Human IFN-gamma Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Interferon-gamma (IFN-gamma ) is an important immunomodulatory cytokine, affecting both the innate and adaptive immune systems. It was discovered in 1965 as a soluble anti-viral factor and has since been shown to promote host defense against a wide variety of pathogens (1, 2). Additionally, it has been shown to promote autophagy and apoptosis, and to have anti-proliferative, anti-angiogenic, and anti-tumorigenic properties (1, 3, 4). IFN-gamma is primarily secreted by natural killer (NK) cells (5-7), activated CD8+ T cells (8), Th1 CD4+ T cells (9), NKT cells (10, 11), and macrophages (12-16), but it has also been shown to be produced by a number of other cell types including dendritic cells (17), gamma δ T cells (18), group 1 ILCs (19), keratinocytes (20), neutrophils (21), mast cells (22), and neurons (23).

The biologically active form of IFN-gamma is a non-covalently linked homodimer (24), which binds with high affinity to IFN-gamma R1/CD119 and subsequently recruits IFN-gamma R2 to form the functional heterotetrameric receptor complex. Formation of this complex leads to phosphorylation and activation of the Janus kinases, Jak1 and Jak2, which in turn phosphorylate and activate STAT1. STAT1 homodimerizes and translocates to the nucleus where it binds to IFN-gamma -activated sequence (GAS) elements in the promoters of target genes to regulate their transcription. Many of the IFN-gamma /STAT1 target genes are transcription factors that then drive the expression of secondary response genes. Additionally, IFN-gamma signaling has been shown to activate MAPK, PI 3-K/Akt, and the NF-kappa B signaling pathways, leading to the expression of multiple other genes. IFN-gamma signaling plays a key role in host defense by promoting macrophage activation, upregulating the expression of antigen processing and presentation molecules, driving the development and activation of Th1 cells, enhancing natural killer cell activity, regulating B cell functions, and inducing the production of chemokines that promote effector cell trafficking to sites of inflammation. 

Due to its immunoregulatory activities, IFN-gamma has been used as a therapeutic agent for treating a range of bacterial, fungal, helminth, protozoan, and viral infections, immunodeficiency syndromes, multi-drug resistant tuberculosis (MDR-TB), and sepsis (1, 25-34). Additionally, it has been used as an anti-tumor agent to improve patient survival in a number of different types of cancer due to its pro-apoptotic and anti-angiogenic effects (3, 35). In contrast, IFN-gamma has been suggested to be involved in the progression of cardiac diseases as elevated levels of this cytokine have been detected in the serum of patients with chronic heart failure, as well as in atherosclerotic lesions and in myocardial tissues of patients with Chagas' cardiomyopathy (1, 36, 37). Similarly, high levels of IFN-gamma have been found in the serum and/or cerebrospinal fluid of patients with neurodegenerative diseases such as Amyotrophic lateral sclerosis and Parkinson's disease (38, 39), suggesting that IFN-gamma may also be involved in neurodegenerative disease progression and serve as a clinical biomarker. Additionally, there is recent evidence suggesting that IFN-gamma may also have context-dependent proliferative and pro-tumorigenic effects (3).

We have publications tested in 6 confirmed species: Human, Mouse, Bovine, Cynomolgus Monkey, Primate, Primate - Macaca mulatta (Rhesus Macaque).

We have publications tested in 2 applications: Cell Culture, ELISA Capture.

Showing Publications 1 - 10 of 219. Show All 219 Publications. Collapse Publications.

Publications using DIF50C	Applications	Species
Yang, W-S;Kim, D;Kang, S;Lai, C-J;Cha, I;Chang, P-C;Jung, JU; Development of KSHV vaccine platforms and chimeric MHV68-K-K8.1 glycoprotein for evaluating the in vivo immunogenicity and efficacy of KSHV vaccine candidates mBio 2024-10-30 [PMID: 39475238] (Mouse)		Mouse
Yang, T;Dong, Y;Wang, G;Guan, X; SOX13-mediated transcription of LRP11 enhances malignant properties of tumor cells and CD8+ T cell inactivation in breast cancer through the ?-catenin/PD-L1 axis Cellular signalling 2024-09-05 [PMID: 39243917] (Mouse)		Mouse
Fourie, AM;Cheng, X;Chang, L;Greving, C;Li, X;Knight, B;Polidori, D;Patrick, A;Bains, T;Steele, R;Allen, SJ;Patch, RJ;Sun, C;Somani, S;Bhandari, A;Liu, D;Huie, K;Li, S;Rodriguez, MA;Xue, X;Kannan, A;Kosoglou, T;Sherlock, JP;Towne, J;Holland, MC;Modi, NB; JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans Scientific reports 2024-07-30 [PMID: 39080319] (Human)		Human
Peng, H;Endo, Y;Wu, WJ; Define Critical Parameters of Trastuzumab-Mediated ADCC Assays via Assay Optimization Processes, Focusing on the Impact of Cryopreserved Effector Cells on Assay Performance Cancers 2024-06-27 [PMID: 39001429] (Human)		Human
Chen, Y;Wang, L;Chen, N;Tang, G; Metformin induces tumor immunogenic cell death in ovarian cancer by activating AMPK pathway Translational oncology 2024-07-08 [PMID: 38981246] (Human)		Human
Karwaciak, I;Pastwi?ska, J;Sa?kowska, A;Bachorz, RA;Ratajewski, M; Evaluation of the Activity of Cardiac Glycosides on ROR? and ROR?T Nuclear Receptors Archives of biochemistry and biophysics 2024-07-04 [PMID: 38971421] (Human)		Human
Ao, L;Shi, J;Gan, J;Yu, W;Du, H; Effects of dexmedetomidine and ketorolac applied for patient?controlled analgesia on the balance of Th1/Th2 and level of VEGF in patients undergoing laparoscopic surgery for cervical cancer: A randomized controlled trial Oncology letters 2024-08-01 [PMID: 38939623] (Human)		Human
