Human IL-1 alpha/IL-1F1 DuoSet ELISA, 15 Plate

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IL-1 alpha (Interleukin-1 alpha) is a cytokine that is induced during microbial exposure and promotes the release of multiple inflammatory mediators and acute phase proteins. It also supports hematopoietic stem cell expansion, promotes neutrophil mobilization from the bone marrow, and promotes osteoclast formation. IL-1 alpha signals through a receptor complex composed of IL-1 RI and IL-1 RAcP. It also binds the decoy receptor IL-1 RII which associates with IL-1 RAcP but does not transduce signaling.

We have publications tested in 2 confirmed species: Human, Mouse.

Showing Publications 1 - 10 of 37. Show All 37 Publications. Collapse Publications.

Publications using DY200	Applications	Species
Klein, R;Onyuru, J;Viera, EM;Putnam, CD;Hoffman, HM;Hastings, ML; Modulating NLRP3 splicing with antisense oligonucleotides to control pathological inflammation bioRxiv : the preprint server for biology 2024-09-06 [PMID: 39282364] (Human)		Human
Nasr, MA;Aldous, A;Daniels, J;Joy, C;Capozzi, E;Yang, M;Moriarty, P;Emmanuel-Baker, V;Malcolm, S;Green, SJ;Gomez-Lobo, V;Ghosh, M; Effect of progestin-based contraceptives on HIV-associated vaginal immune biomarkers and microbiome in adolescent girls PloS one 2024-07-15 [PMID: 39008499] (Human)		Human
Atasoy-Zeybek, A;Hawse, GP;Nagelli, CV;De Padilla, CL;Abdel, MP;Evans, CH; Transcriptomic changes during the replicative senescence of human articular chondrocytes bioRxiv : the preprint server for biology 2023-11-07 [PMID: 37986862] (Human)		Human
Zobel, CM;Wenzel, W;Krüger, JP;Baumgarten, U;Wagelöhner, T;Neumann, N;Foroutan, B;Müller, R;Müller, A;Rauschning, D;Schü beta ler, M;Scheit, L;Weinreich, F;Oltmanns, K;Keidel, F;Koch, M;Spethmann, S;Schreiner, M; Serum interleukin-6, procalcitonin, and C-reactive protein at hospital admission can identify patients at low risk for severe COVID-19 progression Frontiers in microbiology 2023-10-23 [PMID: 37937220] (Human)		Human
Gysan, MR;Milacek, C;Bal, C;Zech, A;Brugger, J;Milos, RI;Antoniewicz, L;Idzko, M;Gompelmann, D; Ventilatory support and inflammatory peptides in hospitalised patients with COVID-19: A prospective cohort trial PloS one 2023-11-02 [PMID: 37917760] (Human)		Human
Membrane-bound Interleukin-1 alpha mediates leukocyte adhesion during atherogenesis [PMID: 37701434] (Human)		Human
YY Chao, A Puhach, D Frieser, M Arunkumar, L Lehner, T Seeholzer, A Garcia-Lop, M van der Wa, S Fibi-Smeta, A Dietschman, T Sommermann, T ?ikovi?, L Taher, MS Gresnigt, SJ Vastert, F van Wijk, G Panagiotou, D Krappmann, O Gro beta , CE Zielinski Human TH17 cells engage gasdermin E pores to release IL-1alpha on NLRP3 inflammasome activation Nature Immunology, 2023-01-05;0(0):. 2023-01-05 [PMID: 36604548] (Human)		Human
H Chen, ME Diolaiti, PC O'Leary, A Rojc, NJ Krogan, M Kim, A Ashworth A whole genome CRISPR screen identifies AHR loss as a mechanism of PARP7 inhibitor resistance Molecular Cancer Therapeutics, 2022-07-05;0(0):. 2022-07-05 [PMID: 35439318] (Human)		Human
SC Lean, RL Jones, SA Roberts, AEP Heazell A prospective cohort study providing insights for markers of adverse pregnancy outcome in older mothers BMC pregnancy and childbirth, 2021-10-20;21(1):706. 2021-10-20 [PMID: 34670515] (Human)		Human
SH Kim, SH Hong, JH Lee, DH Lee, K Jung, JY Yang, HS Shin, J Lee, J Jeong, JH Oh Skin Sensitization Evaluation of Carbon-Based Graphene Nanoplatelets Toxics, 2021-03-17;9(3):. 2021-03-17 [PMID: 33803047] (Human)		Human
K Bernau, JP Leet, H Floerke, EM Bruhn, AL Noll, IS McDermott, S Esnault, NN Jarjour, N Sandbo Interleukin-1&alpha Is a Critical Mediator of the Response of Human Bronchial Fibroblasts to Eosinophilic Inflammation Cells, 2021-03-02;10(3):. 2021-03-02 [PMID: 33801398] (Human)		Human
