IA-2/PTPRN Products

Description

PTPRN is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. [provided by RefSeq]

Bioinformatics

Entrez	116660 Rat 19275 Mouse 5798 Human
Uniprot	AAH07713 Human AAH70053 Human AAH70053.1 Human NP_002837 Human NP_002837.1 Human Q16849 Human Q7KZS4 Human
Product By Gene ID	5798
Alternate Names	CA 512 EC 3.1.3.48 FLJ16131 IA2 IA-2 IA-2/PTP ICA 512 ICA3 ICA512 islet cell antigen 2 Islet cell antigen 512 Islet cell autoantigen 3 protein tyrosine phosphatase, receptor type, N protein tyrosine phosphatase-like N PTP IA-2 receptor-type tyrosine-protein phosphatase-like N R-PTP-N

Research Areas for IA-2/PTPRN

Find related products by research area and learn more about each of the different research areas below.

Immune System Diseases
Immunology
Lipid and Metabolism