Human Cathepsin L DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Cathepsin L is a lysosomal cysteine protease expressed in most eukaryotic cells. Cathepsin L is known to hydrolyze a number of proteins, including the proform of urokinase-type plasminogen activator, which is activated by Cathepsin L cleavage. Cathepsin L has also been shown to proteolytically inactivate a1-antitrypsin and secretory leucoprotease inhibitor, two major protease inhibitors of the respiratory tract.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 5 of 5.

Publications using DY952	Applications	Species
M Liu, AN Panagopoul, UM Oguz, S Samant, CH Vasa, DK Agrawal, YS Chatzizisi Role of triggering receptor expressed on myeloid cells-1 in the mechanotransduction signaling pathways that link low shear stress with inflammation Scientific Reports, 2023-03-21;13(1):4656. 2023-03-21 [PMID: 36944850] (Human)		Human
M Liu, S Samant, CH Vasa, RM Pedrigi, UM Oguz, S Ryu, T Wei, DR Anderson, DK Agrawal, YS Chatzizisi Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis PLoS ONE, 2023-01-20;18(1):e0280385. 2023-01-20 [PMID: 36662769] (Human)		Human
I Govorov, K Bremme, A Larsson, M Holmström, E Komlichenk, R Chaireti, M Mints Blood inflammatory and endothelial markers in women with von Willebrand disease PLoS ONE, 2019-01-10;14(1):e0210544. 2019-01-10 [PMID: 30629692] (Human)		Human
Rai S, Nejadhamzeeigilani Z, Gutowski N, Whatmore J Loss of the endothelial glycocalyx is associated with increased E-selectin mediated adhesion of lung tumour cells to the brain microvascular endothelium. J Exp Clin Cancer Res, 2015-09-25;34(0):105. 2015-09-25 [PMID: 26407999] (Human)		Human
Zhang Q, Wang W, Li J, Yang N, Chen G, Wang Z, Liang Z Cathepsin L suppression increases the radiosensitivity of human glioma U251 cells via G2/M cell cycle arrest and DNA damage. Acta Pharmacol Sin, 2015-06-22;36(9):1113-25. 2015-06-22 [PMID: 26095040] (Human)		Human

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