Mouse/Rat Cystatin C Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Cystatin C is a secreted cysteine protease inhibitor that inhibits Cathepsins B, H, K, L, and S. Cystatin C serum concentration correlates closely to the glomerular filtration rate (GFR); elevated levels are associated with coronary artery and cardiovascular disease risk. Dysregulation of Cystatin C can modulate tumor growth and metastasis. In humans, the L68Q variant forms dimers and oligomers more easily than wild type protein and is the cause for hereditary Cystatin C amyloid angiopathy.

We have publications tested in 2 confirmed species: Mouse, Rat.

We have publications tested in 1 application: ELISA Capture.

Showing Publications 1 - 10 of 34. Show All 34 Publications. Collapse Publications.

Publications using MSCTC0	Applications	Species
Rauckhorst, AJ;Vasquez Martinez, G;Mayoral Andrade, G;Wen, H;Kim, JY;Simoni, A;Robles-Planells, C;Mapuskar, KA;Rastogi, P;Steinbach, EJ;McCormick, ML;Allen, BG;Pabla, NS;Jackson, AR;Coleman, MC;Spitz, DR;Taylor, EB;Zepeda-Orozco, D; Tubular mitochondrial pyruvate carrier disruption elicits redox adaptations that protect from acute kidney injury Molecular metabolism 2023-12-07 [PMID: 38056691] (Mouse)		Mouse
Rega, LR;Janssens, V;Graversen, JH;Moestrup, SK;Cairoli, S;Goffredo, BM;Nevo, N;Courtoy, GE;Jouret, F;Antignac, C;Emma, F;Pierreux, CE;Courtoy, PJ; Dietary supplementation of cystinotic mice by lysine inhibits the megalin pathway and decreases kidney cystine content Scientific reports 2023-10-12 [PMID: 37828038] (Mouse)		Mouse
Han, DS;Erickson, C;Hansen, KC;Kirkbride-Romeo, L;He, Z;Rodell, CB;Soranno, DE; Mesenchymal Stem Cells Delivered Locally to Ischemia-Reperfused Kidneys via Injectable Hyaluronic Acid Hydrogels Decrease Extracellular Matrix Remodeling 1 Month after Injury in Male Mice Cells 2023-07-04 [PMID: 37443806] (Mouse)		Mouse
AJ Rauckhorst, GV Martinez, GM Andrade, H Wen, JY Kim, A Simoni, KA Mapuskar, P Rastogi, EJ Steinbach, ML McCormick, BG Allen, NS Pabla, AR Jackson, MC Coleman, DR Spitz, EB Taylor, D Zepeda-Oro Tubular Mitochondrial Pyruvate Carrier Disruption Elicits Redox Adaptations that Protect from Acute Kidney Injury bioRxiv : the preprint server for biology, 2023-01-31;0(0):. 2023-01-31 [PMID: 36778297] (Mouse)		Mouse
MY Chang, SH Hsu, LY Ma, LF Chou, CC Hung, YC Tian, CW Yang Effects of Suramin on Polycystic Kidney Disease in a Mouse Model of Polycystin-1 Deficiency International Journal of Molecular Sciences, 2022-07-31;23(15):. 2022-07-31 [PMID: 35955634] (Mouse)		Mouse
Y Zhu, LGPL Prata, EOW Gerdes, JME Netto, T Pirtskhala, N Giorgadze, U Tripathi, CL Inman, KO Johnson, A Xue, AK Palmer, T Chen, K Schaefer, JN Justice, AM Nambiar, N Musi, SB Kritchevsk, J Chen, S Khosla, D Jurk, MJ Schafer, T Tchkonia, JL Kirkland Orally-active, clinically-translatable senolytics restore alpha-Klotho in mice and humans EBioMedicine, 2022-03-13;0(0):103912. 2022-03-13 [PMID: 35292270] (Mouse)		Mouse
R Harwood, J Bridge, L Ressel, L Scarfe, J Sharkey, G Czanner, PA Kalra, A Odudu, S Kenny, B Wilm, P Murray Murine models of renal ischemia reperfusion injury: An opportunity for refinement using noninvasive monitoring methods Physiological Reports, 2022-03-01;10(5):e15211. 2022-03-01 [PMID: 35266337] (Mouse)		Mouse
MJ Uddin, J Jeong, ES Pak, H Ha CO-Releasing Molecule-2 Prevents Acute Kidney Injury through Suppression of ROS-Fyn-ER Stress Signaling in Mouse Model Oxidative Medicine and Cellular Longevity, 2021-07-06;2021(0):9947772. 2021-07-06 [PMID: 34326922] (Mouse)		Mouse