SH Jun, H Kim, H Lee, JE Song, SG Park, NG Kang Synthesis of Retinol-Loaded Lipid Nanocarrier via Vacuum Emulsification to Improve Topical Skin Delivery Polymers, 2021-03-08;13(5):. 2021-03-08 [PMID: 33800335] (Human)		Human
T Takemoto, R Kaetsu, M Hanayama, Y Ishiyama, M Sadamura, K Nishio, M Tsunoda, M Asano, M Motoyoshi Acid-electrolyzed functional water-induces Interleukin-1&alpha release from Intracellular Storage Sites in Oral Squamous Cell Carcinoma International Journal of Medical Sciences, 2021-02-18;18(8):1746-1752. 2021-02-18 [PMID: 33746591] (Human)		Human
S Niklander, D Bandaru, DW Lambert, KD Hunter ROCK inhibition modulates the senescence-associated secretory phenotype (SASP) in oral keratinocytes FEBS Open Bio, 2020-11-06;0(0):. 2020-11-06 [PMID: 33095981] (Human)		Human
S Tumpara, B Martinez-D, G Gomez-Mari, B Liu, DS DeLuca, E Korenbaum, D Jonigk, F Jugert, FM Wurm, MJ Wurm, T Welte, S Janciauski The Delivery of &alpha1-Antitrypsin Therapy Through Transepidermal Route: Worthwhile to Explore Front Pharmacol, 2020-07-03;11(0):983. 2020-07-03 [PMID: 32719598] (Human)		Human
A Aimond, K Calabro, C Audoin, E Olivier, M Dutot, P Buron, P Rat, O Laprévote, S Prado, E Roulland, OP Thomas, G Genta-Jouv Cytotoxic and Anti-Inflammatory Effects of Ent-Kaurane Derivatives Isolated from the Alpine Plant Sideritis hyssopifolia Molecules, 2020-01-29;25(3):. 2020-01-29 [PMID: 32013210] (Human)		Human
S Saito, M Ohtsu, M Asano, T Ishigami Ouabain signaling in oral squamous cell carcinoma cells J Oral Sci, 2019-09-20;0(0):. 2019-09-20 [PMID: 31548455] (Human)		Human
X Jiang, F Wang, Y Wang, A Gisterå, J Roy, G Paulsson-B, U Hedin, A Lerman, GK Hansson, J Herrmann, ZQ Yan Inflammasome-Driven Interleukin-1α and�Interleukin-1? Production in Atherosclerotic Plaques Relates to Hyperlipidemia and Plaque Complexity JACC Basic Transl Sci, 2019-06-24;4(3):304-317. 2019-06-24 [PMID: 31312755] (Human)		Human
M Ma, CM Percopo, DE Sturdevant, AC Sek, HD Komarow, HF Rosenberg Cytokine Diversity in Human Peripheral Blood Eosinophils: Profound Variability of IL-16 J. Immunol., 2019-06-10;0(0):. 2019-06-10 [PMID: 31182481] (Human)		Human
S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist Stem Cells, 2019-05-13;0(0):. 2019-05-13 [PMID: 31002437] (Human)		Human
R Saga, K Hasegawa, K Murata, M Chiba, T Nakamura, K Okumura, E Tsuruga, Y Hosokawa Regulation of radiosensitivity by 4-methylumbelliferone via the suppression of interleukin-1 in fibrosarcoma cells Oncol Lett, 2019-01-29;17(3):3555-3561. 2019-01-29 [PMID: 30867797] (Human)		Human
M Mastri, A Tracz, CR Lee, M Dolan, K Attwood, JG Christense, S Liu, JML Ebos A Transient Pseudosenescent Secretome Promotes Tumor Growth after Antiangiogenic Therapy Withdrawal Cell Rep, 2018-12-26;25(13):3706-3720.e8. 2018-12-26 [PMID: 30590043] (Human)		Human
CC Sheth, RM López-Pedr, MDM Jovani-San, R González-M, V Veses Modulation of salivary cytokines in response to alcohol, tobacco and caffeine consumption: a pilot study Sci Rep, 2018-11-12;8(1):16687. 2018-11-12 [PMID: 30420770] (Human)		Human
M Kusunoki, E Sata, K Nishio, T Tanaka, T Nishida, N Sugano, S Sato, M Asano Acid-electrolyzed functional water induces extracellular matrix metalloproteinase inducer, a possible novel alarmin, secretion from oral squamous cell carcinoma cell lines Int J Med Sci, 2018-09-07;15(12):1365-1372. 2018-09-07 [PMID: 30275765] (Human)		Human
RF Hamilton, Z Wu, S Mitra, A Holian The Effects of Varying Degree of MWCNT Carboxylation on Bioactivity in Various In Vivo and In Vitro Exposure Models Int J Mol Sci, 2018-01-25;19(2):. 2018-01-25 [PMID: 29370073] (Human)		Human
