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IFN-beta Antibody (RMMB-1) [Unconjugated]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Clone
RMMB-1
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated

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IFN-beta Antibody (RMMB-1) [Unconjugated] Summary

Immunogen
Human interferon beta
Specificity
Weakly neutralizes mouse interferon beta, but not recommended for neutralization assays; binds to mouse interferon beta
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
IFNB1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Direct ELISA
Publications
Read Publications using
22400-1 in the following applications:

Packaging, Storage & Formulations

Storage
After receipt, the product may be stored at -20°C for short-term use (≤ 6 months). For
long-term storage, we recommend storing the product at -70°C or below for retention of full activity. When thawing, the
contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum.
Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers
containing protein such as 0.1% bovine serum albumin (BSA).
Buffer
Phosphate buffered saline (PBS) containing 0.1% bovine serum albumin (BSA)
Preservative
No Preservative

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IFN-beta Antibody (RMMB-1) [Unconjugated]

  • Fibroblast interferon
  • IFB
  • IFBIFNB
  • IFF
  • IFNB
  • IFNB1
  • IFNbeta
  • IFN-beta
  • interferon beta
  • interferon, beta 1, fibroblast
  • MGC96956

Background

Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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IFN-beta Antibody
(RMMB-1) [Unconjugate ...
22400-1
IFN-beta Antibody (RMMB-1) [Unconjugated]
Species: Mu
Applications: ELISA

Publications for IFN-beta Antibody (22400-1)(4)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 2 applications: ELISA Development, Neutralization.


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ELISA Development
(2)
Neutralization
(2)
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Mouse
(4)
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FAQs for IFN-beta Antibody (22400-1) (0)

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Bioinformatics

Gene Symbol IFNB1