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IA-2/PTPRN Antibody - BSA Free

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Immunohistochemistry-Paraffin: IA-2/PTPRN Antibody [NBP1-83128] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry: IA-2/PTPRN Antibody [NBP1-83128] - Staining of human adrenal gland shows high expression.
Immunohistochemistry-Paraffin: IA-2/PTPRN Antibody [NBP1-83128] - Staining of human adrenal gland shows strong cytoplasmic positivity in medullary cells.
Orthogonal Strategies: Immunohistochemistry-Paraffin: IA-2/PTPRN Antibody [NBP1-83128] - Staining in human adrenal gland and skeletal muscle tissues using anti-PTPRN antibody. Corresponding PTPRN RNA-seq data are ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Validated by:
       

Orthogonal Strategies

 

Order Details

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Catalog# & Formulation Size Price

IA-2/PTPRN Antibody - BSA Free Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: HSYGDLPGPSPAQLFQDSGLLYLAQELPAPSRARVPRLPEQGSSSRAEDSPEGYEKEGLGDRGEKPASPAVQPDAALQRLAAVLAGYGVELRQLTPEQLSTLLTLLQLLPKGA
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PTPRN
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
IA-2/PTPRN Protein (NBP1-83128PEP)
Publications
Read Publication using NBP1-83128.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (81%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for IA-2/PTPRN Antibody - BSA Free

  • CA 512
  • EC 3.1.3.48
  • FLJ16131
  • IA2
  • IA-2
  • IA-2/PTP
  • ICA 512
  • ICA3
  • ICA512
  • islet cell antigen 2
  • Islet cell antigen 512
  • Islet cell autoantigen 3
  • protein tyrosine phosphatase, receptor type, N
  • protein tyrosine phosphatase-like N
  • PTP IA-2
  • PTPRN
  • receptor-type tyrosine-protein phosphatase-like N
  • R-PTP-N

Background

PTPRN is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for IA-2/PTPRN Antibody (NBP1-83128)(1)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PTPRN