Human Free IGFBP-1 Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. ALS (Acid Labile Subunit) is a liver-derived protein that exists in a ternary complex with Insulin-like Growth Factor (IGF)-binding Protein-3 (IGFBP-3) or IGFBP-5, and either IGF-I or IGF-II. ALS increases the half-life of IGF/IGFBP complexes in circulation.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 5 of 5.

Publications using DGB100	Applications	Species
Hivert, MF;White, F;Allard, C;James, K;Majid, S;Aguet, F;Ardlie, K;Edlow, A;Florez, J;Bouchard, L;Jacques, PE;Karumanchi, S;Powe, C; Placental RNA sequencing implicates IGFBP1 in insulin sensitivity during pregnancy and in gestational diabetes Research square 2023-10-27 [PMID: 37961187] (Human)		Human
Kamentseva, RS;Kharchenko, MV;Gabdrahmanova, GV;Kotov, MA;Kosheverova, VV;Kornilova, ES; EGF, TGF-? and Amphiregulin Differently Regulate Endometrium-Derived Mesenchymal Stromal/Stem Cells International journal of molecular sciences 2023-08-29 [PMID: 37686213] (Human)		Human
T Gorsek Spa, UR Markert, P Reif, W Schoell, G Moser, J Feichtinge, ZN Mihalic, J Kargl, CE Gargett, D Gold The fate of human SUSD2+ endometrial mesenchymal stem cells during decidualization Stem Cell Research, 2022-01-15;60(0):102671. 2022-01-15 [PMID: 35093718] (Human)		Human
DH Bak, MJ Choi, SR Kim, BC Lee, JM Kim, ES Jeon, W Oh, ES Lim, BC Park, MJ Kim, J Na, BJ Kim Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth Korean J. Physiol. Pharmacol., 2018-08-27;22(5):555-566. 2018-08-27 [PMID: 30181702] (Human)		Human
D Wu, F Kimura, L Zheng, M Ishida, Y Niwa, K Hirata, A Takebayash, A Takashima, K Takahashi, R Kushima, G Zhang, T Murakami Chronic endometritis modifies decidualization in human endometrial stromal cells Reprod. Biol. Endocrinol, 2017-03-04;15(1):16. 2017-03-04 [PMID: 28259137] (Human)		Human

Array DGB100

• IGFBP-1 Antibodies
• IGFBP-1 ELISA Kits
• IGFBP-1 Lysate
• IGFBP-1 Proteins
• IGFBP-1 ELISAs
• IGFBP-1 Proteins and Enzymes