2500 IU/mg in the presence of 15 ng/ml of rHuIGF-II.
Source	E. coli
Protein/Peptide Type	Recombinant Protein
Gene	IGFBP5
Purity	>95%, by SDS-PAGE and HPLC
Endotoxin Note	Less than 0.1 EU/ug of IGFBP-5 as determined by LAL method.

Applications/Dilutions

Dilutions	Bioactivity
Theoretical MW	28.6 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage	Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.
Buffer	Lyophilized from a 0.2 um filtered concentrated solution in 10 mM Sodium Citrate, pH 3.0.
Preservative	No Preservative
Concentration	LYOPH
Purity	>95%, by SDS-PAGE and HPLC
Reconstitution Instructions	Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL.

Alternate Names for Recombinant Human IGFBP-5 Protein

IBP5IBP-5
IGF-binding protein 5
IGFBP5
IGFBP-5
insulin-like growth factor binding protein 5
insulin-like growth factor-binding protein 5

Background

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol

IGFBP5

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Recombinant Human IGFBP-5 Protein

Species Glossary

Images

Product Details

Order Details

Recombinant Human IGFBP-5 Protein Summary

Applications/Dilutions

Packaging, Storage & Formulations

Alternate Names for Recombinant Human IGFBP-5 Protein

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for IGFBP-5 Biologically Active Protein (NBP2-61313) (0)

Reviews for IGFBP-5 Biologically Active Protein (NBP2-61313) (0)

FAQs for IGFBP-5 Biologically Active Protein (NBP2-61313) (0)

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Bioinformatics