Plexin B1 Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Plexin B1 is a type I transmembrane protein that belongs to the Plexin family of semaphorin receptors. It is derived from a single peptide that undergoes proteolytic processing in its extracellular domain to form the non-covalently-linked heterodimer of the extracellular alpha subunit and the transmembrane beta subunit. Human Plexin B1 extracellular alpha subunit shares homology with semaphorins, HGF receptor and MSP receptor and contains a sema domain and three IPT/TIG domains. It functions as a receptor for semaphorin 4D/CD100. Multiple splice isoforms of Plexin B1 have been reported. Within the region used as immunogen, human Plexin B1 shares 90% and 97% amino acid sequence homology with mouse and canine Plexin B1, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: IHC-P, Immunoprecipitation, Western Blot.

Showing Publications 1 - 6 of 6.

Publications using AF3749	Applications	Species
Yong Huang, Rut Tejero, Vivian K. Lee, Concetta Brusco, Theodore Hannah, Taylor B. Bertucci et al. Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics Communications Biology 2021-01-29 [PMID: 33514835]
Tianliang Sun A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib J. Cell Biol, 2016-12-22;0(0):. 12/22/2016 [PMID: 28007914]
Zielonka M, Krishnan R, Swiercz J, Offermanns S The IkappaB kinase complex is required for plexin-B-mediated activation of RhoA. PLoS ONE, 2014-08-19;9(8):e105661. 2014-08-19 [PMID: 25137062] (Immunoprecipitation, Human)	Immunoprecipitation	Human
Sun , Tianlian, Krishnan , Rameshku, Swiercz , Jakub M Grb2 mediates semaphorin-4D-dependent RhoA inactivation. J Cell Sci, 2012-04-14;125(0):3557-67. 2012-04-14 [PMID: 22505611] (Western Blot, Human)	Western Blot	Human
Worzfeld T, Swiercz JM, Looso M ErbB-2 signals through Plexin-B1 to promote breast cancer metastasis. J. Clin. Invest., 2012-03-01;122(4):1296-305. 2012-03-01 [PMID: 22378040] (IHC-P, Human)	IHC-P	Human
Swiercz JM, Worzfeld T, Offermanns S ErbB-2 and met reciprocally regulate cellular signaling via plexin-B1. J. Biol. Chem., 2007-11-19;283(4):1893-901. 2007-11-19 [PMID: 18025083] (Immunoprecipitation, Western Blot, Human)	Immunoprecipitation, Western Blot	Human

Array AF3749

• Plexin B1 Antibodies
• Plexin B1 Lysate
• Plexin B1 Protein
• Plexin B1 Proteins and Enzymes