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IGF-I/IGF-1 Antibody (IGF1/2872R) [HRP]

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Product Details

Summary
Reactivity Hu, Mu, Rt, RbSpecies Glossary
Applications ELISA, Flow, ICC/IF
Clone
IGF1/2872R
Clonality
Monoclonal
Host
Rabbit
Conjugate
HRP

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-08416AF350
Alexa Fluor 405
NBP3-08416AF405
Alexa Fluor 488
NBP3-08416AF488
Alexa Fluor 532
NBP3-08416AF532
Alexa Fluor 594
NBP3-08416AF594
Alexa Fluor 647
NBP3-08416AF647
Alexa Fluor 700
NBP3-08416AF700
Alexa Fluor 750
NBP3-08416AF750
Allophycocyanin
NBP3-08416APC
Biotin
NBP3-08416B
DyLight 350
NBP3-08416UV
DyLight 405
NBP3-08416V
DyLight 488
NBP3-08416G
DyLight 550
NBP3-08416R
DyLight 594
NBP3-08416DL594
DyLight 650
NBP3-08416C
DyLight 680
NBP3-08416FR
DyLight 755
NBP3-08416IR
FITC
NBP3-08416F
Janelia Fluor 549
NBP3-08416JF549
Janelia Fluor 646
NBP3-08416JF646
PE
NBP3-08416PE
PerCP
NBP3-08416PCP
Unconjugated
NBP3-07381-100ug
mFluor Violet 450 SE
NBP3-08416MFV450
mFluor Violet 500 SE
NBP3-08416MFV500
mFluor Violet 610 SE
NBP3-08416MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-07381-100ug
Azide and BSA Free
NBP3-08416
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IGF-I/IGF-1 Antibody (IGF1/2872R) [HRP] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant full-length human IGF-I/IGF-1 protein (Uniprot: P05019)
Localization
Cytoplasmic (Secreted)
Specificity
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
IGF1
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Alternate Names for IGF-I/IGF-1 Antibody (IGF1/2872R) [HRP]

  • IBP1
  • IGF1
  • IGF-1
  • IGF1A
  • IGFI
  • IGF-I
  • IGF-IA
  • IGF-IB
  • insulin-like growth factor 1 (somatomedin C)
  • insulin-like growth factor 1
  • insulin-like growth factor I
  • insulin-like growth factor IA
  • insulin-like growth factor IB
  • Mechano growth factor
  • MGF
  • Somatomedin A
  • Somatomedin C
  • somatomedin-C

Background

Insulin is a pancreatic hormone that regulates glucose uptake and the synthesis of protein and fat. The insulin like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth promoting activity. IGF1 (Insulin Like Growth Factor I) is a polypeptide growth factor, which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. IGF1 functions as an autocrine regulator of growth.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol IGF1