Shaw, TI;Wagner, J;Tian, L;Wickman, E;Poudel, S;Wang, J;Paul, R;Koo, SC;Lu, M;Sheppard, H;Fan, Y;O'Neill, FH;Lau, CC;Zhou, X;Zhang, J;Gottschalk, S; Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression. Nature communications 2024-05-03 [PMID: 38702309] (Human)		Human
Scovino, AM;Dahab, EC;Diniz-Lima, I;de Senna Silveira, E;Barroso, SPC;Cardoso, KM;Nico, D;Makhoul, GJ;da Silva-Junior, EB;Freire-de-Lima, CG;Freire-de-Lima, L;Fonseca, LMD;Valente, N;Nacife, V;Machado, A;Araújo, M;Vieira, GF;Pauvolid-Corrêa, A;Siqueira, M;Morrot, A; A Comparative Analysis of Innate Immune Responses and the Structural Characterization of Spike from SARS-CoV-2 Gamma Variants and Subvariants Microorganisms 2024-04-02 [PMID: 38674664] (Human)		Human
Chakraborty, A;Onda, M;O'Shea, T;Wei, J;Liu, X;Bera, TK;Pastan, I; A bispecific antibody that targets the membrane-proximal region of mesothelin and retains high anticancer activity in the presence of shed mesothelin Molecular cancer therapeutics 2024-04-22 [PMID: 38647528] (Human)		Human
Golubovskaya, V;Sienkiewicz, J;Sun, J;Zhang, S;Huang, Y;Zhou, H;Harto, H;Xu, S;Berahovich, R;Wu, L; CAR-NK Cells Generated with mRNA-LNPs Kill Tumor Target Cells In Vitro and In Vivo International journal of molecular sciences 2023-08-29 [PMID: 37686170] (Human)		Human
Wright, KM;DiNapoli, SR;Miller, MS;Aitana Azurmendi, P;Zhao, X;Yu, Z;Chakrabarti, M;Shi, W;Douglass, J;Hwang, MS;Hsiue, EH;Mog, BJ;Pearlman, AH;Paul, S;Konig, MF;Pardoll, DM;Bettegowda, C;Papadopoulos, N;Kinzler, KW;Vogelstein, B;Zhou, S;Gabelli, SB; Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen Nature communications 2023-08-21 [PMID: 37604828] (Human)		Human
Golubovskaya, V;Sienkiewicz, J;Sun, J;Huang, Y;Hu, L;Zhou, H;Harto, H;Xu, S;Berahovich, R;Bodmer, W;Wu, L; mRNA-Lipid Nanoparticle (LNP) Delivery of Humanized EpCAM-CD3 Bispecific Antibody Significantly Blocks Colorectal Cancer Tumor Growth Cancers 2023-05-22 [PMID: 37345198] (Human)		Human
Abramiuk, M;Frankowska, K;Ku?ak, K;Tarkowski, R;Mertowska, P;Mertowski, S;Grywalska, E; Possible Correlation between Urocortin 1 (Ucn1) and Immune Parameters in Patients with Endometriosis International journal of molecular sciences 2023-04-24 [PMID: 37175494] (Human)		Human
SR Boreddy, R Nair, PK Pandey, A Kuriakose, SB Marigowda, C Dey, A Banerjee, H Kulkarni, M Sagar, SR Krishn, S Rao, M A R, V Tiwari, B Alke, PK Mv, M Shri, C Dhamne, S Patel, P Sharma, S Periyasamy, J Bhatnagar, MA Kuriakose, RB Reddy, A Suresh, S Sreenivas, N Govindappa, PR Moole, U Bughani, SL Tan, P Nair BCA101 is a Tumor-Targeted Bifunctional Fusion Antibody that Simultaneously Inhibits EGFR and TGF-beta Signalling to Durably Suppress Tumor Growth Cancer Research, 2023-06-02;0(0):. 2023-06-02 [PMID: 37074042] (Human)		Human
G Silva, AF Rodrigues, S Ferreira, C Matos, RP Eleutério, G Marques, K Kucheryava, AR Lemos, PMF Sousa, R Castro, A Barbas, D Simão, PM Alves Novel scFv against Notch Ligand JAG1 Suitable for Development of Cell Therapies toward JAG1-Positive Tumors Biomolecules, 2023-03-02;13(3):. 2023-03-02 [PMID: 36979394] (Human)		Human
AG Saleh, AY Shehab, R Abdul-Ghan, AF Allam, MM Osman, HS Ibrahim, HA El-Taweel, EA Moneer, NA Hagras, HF Farag Key cytokines and hematological parameters in patients with uncomplicated falciparum malaria in Hodeidah, Yemen Cytokine, 2023-02-27;164(0):156156. 2023-02-27 [PMID: 36857851] (Human)		Human
F Parween, SP Singh, HH Zhang, N Kathuria, FA Otaizo-Car, A Shamsaddin, PJ Gardina, S Ganesan, J Kabat, HA Lorenzi, TG Myers, JM Farber Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells bioRxiv : the preprint server for biology, 2023-02-13;0(0):. 2023-02-13 [PMID: 36789428] (Human)		Human
SY Cho, SM Jeong, YJ Jeon, SJ Yang, JE Hwang, BM Yoo, HS Kim WT1 Pulsed Human CD141+ Dendritic Cell Vaccine Has High Potential in Solid Tumor-Targeted Immunotherapy International Journal of Molecular Sciences, 2023-01-12;24(2):. 2023-01-12 [PMID: 36675017] (Human)		Human
MC Giménez, M Luxwolda, EG Van Stipri, PP Bollen, RL Hoekman, MA Koopmans, PR Arany, MR Krames, AC Berends, RA Hut, MCM Gordijn Effects of Near-Infrared Light on Well-Being and Health in Human Subjects with Mild Sleep-Related Complaints: A Double-Blind, Randomized, Placebo-Controlled Study Biology, 2022-12-29;12(1):. 2022-12-29 [PMID: 36671752] (Human)		Human
A Barilli, R Visigalli, F Ferrari, G Recchia Lu, M Soli, V Dall'Asta, BM Rotoli Growth Arrest of Alveolar Cells in Response to Cytokines from Spike S1-Activated Macrophages: Role of IFN-gamma Biomedicines, 2022-12-01;10(12):. 2022-12-01 [PMID: 36551841] (Human)		Human
P Yuti, Y Wutti-In, N Sawasdee, K Kongkhla, N Phanthapho, K Choomee, T Chieochans, A Panya, M Junking, PT Yenchitsom, J Sujjitjoon Anti-CD19 chimeric antigen receptor T cells secreting anti-PD-L1 single-chain variable fragment attenuate PD-L1 mediated T cell inhibition International immunopharmacology, 2022-11-23;113(0):109442. 2022-11-23 [PMID: 36435066] (Human)		Human
CV Gonçalves, IS Ribeiro, MPL Galantini, IPR Muniz, PHB Lima, GS Santos, RAA da Silva Inflammaging and body composition: New insights in diabetic and hypertensive elderly men Experimental gerontology, 2022-10-28;170(0):112005. 2022-10-28 [PMID: 36341786] (Human)		Human
J Milosevic, M Jurisevic, V Grbovic, I Jovanovic, N Gajovic, A Jurisic-Sk Potential Protective Role of Galectin-3 in Patients with Gonarthrosis and Diabetes Mellitus: A Cross-Sectional Study International Journal of Environmental Research and Public Health, 2022-09-13;19(18):. 2022-09-13 [PMID: 36141752] (Human)		Human
