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IGF-I R/IGF1R Antibody [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Eq, Pm, BvSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-77680AF350
Alexa Fluor 405
NBP1-77680AF405
Alexa Fluor 488
NBP1-77680AF488
Alexa Fluor 532
NBP1-77680AF532
Alexa Fluor 594
NBP1-77680AF594
Alexa Fluor 647
NBP1-77680AF647
Alexa Fluor 700
NBP1-77680AF700
Alexa Fluor 750
NBP1-77680AF750
Allophycocyanin
NBP1-77680APC
Biotin
NBP1-77680B
CoraFluor 1
NBP1-77680CL1
DyLight 350
NBP1-77680UV
DyLight 405
NBP1-77680V
DyLight 550
NBP1-77680R
DyLight 594
NBP1-77680DL594
DyLight 650
NBP1-77680C
DyLight 680
NBP1-77680FR
DyLight 755
NBP1-77680IR
FITC
NBP1-77680F
HRP
NBP1-77680H
Janelia Fluor 525
NBP1-77680JF525
Janelia Fluor 549
NBP1-77680JF549
Janelia Fluor 585
NBP1-77680JF585
Janelia Fluor 635
NBP1-77680JF635
Janelia Fluor 646
NBP1-77680JF646
Janelia Fluor 669
NBP1-77680JF669
PE
NBP1-77680PE
PerCP
NBP1-77680PCP
Unconjugated
NBP1-77680
mFluor Violet 450 SE
NBP1-77680MFV450
mFluor Violet 500 SE
NBP1-77680MFV500
mFluor Violet 610 SE
NBP1-77680MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-77680
BSA Free
NBP1-77680SS
BSA Free
NBP1-77680
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IGF-I R/IGF1R Antibody [DyLight 488] Summary

Immunogen
A synthetic peptide made to an internal portion of the human IGF1 Receptor protein (between residues 700-800) [UniProt P08069]
Localization
Membrane.
Predicted Species
Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
IGF1R
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Reactivity with Equine reported via customer feedback. Predicted to react with Bovine (100%).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IGF-I R/IGF1R Antibody [DyLight 488]

  • CD221 antigen
  • CD221
  • EC 2.7.10
  • EC 2.7.10.1
  • IGF1R
  • IGF-1R
  • IGF-I R
  • IGF-I receptor
  • IGFIR
  • IGF-IR
  • IGFR
  • insulin-like growth factor 1 receptor
  • Insulin-like growth factor I receptor
  • JTK13
  • MGC142170
  • MGC142172
  • MGC18216
  • soluble IGF1R variant 1
  • soluble IGF1R variant 2

Background

Insulin-like growth factor receptor 1 (IGFR1) is a tyrosine kinase receptor that is important in embryonic development. IGFR1 has effects in breast, prostate, gastric and lung cancers, as it can be a player in drug resistance. It also affects the flow of nutrients from mother to placenta to fetus during development. IGFR1 seems to greatly influence the rate of growth of fetuses and newborn babies; when it is not appropriately expressed or regulated, fetal growth restriction occurs. The major activity of IGFR1 is to mediate the signaling of growth signals to effect downstream growth patterns.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Western Blot ERK2 Antibody [Unconjugated]
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Antibody [Unconjugate
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Antibody [Unconjugate
AF1067
Western Blot Growth Hormone Antibody [Unconjugated]
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AF578
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Species: Mu
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Secondary Antibodies

 

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Bioinformatics

Gene Symbol IGF1R