Home » IGF-I R/IGF1R » IGF-I R/IGF1R Antibodies » IGF-I R/IGF1R Antibody (33255) [DyLight 550]
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IGF-I R/IGF1R Antibody (33255) [DyLight 550]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Flow, IHC, B/N, ELISA, ELISA(Cap), ELISA(Det), ICC/IF
Clone
33255
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB391U-100UG
Alexa Fluor 405
FAB391V-100UG
Alexa Fluor 488
FAB391G-100UG
Alexa Fluor 532
FAB391X
Alexa Fluor 594
FAB391T-100UG
Alexa Fluor 647
FAB391R-100UG
Alexa Fluor 700
FAB391N-100UG
Alexa Fluor 750
FAB391S-100UG
Allophycocyanin
FAB391A
Allophycocyanin/Cy7
FAB391APCCY7
Biotin
FAB391B
CoraFluor 1
FAB391CL1
DyLight 350
FAB391D
DyLight 405
FAB391E
DyLight 488
FAB391K
DyLight 594
FAB391M
DyLight 650
FAB391W
DyLight 680
FAB391Y
DyLight 755
FAB391Z
Fluorescein
FAB391F-025
Fluorescein
FAB391F-100
HRP
FAB391H
Janelia Fluor 525
FAB391JF525
Janelia Fluor 549
FAB391I
Janelia Fluor 585
FAB391JF585
Janelia Fluor 635
FAB391JF635
Janelia Fluor 646
FAB391J
Janelia Fluor 669
FAB391JF669
PE/Atto594
FAB391PEATT594
PE/Cy5.5
FAB391PECY55
PE/Cy7
FAB391PECY7
Phycoerythrin
FAB391P-025
Phycoerythrin
FAB391P-100
Unconjugated
MAB391-100
mFluor Violet 450 SE
FAB391MFV450
mFluor Violet 500 SE
FAB391MFV500
mFluor Violet 610 SE
FAB391MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB391-100
Carrier Free
MAB391-SP
Carrier Free
FAB391F-100
Carrier Free
FAB391F-025
Carrier Free
FAB391P-100
Carrier Free
FAB391P-025
Carrier Free
MAB391-100
Carrier Free
MAB391-500
Carrier Free
FAB391V-100UG
Carrier Free
FAB391U-100UG
Carrier Free
FAB391T-100UG
Carrier Free
FAB391S-100UG
Carrier Free
FAB391R-100UG
Carrier Free
FAB391N-100UG
Carrier Free
FAB391G-100UG
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IGF-I R/IGF1R Antibody (33255) [DyLight 550] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IGF-I R/IGF1R
Glu31-Asn932
Accession # P08069
Specificity
Detects human IGF-I R/IGF1R in sandwich ELISAs and Western blots. Detects mouse IGF-I R/IGF1R in Immunohistochemistry. In sandwich immunoassays, less than 0.15% cross-reactivity or interference was observed with recombinant human (rh) IGF-I, rhIGF‑II, rhIL‑3 R alpha , rhIL‑9 R, and rhTGF‑ beta  RII.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IGF1R
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Flow Cytometry
  • Immunocytochemistry
  • Immunohistochemistry
  • Neutralization
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IGF-I R/IGF1R Antibody (33255) [DyLight 550]

  • CD221 antigen
  • CD221
  • EC 2.7.10
  • EC 2.7.10.1
  • IGF1R
  • IGF-1R
  • IGF-I R
  • IGF-I receptor
  • IGFIR
  • IGF-IR
  • IGFR
  • insulin-like growth factor 1 receptor
  • Insulin-like growth factor I receptor
  • JTK13
  • MGC142170
  • MGC142172
  • MGC18216
  • soluble IGF1R variant 1
  • soluble IGF1R variant 2

Background

The IGF1 receptor prefers IGF1 over IGF2 and weakly binds insulin. IGF1 receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha (130 kD) and two beta (95 kD) subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The IGF1 receptor is therefore similar in structure to the insulin receptor. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The IGF1 receptor is highly expressed in all cell types and tissues and is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IGF1R