R Yoshida, M Saigi, T Tani, BF Springer, H Shibata, S Kitajima, NR Mahadevan, M Campisi, W Kim, Y Kobayashi, TC Thai, K Haratani, Y Yamamoto, SK Sundararam, EH Knelson, A Vajdi, I Canadas, R Uppaluri, CP Paweletz, JJ Miret, PH Lizotte, PC Gokhale, PA Janne, DA Barbie MET-induced CD73 restrains STING-mediated immunogenicity of EGFR-mutant lung cancer Cancer Research, 2022-11-02;0(0):. 2022-11-02 [PMID: 36066413] (Human)		Human
Y Bian, T Lin, T Jakos, X Xiao, J Zhu The Generation of Dual-Targeting Fusion Protein PD-L1/CD47 for the Inhibition of Triple-Negative Breast Cancer Biomedicines, 2022-07-30;10(8):. 2022-07-30 [PMID: 36009390] (Human)		Human
MPL Galantini, IS Ribeiro, CV Gonçalves, IPR Muniz, PHB Lima, GS Santos, RAA da Silva The sweet fuel of inflammation: New perspectives on the complex web that interconnects diabetes Experimental gerontology, 2022-07-30;167(0):111905. 2022-07-30 [PMID: 35918042] (Human)		Human
W Singhatana, S Kitpakorns, M Toso, P Pavasant IFNgamma-primed periodontal ligament cells regulate T-cell responses via IFNgamma-inducible mediators and ICAM-1-mediated direct cell contact Royal Society open science, 2022-07-27;9(7):220056. 2022-07-27 [PMID: 35911203] (Human)		Human
N Mohan, A Agrawal, Y Shen, KL Winarski, Y Endo, M Dokmanovic, D Schmiel, J Zheng, DS Rotstein, LC Pelosof, WJ Wu Comparative Characterization of Different Molecular Formats of Bispecific Antibodies Targeting EGFR and PD-L1 Oncogene, 2022-06-29;14(7):. 2022-06-29 [PMID: 35890277] (Human)		Human
J Saetang, N Roongsawan, S Sangkhatha, SP Voravuthik, N Sangkaew, N Prompat, T Srichana, V Tipmanee Surface cysteine to serine substitutions in IL-18 reduce aggregation and enhance activity PeerJ, 2022-07-05;10(0):e13626. 2022-07-05 [PMID: 35811828] (Human)		Human
TA Karginov, A Ménoret, AT Vella Optimal CD8+ T cell effector function requires costimulation-induced RNA-binding proteins that reprogram the transcript isoform landscape Nature Communications, 2022-06-20;13(1):3540. 2022-06-20 [PMID: 35725727] (Human)		Human
N Jirapongwa, S Thongchot, W Chiraphapp, T Chieochans, D Sa-Nguanra, M Warnnissor, P Thuwajit, PT Yenchitsom, C Thuwajit Mesothelin?specific T cell cytotoxicity against triple negative breast cancer is enhanced by 40s ribosomal protein subunit 3?treated self?differentiated dendritic cells Oncology reports, 2022-05-26;48(1):. 2022-05-26 [PMID: 35616135] (Human)		Human
S Luo, R Wu, Q Li, G Zhang Epigenetic Regulation of IFI44L Expression in Monocytes Affects the Functions of Monocyte-Derived Dendritic Cells in Systemic Lupus Erythematosus Journal of Immunology Research, 2022-05-10;2022(0):4053038. 2022-05-10 [PMID: 35592687] (Human)		Human
G Rodionov, M Rosenzwaig, MS Tzadok, M Kvint, E Gevir, E Zorde-Khva, A Peled, S Yarkoni, A Ofer Short treatment of peripheral blood cells product with Fas ligand using closed automated cell processing system significantly reduces immune cell reactivity of the graft in vitro and in vivo Bone marrow transplantation, 2022-05-10;0(0):. 2022-05-10 [PMID: 35538142] (Human)		Human
S Tomar, J Zhang, M Khanal, J Hong, A Venugopala, Q Jiang, M Sengupta, M Miettinen, N Li, I Pastan, M Ho, R Hassan Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors Molecular Cancer Therapeutics, 2022-07-05;21(7):1195-1206. 2022-07-05 [PMID: 35499461] (Mouse)		Mouse
C Zhong, B Tao, X Li, W Xiang, L Peng, T Peng, L Chen, X Xia, J You, X Yang HOXA-AS2 contributes to regulatory T cell proliferation and immune tolerance in glioma through the miR-302a/KDM2A/JAG1 axis Cell Death & Disease, 2022-02-18;13(2):160. 2022-02-18 [PMID: 35181676] (Human)		Human
C Udjus, I Sjaastad, U Hjørnholm, TK Tunestveit, P Hoffmann, A Hinojosa, EKS Espe, G Christense, OH Skjønsberg, KO Larsen, M Rostrup Extreme altitude induces divergent mass reduction of right and left ventricle in mountain climbers Physiological Reports, 2022-02-01;10(3):e15184. 2022-02-01 [PMID: 35146955] (Human)		Human
B Orts, A Gutierrez, L Madero, L Sempere, R Frances, P Zapater Clinical and Immunological Factors Associated with Recommended Trough Levels of Adalimumab and Infliximab in Patients with Crohn's Disease Frontiers in Pharmacology, 2022-01-03;12(0):795272. 2022-01-03 [PMID: 35046819] (Human)		Human
WS Khalaf, MRA Mahmoud, WF Elkhatib, HR Hashem, WE Soliman Phenotypic characterization of NKT-like cells and evaluation of specifically related cytokines for the prediction of unexplained recurrent miscarriage Heliyon, 2021-11-16;7(11):e08409. 2021-11-16 [PMID: 34849421] (Human)		Human
K Kurianowic, M Klatka, A Polak, A Hymos, D B?bnowska, M Podgajna, R Hrynkiewic, O Sierawska, P Nied?wiedz Impaired Innate Immunity in Pediatric Patients Type 1 Diabetes-Focus on Toll-like Receptors Expression International Journal of Molecular Sciences, 2021-11-09;22(22):. 2021-11-09 [PMID: 34830017] (Human)		Human
Y Chen, L Wang, M Zheng, C Zhu, G Wang, Y Xia, EJ Blumenthal, W Mao, Y Wan Engineered extracellular vesicles for concurrent Anti-PDL1 immunotherapy and chemotherapy Bioactive materials, 2021-07-21;9(0):251-265. 2021-07-21 [PMID: 34820569] (Human)		Human
VR Ribeiro, M Romao-Veig, PR Nunes, ML Matias, JC Peracoli, MTS Peracoli Vitamin D modulates the transcription factors of T cell subsets to anti-inflammatory and regulatory profiles in preeclampsia International immunopharmacology, 2021-11-20;0(0):108366. 2021-11-20 [PMID: 34810124] (Human)		Human
MT Guagnano, C D'Angelo, D Caniglia, P Di Giovann, E Celletti, E Sabatini, L Speranza, M Bucci, F Cipollone, R Paganelli Improvement of Inflammation and Pain after Three Months' Exclusion Diet in Rheumatoid Arthritis Patients Nutrients, 2021-10-09;13(10):. 2021-10-09 [PMID: 34684536] (Human)		Human
