Human IL-5 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

IL-5 (Interleukin-5) is a secreted cytokine that is expressed as a covalent dimer. It is produced by activated Th2 cells, eosinophils, mast cells, and iNKT cells and promotes eosinophilic and basophilic differentiation and activation. IL-5 signals through a receptor complex containing IL-5 R alpha and the Common beta Chain/CD131 on eosinophils and basophils. Naturally occurring soluble forms of IL-5 R alpha retain the ability to bind IL-5 and limit its bioavailability.

We have publications tested in 2 confirmed species: Human, Mouse.

Showing Publications 1 - 10 of 26. Show All 26 Publications. Collapse Publications.

Publications using DY205	Applications	Species
Katsoulis, O;Toussaint, M;Jackson, MM;Mallia, P;Footitt, J;Mincham, KT;Meyer, GFM;Kebadze, T;Gilmour, A;Long, M;Aswani, AD;Snelgrove, RJ;Johnston, SL;Chalmers, JD;Singanayagam, A; Neutrophil extracellular traps promote immunopathogenesis of virus-induced COPD exacerbations Nature communications 2024-07-09 [PMID: 38982052] (Human)		Human
da Costa Teixeira, LA;Soares, LA;Lima, LP;Avelar, NCP;de Moura, JA;Leopoldino, AAO;Figueiredo, PHS;Parentoni, AN;Mendonça, VA;Lacerda, ACR; Cognitive function is associated with performance in time up and go test and with leptin blood levels in community-dwelling older women Scientific reports 2024-04-29 [PMID: 38684691] (Human)		Human
Augusto da Costa Teixeira, L;Rocha-Vieira, E;Aparecida Soares, L;Mota de Oliveira, F;Aparecida Oliveira Leopoldino, A;Netto Parentoni, A;Amaral Mendonça, V;Cristina Rodrigues Lacerda, A; The strong inverse association between plasma concentrations of soluble tumor necrosis factor receptors type 1 with adiponectin/leptin ratio in older women Cytokine 2024-01-27 [PMID: 38281360] (Human)		Human
Wu, WC;Shiu, C;Tong, TK;Leung, SO;Hui, CW; Suppression of NK Cell Activation by JAK3 Inhibition: Implication in the Treatment of Autoimmune Diseases Journal of immunology research 2023-12-08 [PMID: 38106519] (Human)		Human
Nikiforov, NG;Kirichenko, TV;Kubekina, MV;Chegodaev, YS;Zhuravlev, AD;Ilchuk, LA;Nikolaeva, MA;Arefieva, AS;Popov, MA;Verkhova, SS;Bagheri Ekta, M;Orekhov, AN; Macrophages derived from LPS-stimulated monocytes from individuals with subclinical atherosclerosis were characterized by increased pro-inflammatory activity Cytokine 2023-12-01 [PMID: 37918051] (Human)		Human
da Costa Teixeira, LA;Avelar, NCP;Peixoto, MFD;Parentoni, AN;Santos, JMD;Pereira, FSM;Danielewicz, AL;Leopoldino, AAO;Costa, SP;Arrieiro, AN;Soares, LA;da Silva Lage, VK;Prates, ACN;Taiar, R;de Carvalho Bastone, A;Oliveira, VC;Oliveira, MX;Costa, HS;Nobre, JNP;Brant, FP;Duarte, TC;Figueiredo, PHS;Mendonça, VA;Lacerda, ACR; Inflammatory biomarkers at different stages of Sarcopenia in older women Scientific reports 2023-06-26 [PMID: 37365209] (Human)		Human
LAC Teixeira, JM Dos Santos, AN Parentoni, LP Lima, TC Duarte, FP Brant, CDC Neves, FSM Pereira, NCP Avelar, AL Danielewic, AAO Leopoldino, SP Costa, AN Arrieiro, LA Soares, ACN Prates, JNP Nobre, A de Carvalh, VC de Oliveir, MX Oliveira, PH Scheidt Fi, HS Costa, V Amaral Men, R Taiar, AC Rodrigues Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study Journal of Clinical Medicine, 2022-12-02;11(23):. 2022-12-02 [PMID: 36498747] (Human)		Human
KEC Blokland, M Nizamoglu, H Habibie, T Borghuis, M Schuliga, BN Melgert, DA Knight, CA Brandsma, SD Pouwels, JK Burgess Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts Frontiers in Pharmacology, 2022-11-03;13(0):989169. 2022-11-03 [PMID: 36408252] (Human)		Human
J Feldt, AJ Donaubauer, J Welss, U Schneider, US Gaipl, F Paulsen Anti-inflammatory effects of an autologous gold-based serum therapy in osteoarthritis patients Scientific Reports, 2022-03-03;12(1):3560. 2022-03-03 [PMID: 35241691] (Human)		Human
SL Mathiasen, L Gall-Mas, IS Pateras, SDP Theodorou, MRJ Namini, MB Hansen, OCB Martin, CK Vadivel, K Ntostoglou, D Butter, M Givskov, C Geisler, AN Akbar, VG Gorgoulis, T Frisan, N Ødum, T Krejsgaard Bacterial genotoxins induce T�cell senescence Cell Reports, 2021-06-08;35(10):109220. 2021-06-08 [PMID: 34107253] (Human)		Human
M Ueno, I Miyagawa, K Nakano, S Iwata, K Hanami, S Fukuyo, S Kubo, Y Miyazaki, A Kawabe, H Yoshinari, S Nakayamada, Y Tanaka Effectiveness and safety of mepolizumab in combination with corticosteroids in patients with eosinophilic granulomatosis with polyangiitis Arthritis Research & Therapy, 2021-03-16;23(1):86. 2021-03-16 [PMID: 33726827] (Human)		Human