ES Pak, MJ Uddin, H Ha Inhibition of Src Family Kinases Ameliorates LPS-Induced Acute Kidney Injury and Mitochondrial Dysfunction in Mice Int J Mol Sci, 2020-11-03;21(21):. 2020-11-03 [PMID: 33153232] (Mouse)		Mouse
ME Abouelela, MAA Orabi, RA Abdelhamid, MS Abdelkader, HR Madkor, FMM Darwish, T Hatano, BEM Elsadek Ethyl acetate extract of Ceiba pentandra (L.) Gaertn. reduces methotrexate-induced renal damage in rats via antioxidant, anti-inflammatory, and antiapoptotic actions Journal of traditional and complementary medicine, 2019-08-28;10(5):478-486. 2019-08-28 [PMID: 32953564] (Rat)		Rat
K Kohl, E Herzog, G Dickneite, S Pestel Evaluation of urinary biomarkers for early detection of acute kidney injury in a rat nephropathy model J Pharmacol Toxicol Methods, 2020-08-07;0(0):106901. 2020-08-07 [PMID: 32771565] (Rat)		Rat
Y Mizunuma, K Kanasaki, K Nitta, Y Nakamura, Y Ishigaki, Y Takagaki, M Kitada, S Li, H Liu, J Li, I Usui, Y Aso, D Koya CD-1db/db mice: a novel type 2 diabetic mouse model with progressive kidney fibrosis J Diabetes Investig, 2020-07-03;0(0):. 2020-07-03 [PMID: 32472621] (Mouse)		Mouse
S Kashyap, KZ Hein, CC Chini, J Lika, GM Warner, LK Bale, VE Torres, PC Harris, C Oxvig, CA Conover, EN Chini Metalloproteinase PAPP-A regulation of IGF-1 contributes to polycystic kidney disease pathogenesis JCI Insight, 2020-02-27;0(0):. 2020-02-27 [PMID: 31990681] (Mouse)		Mouse
MM Perales-Qu, AL Saucedo, JR Lucio-Guti, N Waksman, G Alarcon-Ga, G Govea-Torr, C Sanchez-Ma, E Pérez-Rodr, FJ Guzman-de, P Cordero-Pé Metabolomic and biochemical characterization of a new model of the transition of acute kidney injury to chronic kidney disease induced by folic acid PeerJ, 2019-06-21;7(0):e7113. 2019-06-21 [PMID: 31275747] (Rat)		Rat
CL Lin, YC Hsu, YT Huang, YH Shih, CJ Wang, WC Chiang, PJ Chang A KDM6A-KLF10 reinforcing feedback mechanism aggravates diabetic podocyte dysfunction EMBO Mol Med, 2019-05-01;11(5):. 2019-05-01 [PMID: 30948420] (Mouse)		Mouse
SP Srivastava, J Li, M Kitada, H Fujita, Y Yamada, JE Goodwin, K Kanasaki, D Koya SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis Cell Death Dis, 2018-09-24;9(10):997. 2018-09-24 [PMID: 30250024] (Mouse)		Mouse
K Czarzasta, A Cudnoch-Je, L Niemczyk, R Wrzesien, M Tkaczyk, L Puchalska, M Saracyn, W Zmudzki, S Niemczyk Effect of Chronic Kidney Disease on Changes in Vasopressin System Expression in the Kidney Cortex in Rats with Nephrectomy Biomed Res Int, 2018-06-14;2018(0):2607928. 2018-06-14 [PMID: 30013980] (Rat)		Rat
MKE Ougaard, PH Kvist, HE Jensen, C Hess, I Rune, H Søndergaar Murine Nephrotoxic Nephritis as a Model of Chronic Kidney Disease Int J Nephrol, 2018-03-05;2018(0):8424502. 2018-03-05 [PMID: 29692933] (Mouse)		Mouse
K Yoshikawa, M Iwasa, A Eguchi, S Kojima, N Yoshizawa, M Tempaku, R Sugimoto, N Yamamoto, K Sugimoto, Y Kobayashi, H Hasegawa, Y Takei Neutrophil gelatinase-associated lipocalin level is a prognostic factor for survival in rat and human chronic liver diseases Hepatol Commun, 2017-10-16;1(9):946-956. 2017-10-16 [PMID: 29404502] (ELISA Capture, Rat)	ELISA Capture	Rat
A Bienholz, R Mae Pang, H Guberina, U Rauen, O Witzke, B Wilde, F Petrat, T Feldkamp, A Kribben Resveratrol Does Not Protect from Ischemia-Induced Acute Kidney Injury in an in Vivo Rat Model Kidney Blood Press. Res., 2017-12-05;42(6):1090-1103. 2017-12-05 [PMID: 29207388] (Rat)		Rat
S Tsuji, M Sugiura, S Tsutsumi, H Yamada Sex differences in the excretion levels of traditional and novel urinary biomarkers of nephrotoxicity in rats J Toxicol Sci, 2017-01-01;42(5):615-627. 2017-01-01 [PMID: 28904297] (Rat)		Rat