IS Ribeiro, ÍS Pereira, MPL Galantini, DP Santos, MF Teles, IPR Muniz, GS Santos, RAA Silva Regular physical activity reduces the effects of inflammaging in diabetic and hypertensive men Experimental gerontology, 2021-09-20;155(0):111558. 2021-09-20 [PMID: 34547405] (Human)		Human
KS Lee, WY Chung, JE Park, YJ Jung, JH Park, SS Sheen, KJ Park Interferon-gamma-Inducible Chemokines as Prognostic Markers for Lung Cancer International Journal of Environmental Research and Public Health, 2021-09-04;18(17):. 2021-09-04 [PMID: 34501934] (Human)		Human
MS Hwang, MS Miller, P Thirawatan, J Douglass, KM Wright, EH Hsiue, BJ Mog, TY Aytenfisu, MB Murphy, P Aitana Azu, AD Skora, AH Pearlman, S Paul, SR DiNapoli, MF Konig, C Bettegowda, DM Pardoll, N Papadopoul, KW Kinzler, B Vogelstein, S Zhou, SB Gabelli Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens Nature Communications, 2021-09-06;12(1):5271. 2021-09-06 [PMID: 34489470] (Human)		Human
J Petersson, S Askman, Å Pettersson, S Wichert, T Hellmark, ÅCM Johansson, M Hansson Bone Marrow Neutrophils of Multiple Myeloma Patients Exhibit Myeloid-Derived Suppressor Cell Activity Journal of Immunology Research, 2021-08-06;2021(0):6344344. 2021-08-06 [PMID: 34414242] (Human)		Human
S Nakajima, K Mimura, T Matsumoto, AK Thar Min, M Ito, H Nakano, P Neupane, Y Kanke, H Okayama, M Saito, T Momma, Y Watanabe, H Hanayama, S Hayase, Z Saze, K Kono The effects of T-DXd on the expression of HLA class I and chemokines CXCL9/10/11 in HER2-overexpressing gastric cancer cells Scientific Reports, 2021-08-19;11(1):16891. 2021-08-19 [PMID: 34413454] (Human)		Human
RL Relf, BJ Lee, G Eichhorn, MS Flint, L Beale, N Maxwell Thermoregulation is not impaired in breast cancer survivors during moderate-intensity exercise performed in warm and hot environments Physiological Reports, 2021-07-01;9(14):e14968. 2021-07-01 [PMID: 34291605] (Human)		Human
C Geuijen, P Tacken, LC Wang, R Klooster, PF van Loo, J Zhou, A Mondal, YB Liu, A Kramer, T Condamine, A Volgina, LJA Hendriks, H van der Ma, E Rovers, S Engels, F Fransen, R den Blanke, V Zondag-van, A Basmeleh, W Bartelink, A Kulkarni, W Marissen, CY Huang, L Hall, S Harvey, S Kim, M Martinez, S O'Brien, E Moon, S Albelda, C Kanellopou, S Stewart, H Nastri, ABH Bakker, P Scherle, T Logtenberg, G Hollis, J de Kruif, R Huber, PA Mayes, M Throsby A human CD137�PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade Nature Communications, 2021-07-21;12(1):4445. 2021-07-21 [PMID: 34290245] (Cynomolgus Monkey, Human)		Cynomolgus Monkey, Human
CF Huang, SM Hsieh, SC Pan, YS Huang, SC Chang Dose-Related Aberrant Inhibition of Intracellular Perforin Expression by S1 Subunit of Spike Glycoprotein That Contains Receptor-Binding Domain from SARS-CoV-2 Microorganisms, 2021-06-15;9(6):. 2021-06-15 [PMID: 34203929] (Human)		Human
M Tomori, T Nagamine, T Miyamoto, M Iha Effects of Ingesting Fucoidan Derived from Cladosiphon okamuranus Tokida on Human NK Cells: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Pilot Study Marine Drugs, 2021-06-15;19(6):. 2021-06-15 [PMID: 34203925] (Human)		Human
DPS Lopes, IS Ribeiro, DC Santos, FMS Lima, AA Santos, DSP Souza, DN Lopes, AO Prado, ÍS Pereira, DP Santos, GS Santos, RAA Silva Regular physical activity reduces the proinflammatory response in older women with diabetes and hypertension in the postmenopausal phase Experimental gerontology, 2021-06-11;152(0):111449. 2021-06-11 [PMID: 34126225] (Human)		Human
JA Jarrell, BJ Sytsma, LH Wilson, FL Pan, KHWJ Lau, GTS Kirby, AA Lievano, RS Pawell Numerical optimization of microfluidic vortex shedding for genome editing T cells with Cas9 Scientific Reports, 2021-06-03;11(1):11818. 2021-06-03 [PMID: 34083685] (Human)		Human
Y Jiang, AK Farrell, ET Tobin, HE Mair-Meije, DE Wildman, F Luca, RB Slatcher, S Zilioli Socioeconomic status, financial stress, and glucocorticoid resistance among youth with asthma: Testing the moderation effects of maternal involvement and warmth Brain, Behavior, and Immunity, 2021-05-17;0(0):. 2021-05-17 [PMID: 34015429] (Human)		Human
BK Jeong, JH Kim, MH Jung, KM Kang, YH Lee Cytokine Profiles of Non-Small Cell Lung Cancer Patients Treated with Concurrent Chemoradiotherapy with Regards to Radiation Pneumonitis Severity Journal of Clinical Medicine, 2021-02-11;10(4):. 2021-02-11 [PMID: 33670117] (Human)		Human
AM Aydin, M Hall, BL Bunch, H Branthoove, Z Sannasardo, A Mackay, M Beatty, AA Sarnaik, JE Mullinax, PE Spiess, S Pilon-Thom Expansion of tumor-infiltrating lymphocytes (TIL) from penile cancer patients International immunopharmacology, 2021-02-23;94(0):107481. 2021-02-23 [PMID: 33636562] (Human)		Human
Y Cheng, N Borcherdin, A Ogunsakin, CD Lemke-Milt, KN Gibson-Cor, A Rajan, AB Choi, W Wongpattar, CHF Chan, AK Salem, GJ Weiner, AL Simons The anti-tumor effects of cetuximab in combination with VTX-2337 are T cell dependent Scientific Reports, 2021-01-15;11(1):1535. 2021-01-15 [PMID: 33452311] (Human)		Human
Y Wang, M Mohseni, A Grauel, JE Diez, W Guan, S Liang, JE Choi, M Pu, D Chen, T Laszewski, S Schwartz, J Gu, L Mansur, T Burks, L Brodeur, R Velazquez, S Kovats, B Pant, G Buruzula, E Deng, JT Chen, F Sari-Sarra, C Dornelas, M Varadaraja, H Yu, C Liu, J Lim, HX Hao, X Jiang, A Malamas, MJ LaMarche, FC Geyer, M McLaughlin, C Costa, J Wagner, D Ruddy, P Jayaraman, ND Kirkpatric, P Zhang, O Iartchouk, K Aardalen, V Cremasco, G Dranoff, JA Engelman, S Silver, H Wang, WD Hastings, S Goldoni SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms Scientific Reports, 2021-01-14;11(1):1399. 2021-01-14 [PMID: 33446805] (Human)		Human
