Human FABP4 Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

FABP4 (Fatty Acid Binding Protein 4), also known as A-FABP and aP2, is the predominant FABP found in adipocytes and is often used as a marker for adipocyte differentiation. It is also expressed in macrophages, dendritic cells, and endothelial cells. FABP4 is a key mediator of intracellular fatty acid transport and metabolism in adipose tissue. Its expression is regulated by multiple factors including fatty acids, PPAR gamma agonists, and Insulin, and its levels increase with lipolytic stimulation. It can increase the hydrolytic activity of Hormone-Sensitive Lipase and increase the production of proinflammatory cytokines and chemokines. FABP4 upregulation in adipocytes and macrophages is associated with the development of Insulin resistance, hypertriacylglycerolaemia, and atherosclerosis. Serum levels of FABP4 are elevated in obesity and metabolic syndrome, type 2 diabetes, HIV-associated lipodystrophy, polycystic ovary syndrome, nonalcoholic fatty liver disease, atherosclerosis, and acute ischaemic stroke. FABP4 is also overexpressed in multiple cancer types including ovarian, bladder, glioblastoma, and oral, and it may play a role in tumor progression.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 10 of 14. Show All 14 Publications. Collapse Publications.

Publications using DFBP40	Applications	Species
Gu, Y;Avolio, E;Alvino, VV;Thomas, AC;Herman, A;Miller, PJ;Sullivan, N;Faulkner, A;Madeddu, P; The tyrosine kinase inhibitor Dasatinib reduces cardiac steatosis and fibrosis in obese, type 2 diabetic mice Cardiovascular diabetology 2023-08-17 [PMID: 37592236] (Human)		Human
H Svensson, S Einarsson, D Olausson, L Kluge, C Bergh, S Edén, M Lönn, A Thurin-Kje Inflammatory and metabolic markers in relation to outcome of in vitro fertilization in a cohort of predominantly overweight and obese women Scientific Reports, 2022-08-03;12(1):13331. 2022-08-03 [PMID: 35922472] (Human)		Human
K Miniewska, K Maliszewsk, K Pietrowska, J Godzie?, ? ?abieniec, M Mojsak, A Kr?towski, M Ciborowski PET/MRI-Evaluated Activation of Brown Adipose Tissue via Cold Exposure Impacts Lipid Metabolism Metabolites, 2022-05-19;12(5):. 2022-05-19 [PMID: 35629960] (Human)		Human
I Ron, RK Lerner, M Rathaus, R Livne, S Ron, E Barhod, R Hemi, A Tirosh, T Strauss, K Ofir, I Goldstein, IM Pessach, A Tirosh The adipokine FABP4 is a key regulator of neonatal glucose homeostasis JCI Insight, 2021-10-22;6(20):. 2021-10-22 [PMID: 34676825] (Human)		Human
H Wang, J Cao, JB Su, XQ Wang, X Wang, DM Zhang, XH Wang Serum fatty acid-binding protein 4 levels and responses of pancreatic islet &beta-cells and &alpha-cells in patients with type 2 diabetes Diabetology & metabolic syndrome, 2021-06-26;13(1):70. 2021-06-26 [PMID: 34174950] (Human)		Human
D Tsakogiann, E Kalogera, F Zagouri, E Zografos, D Balalis, G Bletsa Determination of FABP4, RBP4 and the MMP-9/NGAL complex in the serum of women with breast cancer Oncology Letters, 2020-12-04;21(2):85. 2020-12-04 [PMID: 33376518] (Human)		Human
T Sarabhai, S Kahl, J Szendroedi, DF Markgraf, OP Zaharia, C Barosa, C Herder, F Wickrath, P Bobrov, JH Hwang, JG Jones, M Roden Monounsaturated fat rapidly induces hepatic gluconeogenesis and whole-body insulin resistance JCI Insight, 2020-05-21;5(10):. 2020-05-21 [PMID: 32434996] (Human)		Human
YZ Chen, SQ Zhou, YQ Chen, H Peng, YG Zhuang Plasma Adipokines in Patients Resuscitated from Cardiac Arrest: Difference of Visfatin between Survivors and Nonsurvivors Dis. Markers, 2020-01-14;2020(0):9608276. 2020-01-14 [PMID: 32015774] (Human)		Human
S Numao, Y Nagasawa, N Goromaru, S Tamaki Comparison of plasma fatty acid binding protein 4 concentration in venous and capillary blood PLoS ONE, 2019-12-11;14(12):e0226374. 2019-12-11 [PMID: 31826012] (Human)		Human
J Patro-Ma?y, M Trojnar, ? Kimber-Tro, R Mierzy?ski, J Bartosiewi, J Oleszczuk, B Leszczy?sk FABP4 in Gestational Diabetes-Association between Mothers and Offspring J Clin Med, 2019-02-27;8(3):. 2019-02-27 [PMID: 30818771] (Human)		Human
O Huttala, M Palmroth, P Hemminki, T Toimela, T Heinonen, T Ylikomi, JR Sarkanen Development of Versatile Human In Vitro Vascularized Adipose Tissue Model with Serum-Free Angiogenesis and Natural Adipogenesis Induction Basic Clin. Pharmacol. Toxicol., 2018-04-27;0(0):. 2018-04-27 [PMID: 29443452] (Human)		Human
C Jahansouz, H Xu, AV Hertzel, S Kizy, KA Steen, R Foncea, FJ Serrot, N Kvalheim, G Luthra, K Ewing, DB Leslie, S Ikramuddin, DA Bernlohr Partitioning of adipose lipid metabolism by altered expression and function of PPAR isoforms after bariatric surgery Int J Obes (Lond), 2017-08-14;42(2):139-146. 2017-08-14 [PMID: 28894292] (Human)		Human
I Graupera, M Coll, E Pose, C Elia, S Piano, E Solà, D Blaya, P Huelin, C Solé, R Moreira, G de Prada, N Fabrellas, A Juanola, M Morales-Ru, P Sancho-Bru, C Villanueva, P Ginès Adipocyte Fatty-Acid Binding Protein is Overexpressed in Cirrhosis and Correlates with Clinical Outcomes Sci Rep, 2017-05-12;7(1):1829. 2017-05-12 [PMID: 28500294] (Human)		Human
Leryn J Reynolds Using Neonatal Skin to Study the Developmental Programming of Aging Exp. Gerontol, 2016-12-27;0(0):. 2016-12-27 [PMID: 28034763] (Human)		Human
Show All 14 Publications. Collapse Publications.

Array DFBP40

• FABP4/A-FABP Antibodies
• FABP4/A-FABP ELISA Kits
• FABP4/A-FABP Lysate
• FABP4/A-FABP Proteins
• FABP4/A-FABP ELISAs
• FABP4/A-FABP Proteins and Enzyme