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IGF-I R/IGF1R Antibody (33255) [Fluorescein]

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MCF-7 human breast cancer cell line was stained with Mouse Anti-Human IGF-I R Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB391F, filled histogram) or isotype control antibody (Catalog # IC002F, open histogram). View our protocol for Staining Membrane-associated Proteins.
MCF-7 human breast cancer cell line was stained with Mouse Anti-Human IGF-I R Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB391F, filled histogram) or isotype control antibody (Catalog # IC002F, open ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
33255
Clonality
Monoclonal
Host
Mouse
Conjugate
Fluorescein

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB391U-100UG
Alexa Fluor 405
FAB391V-100UG
Alexa Fluor 488
FAB391G-100UG
Alexa Fluor 532
FAB391X
Alexa Fluor 594
FAB391T-100UG
Alexa Fluor 647
FAB391R-100UG
Alexa Fluor 700
FAB391N-100UG
Alexa Fluor 750
FAB391S-100UG
Allophycocyanin
FAB391A
Allophycocyanin/Cy7
FAB391APCCY7
Biotin
FAB391B
CoraFluor 1
FAB391CL1
DyLight 350
FAB391D
DyLight 405
FAB391E
DyLight 488
FAB391K
DyLight 550
FAB391L
DyLight 594
FAB391M
DyLight 650
FAB391W
DyLight 680
FAB391Y
DyLight 755
FAB391Z
Fluorescein
FAB391F-025
HRP
FAB391H
Janelia Fluor 525
FAB391JF525
Janelia Fluor 549
FAB391I
Janelia Fluor 646
FAB391J
Janelia Fluor 669
FAB391JF669
PE/Atto594
FAB391PEATT594
PE/Cy5.5
FAB391PECY55
PE/Cy7
FAB391PECY7
Phycoerythrin
FAB391P-100
Phycoerythrin
FAB391P-025
Unconjugated
MAB391-100
mFluor Violet 450 SE
FAB391MFV450
mFluor Violet 500 SE
FAB391MFV500
mFluor Violet 610 SE
FAB391MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB391-100
Carrier Free
MAB391-SP
Carrier Free
FAB391F-025
Carrier Free
FAB391P-100
Carrier Free
FAB391P-025
Carrier Free
MAB391-100
Carrier Free
MAB391-500
Carrier Free
FAB391V-100UG
Carrier Free
FAB391U-100UG
Carrier Free
FAB391T-100UG
Carrier Free
FAB391S-100UG
Carrier Free
FAB391R-100UG
Carrier Free
FAB391N-100UG
Carrier Free
FAB391G-100UG
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IGF-I R/IGF1R Antibody (33255) [Fluorescein] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IGF-I R
Glu31-Asn932
Accession # P08069
Specificity
Detects human IGF-I R in sandwich immunoassays and Western blots. In sandwich immunoassays, less than 0.15% cross-reactivity or interference was observed with recombinant human (rh) IGF-I, rhIGF-II, rhIL-3 R alpha , rhIL-9 R, and rhTGF-beta  RII.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IGF1R
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB391F in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IGF-I R/IGF1R Antibody (33255) [Fluorescein]

  • CD221 antigen
  • CD221
  • EC 2.7.10
  • EC 2.7.10.1
  • IGF1R
  • IGF-1R
  • IGF-I R
  • IGF-I receptor
  • IGFIR
  • IGF-IR
  • IGFR
  • insulin-like growth factor 1 receptor
  • Insulin-like growth factor I receptor
  • JTK13
  • MGC142170
  • MGC142172
  • MGC18216
  • soluble IGF1R variant 1
  • soluble IGF1R variant 2

Background

Insulin-like Growth Factor I Receptor (IGF-I R) is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha and two beta subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The alpha subunit of IGF-I R is extracellular while the beta subunit has an extracellular domain, a transmembrane domain and a cytoplasmic tyrosine kinase domain. IGF-I R is highly expressed in all cell types and tissues. Essentially all of the biological activities of IGF-I and -II have been shown to be mediated via IGF-I R.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for IGF-I R/IGF1R Antibody (FAB391F)(3)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: Flow Cytometry, Flow Cytometry Control.


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(2)
Flow Cytometry Control
(1)
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(2)
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Bioinformatics

Gene Symbol IGF1R
Uniprot