F Gaiani, S Graziano, F Boukid, B Prandi, L Bottarelli, A Barilli, A Dossena, N Marmiroli, M Gullì, GL de'Angelis, S Sforza The Diverse Potential of Gluten from Different Durum Wheat Varieties in Triggering Celiac Disease: A Multilevel In Vitro, Ex Vivo and In Vivo Approach Nutrients, 2020-11-20;12(11):. 2020-11-20 [PMID: 33233787] (Human)		Human
A Sa?kowska, I Karwaciak, K Kara?, J Dastych, M Ratajewski SARS-CoV-2 Proteins Induce IFNG in Th1 Lymphocytes Generated from CD4+ Cells from Healthy, Unexposed Polish Donors Vaccines (Basel), 2020-11-12;8(4):. 2020-11-12 [PMID: 33198287] (Human)		Human
A Sacchi, G Grassi, V Bordoni, P Lorenzini, E Cimini, R Casetti, E Tartaglia, L Marchioni, N Petrosillo, F Palmieri, G D'Offizi, S Notari, M Tempestill, MR Capobianch, E Nicastri, M Maeurer, A Zumla, F Locatelli, A Antinori, G Ippolito, C Agrati Early expansion of myeloid-derived suppressor cells inhibits SARS-CoV-2 specific T-cell response and may predict fatal COVID-19 outcome Cell Death Dis, 2020-10-27;11(10):921. 2020-10-27 [PMID: 33110074] (Human)		Human
K Yamashita, M Iwatsuki, N Yasuda-Yos, T Morinaga, Y Nakao, K Harada, K Eto, J Kurashige, Y Hiyoshi, T Ishimoto, Y Nagai, S Iwagami, Y Baba, Y Miyamoto, N Yoshida, JA Ajani, H Baba Trastuzumab upregulates programmed death ligand-1 expression through interaction with NK cells in gastric cancer Br J Cancer, 2020-10-26;0(0):. 2020-10-26 [PMID: 33100329] (Human)		Human
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Sun J, Fu F, Gu W, Yan R, Zhang G, Shen Z, Zhou Y, Wang H, Shen B, Zhang X Origination of new immunological functions in the costimulatory molecule B7-H3: the role of exon duplication in evolution of the immune system. PLoS ONE, 2011-09-13;6(9):e24751. 2011-09-13 [PMID: 21931843] (Human)		Human
Takei S, Hoshino T, Matsunaga K, Sakazaki Y, Sawada M, Oda H, Takenaka S, Imaoka H, Kinoshita T, Honda S, Ida H, Fukuda TA, Aizawa H Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis. Arthritis Res. Ther., 2011-03-24;13(2):R52. 2011-03-24 [PMID: 21435242] (Human)		Human
Jun AS, Cope L, Speck C, Feng X, Lee S, Meng H, Hamad A, Chakravarti S Subnormal cytokine profile in the tear fluid of keratoconus patients. PLoS ONE, 2011-01-27;6(1):e16437. 2011-01-27 [PMID: 21298010] (Human)		Human
Mulder DJ, Pooni A, Mak N, Hurlbut DJ, Basta S, Justinich CJ Antigen presentation and MHC class II expression by human esophageal epithelial cells: role in eosinophilic esophagitis. Am. J. Pathol., 2011-02-01;178(2):744-53. 2011-02-01 [PMID: 21281807] (Human)		Human
Brandau S, Trellakis S, Bruderek K, Schmaltz D, Steller G, Elian M, Suttmann H, Schenck M, Welling J, Zabel P, Lang S Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties. J. Leukoc. Biol., 2010-11-24;89(2):311-7. 2010-11-24 [PMID: 21106641] (Human)		Human
Song W, Tai YT, Tian Z, Hideshima T, Chauhan D, Nanjappa P, Exley MA, Anderson KC, Munshi NC HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells. Leukemia, 2010-11-19;25(1):161-8. 2010-11-19 [PMID: 21102427] (Human)		Human
Antonelli A, Ferri C, Ferrari SM, De Marco S, Di Domenicantonio A, Centanni M, Pupilli C, Villa E, Menichetti F, Fallahi P Interleukin-1beta, C-x-C motif ligand 10, and interferon-gamma serum levels in mixed cryoglobulinemia with or without autoimmune thyroiditis. J. Interferon Cytokine Res., 2010-10-07;30(11):835-42. 2010-10-07 [PMID: 20929277] (Human)		Human
Bachert C, Zhang N, Holtappels G, De Lobel L, Van Cauwenberge P, Liu S, Lin P, Bousquet J, Van Steen K Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma. J. Allergy Clin. Immunol., 2010-11-01;126(5):962. 2010-11-01 [PMID: 20810157] (Human)		Human
Zahn S, Rehkamper C, Kummerer BM, Ferring-Schmidt S, Bieber T, Tuting T, Wenzel J Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFN-lambda) in cutaneous lupus erythematosus. J. Invest. Dermatol., 2010-08-19;131(1):133-40. 2010-08-19 [PMID: 20720564] (Human)		Human
Zhang G, Wang J, Kelly J B7-h3 augments the inflammatory response and is associated with human sepsis. J. Immunol., 2010-08-09;185(6):3677-84. 2010-08-09 [PMID: 20696859] (Human)		Human
Beziat V, Nguyen S, Exley M, Achour A, Simon T, Chevallier P, Sirvent A, Vigouroux S, Debre P, Rio B, Vieillard V, Lubrano-Berthelier C, Alatrakchi N Shaping of iNKT cell repertoire after unrelated cord blood transplantation. Clin. Immunol., 2010-02-13;135(3):364-73. 2010-02-13 [PMID: 20153980] (Human)		Human
Rutanen J, Yaluri N, Modi S, Pihlajamaki J, Vanttinen M, Itkonen P, Kainulainen S, Yamamoto H, Lagouge M, Sinclair DA, Elliott P, Westphal C, Auwerx J, Laakso M SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity. Diabetes, 2010-01-27;59(4):829-35. 2010-01-27 [PMID: 20107110] (Human)		Human
Reeves EP, Williamson M, Byrne B, Bergin DA, Smith SG, Greally P, O'Kennedy R, O'Neill SJ, McElvaney NG IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis. J. Immunol., 2009-12-21;184(3):1642-52. 2009-12-21 [PMID: 20026745] (Human)		Human
Ogbomo H, Michaelis M, Altenbrandt B, Doerr HW, Cinatl J A novel immunomodulatory mechanism of ribavirin in suppressing natural killer cell function. Biochem. Pharmacol., 2009-08-07;79(2):188-97. 2009-08-07 [PMID: 19665449] (Human)		Human
Oh JY, Kim MK, Shin MS, Wee WR, Lee JH Cytokine secretion by human mesenchymal stem cells cocultured with damaged corneal epithelial cells. Cytokine, 2009-02-14;46(1):100-3. 2009-02-14 [PMID: 19223198] (Human)		Human
Rodriguez PC, Ernstoff MS, Hernandez C, Atkins M, Zabaleta J, Sierra R, Ochoa AC Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes. Cancer Res., 2009-02-05;69(4):1553-60. 2009-02-05 [PMID: 19201693] (Human)		Human