RP Madeira, LM Dal'Mas Ro, P de Cássia, C Mady, BM Ianni, AC Torrecilha New Biomarker in Chagas Disease: Extracellular Vesicles Isolated from Peripheral Blood in Chronic Chagas Disease Patients Modulate the Human Immune Response Journal of Immunology Research, 2021-01-11;2021(0):6650670. 2021-01-11 [PMID: 33506056] (Human)		Human
GR Kathamuthu, K Moideen, R Sridhar, D Baskaran, S Babu Altered plasma levels of &betaC and &gammaC chain cytokines and post-treatment modulation in tuberculous lymphadenitis Cytokine, 2020-12-17;138(0):155405. 2020-12-17 [PMID: 33341600] (Human)		Human
I Patlan, MP Jeffrey, D Lewis, J Green-John, S Dogra Salivary IL-8 and IL-1RA changes induced by exercise in cold-dry and normal conditions Cytokine, 2020-10-28;137(0):155347. 2020-10-28 [PMID: 33128925] (Human)		Human
C Malmhäll, K Johansson, C Winkler, S Alawieh, L Ekerljung, M Rådinger Altered miR-155 expression in Allergic Asthmatic airways Scand. J. Immunol, 2017-04-01;0(0):. 2017-04-01 [PMID: 28199728] (Human)		Human
Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency Proc. Natl. Acad. Sci. U.S.A, 2016-12-07;0(0):. 2016-12-07 [PMID: 27930337] (Human)		Human
Liukko A, Kinnunen T, Rytkonen-Nissinen M, Kailaanmaki A, Randell J, Maillere B, Virtanen T Human CD4+ T cell responses to the dog major allergen Can f 1 and its human homologue tear lipocalin resemble each other. PLoS ONE, 2014-05-29;9(5):e98461. 2014-05-29 [PMID: 24875388] (Human)		Human
Arndts , Kathrin, Specht , Sabine, Debrah , Alexande, Tamarozzi , Francesc, Klarmann Schulz , Ute, Mand , Sabine, Batsa , Linda, Kwarteng , Alexande, Taylor , Mark, Adjei , Ohene, Martin , Coralie, Layland , Laura E, Hoerauf , Achim Immunoepidemiological profiling of onchocerciasis patients reveals associations with microfilaria loads and ivermectin intake on both individual and community levels. PLoS Negl Trop Dis, 2014-02-20;8(2):e2679. 2014-02-20 [PMID: 24587458] (Human)		Human
Prigent L, Robineau M, Jouneau S, Morzadec C, Louarn L, Vernhet L, Fardel O, Sparfel L The aryl hydrocarbon receptor is functionally upregulated early in the course ofvhuman T-cell activation. Eur J Immunol, 2014-02-18;44(5):1330-40. 2014-02-18 [PMID: 24549985] (Human)		Human
Boisson B, Wang C, Pedergnana V, Wu L, Cypowyj S, Rybojad M, Belkadi A, Picard C, Abel L, Fieschi C, Puel A, Li X, Casanova J An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis. Immunity, 2013-10-10;39(4):676-86. 2013-10-10 [PMID: 24120361] (Human)		Human
Arndts K, Deininger S, Specht S, Klarmann U, Mand S, Adjobimey T, Debrah AY, Batsa L, Kwarteng A, Epp C, Taylor M, Adjei O, Layland LE, Hoerauf A Elevated adaptive immune responses are associated with latent infections of Wuchereria bancrofti. PLoS Negl Trop Dis, 2012-04-03;6(4):e1611. 2012-04-03 [PMID: 22509424] (Human)		Human
Ramana Rao PV, Rajasekaran S, Raja A Natural killer cell-mediated cytokine response among HIV-positive south Indians with pulmonary tuberculosis. J. Interferon Cytokine Res., 2010-01-01;30(1):33-42. 2010-01-01 [PMID: 20028198] (Human)		Human
Lamhamedi-Cherradi SE, Martin RE, Ito T, Kheradmand F, Corry DB, Liu YJ, Moyle M Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12. J. Immunol., 2008-05-01;180(9):6000-9. 2008-05-01 [PMID: 18424720] (Human)		Human
Nassenstein C, Kammertoens T, Veres TZ, Uckert W, Spies E, Fuchs B, Krug N, Braun A Neuroimmune crosstalk in asthma: dual role of the neurotrophin receptor p75NTR. J. Allergy Clin. Immunol., 2007-08-22;120(5):1089-96. 2007-08-22 [PMID: 17716721] (Mouse)		Mouse
Cox AL, Coles AJ, Nortje J, Bradley PG, Chatfield DA, Thompson SJ, Menon DK An investigation of auto-reactivity after head injury. J. Neuroimmunol., 2006-03-06;174(1):180-6. 2006-03-06 [PMID: 16519951] (Human)		Human
Freyne EJ, Lacrampe JF, Deroose F, Boeckx GM, Willems M, Embrechts W, Coesemans E, Willems JJ, Fortin JM, Ligney Y, Dillen LL, Cools WF, Goossens J, Corens D, De Groot A, Van Wauwe JP Synthesis and biological evaluation of 1,2,4-triazinylphenylalkylthiazolecarboxylic acid esters as cytokine-inhibiting antedrugs with strong bronchodilating effects in an animal model of asthma. J. Med. Chem., 2005-03-24;48(6):2167-75. 2005-03-24 [PMID: 15771459] (Human)		Human
Show All 26 Publications. Collapse Publications.

Array DY205

• IL-5 Antibodies
• IL-5 Antibody Pair
• IL-5 ELISA Kits
• IL-5 Proteins
• IL-5 Proteins and Enzymes
• IL-5 ELISAs