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IGF-I R/IGF1R Antibody [DyLight 350]

 
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Product Details

Summary
Reactivity Hu, Mu, Rt, PmSpecies Glossary
Applications WB, Simple Western, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 350

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-77679AF350
Alexa Fluor 405
NBP1-77679AF405
Alexa Fluor 488
NBP1-77679AF488
Alexa Fluor 532
NBP1-77679AF532
Alexa Fluor 594
NBP1-77679AF594
Alexa Fluor 647
NBP1-77679AF647
Alexa Fluor 700
NBP1-77679AF700
Alexa Fluor 750
NBP1-77679AF750
Allophycocyanin
NBP1-77679APC
Biotin
NBP1-77679B
CoraFluor 1
NBP1-77679CL1
DyLight 405
NBP1-77679V
DyLight 488
NBP1-77679G
DyLight 550
NBP1-77679R
DyLight 594
NBP1-77679DL594
DyLight 650
NBP1-77679C
DyLight 680
NBP1-77679FR
DyLight 755
NBP1-77679IR
FITC
NBP1-77679F
HRP
NBP1-77679H
Janelia Fluor 525
NBP1-77679JF525
Janelia Fluor 549
NBP1-77679JF549
Janelia Fluor 585
NBP1-77679JF585
Janelia Fluor 635
NBP1-77679JF635
Janelia Fluor 646
NBP1-77679JF646
Janelia Fluor 669
NBP1-77679JF669
PE
NBP1-77679PE
PerCP
NBP1-77679PCP
Unconjugated
NBP1-77679
mFluor Violet 450 SE
NBP1-77679MFV450
mFluor Violet 500 SE
NBP1-77679MFV500
mFluor Violet 610 SE
NBP1-77679MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-77679
BSA Free
NBP1-77679SS
BSA Free
NBP1-77679
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IGF-I R/IGF1R Antibody [DyLight 350] Summary

Immunogen
A synthetic peptide made to a C-terminal portion of the human IGF1 Receptor protein (between residues 1300-1367) [UniProt P08069].
Localization
Membrane.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
IGF1R
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IGF-I R/IGF1R Antibody [DyLight 350]

  • CD221 antigen
  • CD221
  • EC 2.7.10
  • EC 2.7.10.1
  • IGF1R
  • IGF-1R
  • IGF-I R
  • IGF-I receptor
  • IGFIR
  • IGF-IR
  • IGFR
  • insulin-like growth factor 1 receptor
  • Insulin-like growth factor I receptor
  • JTK13
  • MGC142170
  • MGC142172
  • MGC18216
  • soluble IGF1R variant 1
  • soluble IGF1R variant 2

Background

The IGF1 receptor prefers IGF1 over IGF2 and weakly binds insulin. IGF1 receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha (130 kD) and two beta (95 kD) subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The IGF1 receptor is therefore similar in structure to the insulin receptor. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The IGF1 receptor is highly expressed in all cell types and tissues and is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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DY871
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AF578
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Secondary Antibodies

 

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Bioinformatics

Gene Symbol IGF1R