Mabilleau G, Sabokbar A Interleukin-32 promotes osteoclast differentiation but not osteoclast activation. PLoS ONE, 2009-01-12;4(1):e4173. 2009-01-12 [PMID: 19137064] (Human)		Human
Eyerich K, Pennino D, Scarponi C, Foerster S, Nasorri F, Behrendt H, Ring J, Traidl-Hoffmann C, Albanesi C, Cavani A IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response. J. Allergy Clin. Immunol., 2008-12-03;123(1):59-66.e4. 2008-12-03 [PMID: 19056110] (Human)		Human
Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J. Immunol., 2008-12-01;181(11):8053-67. 2008-12-01 [PMID: 19017998] (Human)		Human
Niederfuhr A, Kirsche H, Deutschle T, Poppert S, Riechelmann H, Wellinghausen N Staphylococcus aureus in nasal lavage and biopsy of patients with chronic rhinosinusitis. Allergy, 2008-10-01;63(10):1359-67. 2008-10-01 [PMID: 18782116] (Human)		Human
Yokoi T, Amakawa R, Tanijiri T, Sugimoto H, Torii Y, Amuro H, Son Y, Tajima K, Liu YJ, Ito T, Fukuhara S Mycobacterium bovis Bacillus Calmette-Guerin suppresses inflammatory Th2 responses by inducing functional alteration of TSLP-activated dendritic cells. Int. Immunol., 2008-08-13;20(10):1321-9. 2008-08-13 [PMID: 18703465] (Human)		Human
Djoba Siawaya JF, Roberts T, Babb C, Black G, Golakai HJ, Stanley K, Bapela NB, Hoal E, Parida S, van Helden P, Walzl G An evaluation of commercial fluorescent bead-based luminex cytokine assays. PLoS ONE, 2008-07-02;3(7):e2535. 2008-07-02 [PMID: 18596971] (Human)		Human
Liu TY, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, Ishihara O, Matsushita S Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells. Eur. J. Immunol., 2008-04-01;38(4):1012-23. 2008-04-01 [PMID: 18350544] (Human)		Human
Stefanescu R, Bassett D, Modarresi R, Santiago F, Fakruddin M, Laurence J Synergistic interactions between interferon-gamma and TRAIL modulate c-FLIP in endothelial cells, mediating their lineage-specific sensitivity to thrombotic thrombocytopenic purpura plasma-associated apoptosis. Blood, 2008-03-13;112(2):340-9. 2008-03-13 [PMID: 18339897] (Human)		Human
Mian MF, Lauzon NM, Stampfli MR, Mossman KL, Ashkar AA Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke. J. Leukoc. Biol., 2007-11-30;83(3):774-84. 2007-11-30 [PMID: 18055568] (Human)		Human
Petermann KB, Rozenberg GI, Zedek D, Groben P, McKinnon K, Buehler C, Kim WY, Shields JM, Penland S, Bear JE, Thomas NE, Serody JS, Sharpless NE CD200 is induced by ERK and is a potential therapeutic target in melanoma. J. Clin. Invest., 2007-12-01;117(12):3922-3929. 2007-12-01 [PMID: 18008004] (Human)		Human
Vidyarani M, Selvaraj P, Jawahar MS, Narayanan PR 1, 25 Dihydroxyvitamin D3 modulated cytokine response in pulmonary tuberculosis. Cytokine, 2007-10-29;40(2):128-34. 2007-10-29 [PMID: 17911026] (Human)		Human
Little RF, Aleman K, Kumar P, Wyvill KM, Pluda JM, Read-Connole E, Wang V, Pittaluga S, Catanzaro AT, Steinberg SM, Yarchoan R Phase 2 study of pegylated liposomal doxorubicin in combination with interleukin-12 for AIDS-related Kaposi sarcoma. Blood, 2007-09-10;110(13):4165-71. 2007-09-10 [PMID: 17846226] (Human)		Human
Frances R, Gonzalez-Navajas JM, Zapater P, Munoz C, Cano R, Pascual S, Santana F, Marquez D, Perez-Mateo M, Such J Translocation of bacterial DNA from Gram-positive microorganisms is associated with a species-specific inflammatory response in serum and ascitic fluid of patients with cirrhosis. Clin. Exp. Immunol., 2007-09-05;150(2):230-7. 2007-09-05 [PMID: 17822441] (Human)		Human
Lin YL, Liang YC, Chiang BL Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells. J. Leukoc. Biol., 2007-08-30;82(6):1473-80. 2007-08-30 [PMID: 17761954] (Human)		Human
Clay CC, Rodrigues DS, Ho YS, Fallert BA, Janatpour K, Reinhart TA, Esser U Neuroinvasion of fluorescein-positive monocytes in acute simian immunodeficiency virus infection. J. Virol., 2007-08-22;81(21):12040-8. 2007-08-22 [PMID: 17715237] (Primate - Macaca mulatta (Rhesus Macaque))		Primate - Macaca mulatta (Rhesus Macaque)
Seeber B, Sammel MD, Fan X, Gerton GL, Shaunik A, Chittams J, Barnhart KT Panel of markers can accurately predict endometriosis in a subset of patients. Fertil. Steril., 2007-08-13;89(5):1073-81. 2007-08-13 [PMID: 17706208] (Human)		Human
Irhimeh MR, Fitton JH, Lowenthal RM Fucoidan ingestion increases the expression of CXCR4 on human CD34+ cells. Exp. Hematol., 2007-06-01;35(6):989-94. 2007-06-01 [PMID: 17533053] (Human)		Human
Wolk K, Witte E, Hoffmann U, Doecke WD, Endesfelder S, Asadullah K, Sterry W, Volk HD, Wittig BM, Sabat R IL-22 induces lipopolysaccharide-binding protein in hepatocytes: a potential systemic role of IL-22 in Crohn's disease. J. Immunol., 2007-05-01;178(9):5973-81. 2007-05-01 [PMID: 17442982] (Human)		Human
Lee MT, Hooper LC, Kump L, Hayashi K, Nussenblatt R, Hooks JJ, Detrick B Interferon-beta and adhesion molecules (E-selectin and s-intracellular adhesion molecule-1) are detected in sera from patients with retinal vasculitis and are induced in retinal vascular endothelial cells by Toll-like receptor 3 signalling. Clin. Exp. Immunol., 2007-01-01;147(1):71-80. 2007-01-01 [PMID: 17177965] (Human)		Human
Ebert EC, Mehta V Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription. Cell. Immunol., 2006-08-17;241(1):7-13. 2006-08-17 [PMID: 16914126] (Human)		Human
Karrar A, Broome U, Uzunel M, Qureshi AR, Sumitran-Holgersson S Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction. Gut, 2006-07-13;56(2):243-52. 2006-07-13 [PMID: 16840505] (Human)		Human
Perryman LA, Blair JM, Kingsley EA, Szymanska B, Ow KT, Wen VW, MacKenzie KL, Vermeulen PB, Jackson P, Russell PJ Over-expression of p53 mutants in LNCaP cells alters tumor growth and angiogenesis in vivo. Biochem. Biophys. Res. Commun., 2006-05-11;345(3):1207-14. 2006-05-11 [PMID: 16723121] (Human)		Human