B Lagrange, S Benaoudia, P Wallet, F Magnotti, A Provost, F Michal, A Martin, F Di Lorenzo, BF Py, A Molinaro, T Henry Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11 Nat Commun, 2018-01-16;9(1):242. 2018-01-16 [PMID: 29339744] (Human)		Human
E Briend, GJ Ferguson, M Mori, G Damera, K Stephenson, NA Karp, S Sethi, CK Ward, MA Sleeman, JS Erjefält, DK Finch IL-18 associated with lung lymphoid aggregates drives IFN? production in severe COPD Respir. Res., 2017-08-22;18(1):159. 2017-08-22 [PMID: 28830544] (Human)		Human
LM Scott, AH Bryant, A Rees, B Down, RH Jones, CA Thornton Production and regulation of interleukin-1 family cytokines at the materno-fetal interface Cytokine, 2017-07-13;0(0):. 2017-07-13 [PMID: 28712670] (Human)		Human
GR Kathamuthu, K Moideen, D Baskaran, VV Banurekha, D Nair, G Sekar, R Sridhar, B Vidyajayan, G Gajendrara, DK Parandhama, A Srinivasan, S Babu TB lymphadenitis is associated with enhanced baseline and antigen - specific induction of Type 1 and Type 17 cytokines and reduced IL-1? and IL-18 at the site of infection Clin. Vaccine Immunol, 2017-05-05;0(0):. 2017-05-05 [PMID: 28249842] (Human)		Human
Bortezomib treatment sensitizes oncolytic HSV-1 treated tumors to NK cell immunotherapy Clin Cancer Res, 2016-07-07;0(0):. 2016-07-07 [PMID: 27390350] (Mouse)		Mouse
Simanski M, Rademacher F, Schroder L, Glaser R, Harder J The Inflammasome and the Epidermal Growth Factor Receptor (EGFR) Are Involved in the Staphylococcus aureus-Mediated Induction of IL-1alpha and IL-1beta in Human Keratinocytes. PLoS ONE, 2016-01-25;11(1):e0147118. 2016-01-25 [PMID: 26808616] (Human)		Human
Haddad L, Sirois M Angiopoietin-1 upregulates de novo expression of IL-1beta and Il1-Ra, and the exclusive release of Il1-Ra from human neutrophils. PLoS ONE, 2014-02-12;9(2):e88980. 2014-02-12 [PMID: 24563688] (Human)		Human
Polyak M, Vivithanaporn P, Maingat F, Walsh J, Branton W, Cohen E, Meeker R, Power C Differential type 1 interferon-regulated gene expression in the brain during AIDS: interactions with viral diversity and neurovirulence. FASEB J, 2013-04-22;27(7):2829-44. 2013-04-22 [PMID: 23608145] (Human)		Human
Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33. J. Exp. Med., 2012-07-16;209(8):1505-17. 2012-07-16 [PMID: 22802353] (Human)		Human
Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling. J. Clin. Invest., 2007-12-01;117(12):3664-3672. 2007-12-01 [PMID: 17992260] (Human)		Human
Palmer G, Trolliet S, Talabot-Ayer D, Mezin F, Magne D, Gabay C Pre-interleukin-1alpha expression reduces cell growth and increases interleukin-6 production in SaOS-2 osteosarcoma cells: Differential inhibitory effect of interleukin-1 receptor antagonist (icIL-1Ra1). Cytokine, 2005-07-21;31(2):153-60. 2005-07-21 [PMID: 15923123] (Human)		Human
Schaub FJ, Liles WC, Ferri N, Sayson K, Seifert RA, Bowen-Pope DF Fas and Fas-associated death domain protein regulate monocyte chemoattractant protein-1 expression by human smooth muscle cells through caspase- and calpain-dependent release of interleukin-1alpha. Circ. Res., 2003-08-28;93(6):515-22. 2003-08-28 [PMID: 12946945] (Human)		Human
Show All 37 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Patricia Carulla Martí			06/22/2023	View Summary Sample Tested Cultured Human Keratinocytes,Supernatant Human Epidermal keratinocytes (HEKa) in presence or absence of Poly(I:C) Lot P309019

Array DY200

• IL-1 alpha/IL-1F1 Antibodies
• IL-1 alpha/IL-1F1 Antibody Pair
• IL-1 alpha/IL-1F1 ELISA Kits
• IL-1 alpha/IL-1F1 Proteins
• IL-1 alpha/IL-1F1 ELISAs
• IL-1 alpha/IL-1F1 Proteins and Enzymes