IGFBP-1 Products

Description

IGFBP1 is a gene that codes for an IGF-binding protein that circulates in the plasma and prolongs the half-life of IGFs and works to either inhibit of stimulate the growth promoting effects while also promoting cell migration and has a length of 259 amino acids and a weight of approximately 28 kDa. Current studies are being done on several diseases and disorders relating to this gene including protein-energy malnutrition, pre-eclampsia, persistent fetal circulation syndrome, Silver-Russell syndrome, growth hormone deficiency, Ehlers-Danlos syndrome, glucose intolerance, Prader-Willi syndrome, and chronic fatigue syndrome. IGFBP1 has also been shown to have interactions with IGF1, IGF2, MMP26, TF, and ARNT in pathways such as the myometrial relaxation and contraction, HIF-1-alpha transcription factor, IGF regulation, and protein metabolism pathways.

Bioinformatics

Entrez	3484 Human
Uniprot	AAH35263.2 Human NM_000596 Human NP_000587 Human P08833 Human
Product By Gene ID	3484
Alternate Names	alpha-pregnancy-associated endometrial globulin amniotic fluid binding protein binding protein-25 binding protein-26 binding protein-28 growth hormone independent-binding protein hIGFBP-1 IBP1 IBP-1 IGF-binding protein 1 IGFBP-1 IGF-BP25 insulin-like growth factor binding protein 1 insulin-like growth factor-binding protein 1 Placental protein 12 PP12AFBP

Related IGFBP-1 Blog Posts

Check out the latest blog posts on IGFBP-1.

Detecting HIF alpha and beyond: Best controls for hypoxia Western blot analysis By Rosa Moreno, PhD. Detecting HIF alpha and beyond: Best controls for hypoxia Western blot analysisPhysiological low levels of oxygen induce normal hypoxic events across biological systems. This hypoxic state activ...    Read more.

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