Wolk K, Witte E, Wallace E, Docke WD, Kunz S, Asadullah K, Volk HD, Sterry W, Sabat R IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur. J. Immunol., 2006-05-01;36(5):1309-23. 2006-05-01 [PMID: 16619290] (Human)		Human
Skoberne M, Somersan S, Almodovar W, Truong T, Petrova K, Henson PM, Bhardwaj N The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function. Blood, 2006-04-13;108(3):947-55. 2006-04-13 [PMID: 16614246] (Human)		Human
Claessens YE, Fontenay M, Pene F, Chiche JD, Guesnu M, Hababou C, Casadevall N, Dhainaut JF, Mira JP, Cariou A Erythropoiesis abnormalities contribute to early-onset anemia in patients with septic shock. Am. J. Respir. Crit. Care Med., 2006-03-30;174(1):51-7. 2006-03-30 [PMID: 16574939] (Human)		Human
Yoshikawa H, Sato K, Edahiro S, Furukawa Y, Maruta T, Iwasa K, Watanabe H, Takaoka S, Suzuki Y, Takamori M, Yamada M Elevation of IL-12 p40 and its antibody in myasthenia gravis with thymoma. J. Neuroimmunol., 2006-03-29;175(1):169-75. 2006-03-29 [PMID: 16574246] (Human)		Human
Hartl D, Latzin P, Zissel G, Krane M, Krauss-Etschmann S, Griese M Chemokines indicate allergic bronchopulmonary aspergillosis in patients with cystic fibrosis. Am. J. Respir. Crit. Care Med., 2006-03-16;173(12):1370-6. 2006-03-16 [PMID: 16543550] (Human)		Human
Kiryushko D, Pavon L, Novitskaya V, Sandoval-Lopez G, Soroka V, Eugenia Hernandez M, Klingelhofer J, Loria F, Lukanidin E, Estrada I, Berezin V, Perez M, Bock E, Moreno J, Avila U, Leff P, Anton B, Heinze G Th2 cytokine response in Major Depressive Disorder patients before treatment. J. Neuroimmunol., 2006-02-02;172(1):156-65. 2006-02-02 [PMID: 16457895] (Human)		Human
Yamanaka K, Clark R, Dowgiert R, Hurwitz D, Shibata M, Rich BE, Hirahara K, Jones DA, Eapen S, Mizutani H, Kupper TS Expression of interleukin-18 and caspase-1 in cutaneous T-cell lymphoma. Clin. Cancer Res., 2006-01-15;12(2):376-82. 2006-01-15 [PMID: 16428475] (Human)		Human
Hanabuchi S, Watanabe N, Wang YH, Ito T, Shaw J, Cao W, Qin FX, Liu YJ Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL). Blood, 2006-01-05;107(9):3617-23. 2006-01-05 [PMID: 16397134] (Human)		Human
von Strandmann EP, Hansen HP, Reiners KS, Schnell R, Borchmann P, Merkert S, Simhadri VR, Draube A, Reiser M, Purr I, Hallek M, Engert A A novel bispecific protein (ULBP2-BB4) targeting the NKG2D receptor on natural killer (NK) cells and CD138 activates NK cells and has potent antitumor activity against human multiple myeloma in vitro and in vivo. Blood, 2005-10-06;107(5):1955-62. 2005-10-06 [PMID: 16210338] (Human)		Human
Kristjansson S, Bjarnarson SP, Wennergren G, Palsdottir AH, Arnadottir T, Haraldsson A, Jonsdottir I Respiratory syncytial virus and other respiratory viruses during the first 3 months of life promote a local TH2-like response. J. Allergy Clin. Immunol., 2005-10-01;116(4):805-11. 2005-10-01 [PMID: 16210054] (Human)		Human
Mistchenko AS, Fornari MC, Viegas M, Barrero PR, Diez RA Detection of interleukin 10 in cerebrospinal fluid of patients with subacute sclerosing panencephalitis. J. Neurovirol., 2005-02-01;11(1):66-9. 2005-02-01 [PMID: 15804961] (Human)		Human
Takei M, Umeyama A, Arihara S, Matsumoto H Effect of piceatannol in human monocyte-derived dendritic cells in vitro. J Pharm Sci, 2005-05-01;94(5):974-82. 2005-05-01 [PMID: 15793803] (Human)		Human
Huang JL, Huang J, Duan ZH, Wei J, Min J, Luo XH, Li JG, Tan WP, Wu LZ, Liu RY, Li Y, Shao J, Huang BJ, Zeng YX, Huang W Th2 predominance and CD8+ memory T cell depletion in patients with severe acute respiratory syndrome. Microbes Infect., 2005-02-24;7(3):427-36. 2005-02-24 [PMID: 15784184] (Human)		Human
Kahlon KS, Brown C, Cooper LJ, Raubitschek A, Forman SJ, Jensen MC Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells. Cancer Res., 2004-12-15;64(24):9160-6. 2004-12-15 [PMID: 15604287] (Human)		Human
Jensen J, Krakauer M, Sellebjerg F Cytokines and adhesion molecules in multiple sclerosis patients treated with interferon-beta1b. Cytokine, 2005-01-07;29(1):24-30. 2005-01-07 [PMID: 15579375] (Human)		Human
Saeki S, Matsuse H, Kondo Y, Machida I, Kawano T, Tomari S, Obase Y, Fukushima C, Kohno S Effects of antiasthmatic agents on the functions of peripheral blood monocyte-derived dendritic cells from atopic patients. J. Allergy Clin. Immunol., 2004-09-01;114(3):538-44. 2004-09-01 [PMID: 15356554] (Human)		Human
Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R IL-22 increases the innate immunity of tissues. Immunity, 2004-08-01;21(2):241-54. 2004-08-01 [PMID: 15308104] (Human)		Human
Alter P, Maisch B Escape from cardiomyocyte apoptosis by enterovirus persistence due to elevated soluble Fas-receptors. Z Kardiol, 2004-07-01;93(7):524-32. 2004-07-01 [PMID: 15243763] (Human)		Human
Fieschi C, Bosticardo M, de Beaucoudrey L, Boisson-Dupuis S, Feinberg J, Santos OF, Bustamante J, Levy J, Candotti F, Casanova JL A novel form of complete IL-12/IL-23 receptor beta1 deficiency with cell surface-expressed nonfunctional receptors. Blood, 2004-06-03;104(7):2095-101. 2004-06-03 [PMID: 15178580] (Human)		Human
Garofalo RP, Hintz KH, Hill V, Ogra PL, Welliver RC Production of interferon gamma in respiratory syncytial virus infection of humans is not associated with interleukins 12 and 18. J. Med. Virol., 2004-06-01;73(2):289-94. 2004-06-01 [PMID: 15122806] (Human)		Human
Ciprandi G, Tosca MA, Milanese M, Caligo G, Ricca V Cytokines evaluation in nasal lavage of allergic children after Bacillus clausii administration: a pilot study. Pediatr Allergy Immunol, 2004-04-01;15(2):148-51. 2004-04-01 [PMID: 15059191] (Human)		Human