SL Walton, H Bielefeldt, RR Singh, J Li, TM Paravicini, MH Little, KM Moritz Prenatal hypoxia leads to hypertension, renal renin-angiotensin system activation and exacerbates salt-induced pathology in a sex-specific manner Sci Rep, 2017-08-15;7(1):8241. 2017-08-15 [PMID: 28811528] (Mouse)		Mouse
D Jensen, C Kierulf-La, MLV Kristensen, R Nørregaard, K Weyer, R Nielsen, EI Christense, H Birn Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats PLoS ONE, 2017-06-02;12(6):e0178796. 2017-06-02 [PMID: 28575050] (Mouse, Rat)		Mouse, Rat
ME Turner, KJ Laverty, PS Jeronimo, M Kaufmann, G Jones, CA White, RM Holden, MA Adams Validation of a routine two-sample iohexol plasma clearance assessment of GFR and an evaluation of common endogenous markers in a rat model of CKD Physiol Rep, 2017-05-01;5(9):. 2017-05-01 [PMID: 28483858] (Rat)		Rat
TJ Pianta, JW Pickering, L Succar, M Chin, T Davidson, NA Buckley, F Mohamed, ZH Endre Dexamethasone Modifies Cystatin C-Based Diagnosis of Acute Kidney Injury During Cisplatin-Based Chemotherapy Kidney Blood Press. Res, 2017-03-17;42(1):62-75. 2017-03-17 [PMID: 28315878] (Rat)		Rat
R Watanabe, JI Suzuki, K Wakayama, Y Maejima, M Shimamura, H Koriyama, H Nakagami, H Kumagai, Y Ikeda, H Akazawa, R Morishita, I Komuro, M Isobe A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction Sci Rep, 2017-03-07;7(0):43920. 2017-03-07 [PMID: 28266578] (Rat)		Rat
Obesity-induced kidney injury is attenuated by amelioration of aberrant PHD2 activation in proximal tubules Sci Rep, 2016-11-09;6(0):36533. 2016-11-09 [PMID: 27827416] (Mouse)		Mouse
Discordance in cathepsin B and cystatin C expressions in bronchoalveolar fluids between murine bleomycin-induced fibrosis and human idiopathic fibrosis Respir Res, 2016-09-22;17(1):118. 2016-09-22 [PMID: 27658724] (Mouse)		Mouse
Effect of Antifibrotic MicroRNAs Crosstalk on the Action of N-acetyl-seryl-aspartyl-lysyl-proline in Diabetes-related Kidney Fibrosis Sci Rep, 2016-07-18;6(0):29884. 2016-07-18 [PMID: 27425816] (Mouse)		Mouse
DH Kim, BH Choi, SK Ku, JH Park, E Oh, MK Kwak Beneficial Effects of Sarpogrelate and Rosuvastatin in High Fat Diet/Streptozotocin-Induced Nephropathy in Mice PLoS ONE, 2016-04-20;11(4):e0153965. 2016-04-20 [PMID: 27097221] (Mouse)		Mouse
Nozako M, Koyama T, Nagano C, Sato M, Matsumoto S, Mitani K, Yasufuku R, Kohashi M, Yoshikawa T An Atherogenic Paigen-Diet Aggravates Nephropathy in Type 2 Diabetic OLETF Rats. PLoS ONE, 2015-11-25;10(11):e0143979. 2015-11-25 [PMID: 26606054] (Rat)		Rat
Wu J, Cheng Z, Gu Y, Zou W, Zhang M, Zhu P, Hu S Aggravated Cardiac Remodeling post Aortocaval Fistula in Unilateral Nephrectomized Rats. PLoS ONE, 2015-08-07;10(8):e0134579. 2015-08-07 [PMID: 26252578] (Rat)		Rat
Shi S, Srivastava S, Kanasaki M, He J, Kitada M, Nagai T, Nitta K, Takagi S, Kanasaki K, Koya D Interactions of DPP-4 and integrin beta1 influences endothelial-to-mesenchymal transition. Kidney Int, 2015-04-01;88(3):479-89. 2015-04-01 [PMID: 25830763] (Mouse)		Mouse
Kong H, Chen F, He Y, Wu L, Wang L, Zhu S, Zheng S Intrarenal resistance index for the assessment of acute renal injury in a rat liver transplantation model. BMC Nephrol, 2013-03-02;14(0):55. 2013-03-02 [PMID: 23453043] (Rat)		Rat
Show All 34 Publications. Collapse Publications.

Array MSCTC0

• Cystatin C Antibodies
• Cystatin C Antibody Pair
• Cystatin C ELISA Kit
• Cystatin C Lysate
• Cystatin C Proteins
• Cystatin C Proteins and Enzymes
• Cystatin C ELISAs