Basu S, Aballa TC, Ferrell SM, Lynne CM, Brackett NL Inflammatory cytokine concentrations are elevated in seminal plasma of men with spinal cord injuries. J. Androl., 2004-03-01;25(2):250-4. 2004-03-01 [PMID: 14760011] (Human)		Human
Durali D, de Goer de Herve MG, Giron-Michel J, Azzarone B, Delfraissy JF, Taoufik Y In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment. Blood, 2003-07-31;102(12):4084-9. 2003-07-31 [PMID: 12893768] (Human)		Human
Wu C, Sakorafas P, Miller R, McCarthy D, Scesney S, Dixon R, Ghayur T IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transduction. J. Immunol., 2003-06-01;170(11):5571-7. 2003-06-01 [PMID: 12759435] (Human)		Human
Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E, Noonan D, Albini A, Bernardi G, Mancardi GL, Battistini L, Uccelli A Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS. J. Leukoc. Biol., 2003-05-01;73(5):584-90. 2003-05-01 [PMID: 12714572] (Human)		Human
Hamzaoui K, Hamzaoui A, Guemira F, Bessioud M, Hamza M, Ayed K Cytokine profile in Behcet's disease patients. Relationship with disease activity. Scand. J. Rheumatol., 2002-01-01;31(4):205-10. 2002-01-01 [PMID: 12369651] (Human)		Human
D'Ambrosio D Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gamma delta T lymphocytes. Eur. J. Immunol., 2002-10-01;32(10):2934-43. 2002-10-01 [PMID: 12355447] (Human)		Human
Baroni A, Perfetto B, Ruocco E, Greco R, Criscuolo D, Ruocco V Cytokine pattern in blister fluid and sera of patients with pemphigus. Dermatology (Basel), 2002-01-01;205(2):116-21. 2002-01-01 [PMID: 12218224] (Human)		Human
Marme A, Strauss G, Bastert G, Grischke EM, Moldenhauer G Intraperitoneal bispecific antibody (HEA125xOKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma. Int. J. Cancer, 2002-09-10;101(2):183-9. 2002-09-10 [PMID: 12209996] (Human)		Human
Lazetic S, Leong SR, Chang JC, Ong R, Dawes G, Punnonen J Chimeric co-stimulatory molecules that selectively act through CD28 or CTLA-4 on human T cells. J. Biol. Chem., 2002-08-06;277(41):38660-8. 2002-08-06 [PMID: 12167647] (Human)		Human
Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, Pflanz S, Zhang R, Singh KP, Vega F, To W, Wagner J, O'Farrell AM, McClanahan T, Zurawski S, Hannum C, Gorman D, Rennick DM, Kastelein RA, de Waal Malefyt R, Moore KW A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R. J. Immunol., 2002-06-01;168(11):5699-708. 2002-06-01 [PMID: 12023369] (Human)		Human
Briard D, Brouty-Boye D, Azzarone B, Jasmin C Fibroblasts from human spleen regulate NK cell differentiation from blood CD34(+) progenitors via cell surface IL-15. J. Immunol., 2002-05-01;168(9):4326-32. 2002-05-01 [PMID: 11970974] (Human)		Human
Cotler SJ, Reddy KR, McCone J, Wolfe DL, Liu A, Craft TR, Ferris MW, Conrad AJ, Albrecht J, Morrissey M, Ganger DR, Rosenblate H, Blatt LM, Jensen DM, Taylor MW An analysis of acute changes in interleukin-6 levels after treatment of hepatitis C with consensus interferon. J. Interferon Cytokine Res., 2001-12-01;21(12):1011-9. 2001-12-01 [PMID: 11798458] (Human)		Human
Chen CD, Yang JH, Lin KC, Chao KH, Ho HN, Yang YS The significance of cytokines, chemical composition, and murine embryo development in hydrosalpinx fluid for predicting the IVF outcome in women with hydrosalpinx. Hum. Reprod., 2002-01-01;17(1):128-33. 2002-01-01 [PMID: 11756375] (Human)		Human
Jotwani R, 175, Palucka AK, Al-Quotub M, Nouri-Shirazi M, Kim J, Bell D, Banchereau J, Cutler CW Mature dendritic cells infiltrate the T cell-rich region of oral mucosa in chronic periodontitis: in situ, in vivo, and in vitro studies. 2001-10-15;167(8):4693-700. 2001-10-15 [PMID: 11591800] (Human)		Human
Albanesi C, Scarponi C, Sebastiani S, Cavani A, Federici M, Sozzani S, Girolomoni G A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases. J. Leukoc. Biol., 2001-10-01;70(4):617-23. 2001-10-01 [PMID: 11590199] (Human)		Human
Black , K P, Merrill , K W, Jackson , S, Katz , J Cytokine profiles in parotid saliva from HIV-1-infected individuals: changes associated with opportunistic infections in the oral cavity. Oral Microbiol Immunol, 2000-04-01;15(2):74-81. 2000-04-01 [PMID: 11155169] (Human)		Human
Rigano R, Profumo E, Bruschi F, Carulli G, Azzara A, Ioppolo S, Buttari B, Ortona E, Margutti P, Teggi A, Siracusano A Modulation of human immune response by Echinococcus granulosus antigen B and its possible role in evading host defenses. Infect. Immun., 2001-01-01;69(1):288-96. 2001-01-01 [PMID: 11119517] (Human)		Human
Kadowaki N, Antonenko S, Lau JY, Liu YJ Natural interferon alpha/beta-producing cells link innate and adaptive immunity. J. Exp. Med., 2000-07-17;192(2):219-26. 2000-07-17 [PMID: 10899908] (Human)		Human
Benson M, Strannegard IL, Wennergren G, Strannegard O Low levels of interferon-gamma in nasal fluid accompany raised levels of T-helper 2 cytokines in children with ongoing allergic rhinitis. Pediatr Allergy Immunol, 2000-02-01;11(1):20-8. 2000-02-01 [PMID: 10768732] (Human)		Human
Chen YM, Ting CC, Peng JW, Yang WK, Yang KY, Tsai CM, Perng RP Restoration of cytotoxic T lymphocyte function in malignant pleural effusion: interleukin-15 vs. interleukin-2. J. Interferon Cytokine Res., 2000-01-01;20(1):31-9. 2000-01-01 [PMID: 10670650] (Human)		Human
Yang C, Xiao L, Tongren JE, Sullivan J, Lal AA, Collins WE Cytokine production in rhesus monkeys infected with Plasmodium coatneyi. Am. J. Trop. Med. Hyg., 1999-08-01;61(2):226-9. 1999-08-01 [PMID: 10463671] (Primate)		Primate
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