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HTRA2/Omi Antibody (ST54-05)

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Western Blot: HTRA2/Omi Antibody (ST54-05) [NBP2-67543] - Analysis of HtrA2 on 293 cell lysates using anti-HtrA2 antibody at 1/1,000 dilution.
Western Blot: HTRA2/Omi Antibody (ST54-05) [NBP2-67543] - Analysis of HtrA2 on 293 cell lysates using anti-HtrA2 antibody at 1/1,000 dilution.
Immunohistochemistry-Paraffin: HTRA2/Omi Antibody (ST54-05) [NBP2-67543] - Analysis of paraffin-embedded mouse liver tissue using anti-HtrA2 antibody. Counter stained with hematoxylin.
Immunohistochemistry-Paraffin: HTRA2/Omi Antibody (ST54-05) [NBP2-67543] - Analysis of paraffin-embedded human colon cancer tissue using anti-HtrA2 antibody. Counter stained with hematoxylin.
Immunohistochemistry-Paraffin: HTRA2/Omi Antibody (ST54-05) [NBP2-67543] - Analysis of paraffin-embedded human liver tissue using anti-HtrA2 antibody. Counter stained with hematoxylin.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IP
Clone
ST54-05
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

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HTRA2/Omi Antibody (ST54-05) Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Recombinant protein within Human HTRA2/Omi aa 800-188 / 458. (SwissProt: O43464 Human; SwissProt: Q9JIY5 Mouse; Unigene: 107325 Rat)
Localization
Mitochondrion intermembrane space, Mitochondrion membrane.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
HTRA2
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Immunoprecipitation
  • Western Blot 1:1000-1:2000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
TBS (pH7.4), 0.05% BSA, 40% Glycerol
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for HTRA2/Omi Antibody (ST54-05)

  • High temperature requirement protein A2
  • HtrA serine peptidase 2
  • HTRA2
  • HtrA-like serine protease
  • Omi
  • OMIOmi stress-regulated endoprotease
  • PARK13EC 3.4.21.108
  • PRSS25
  • PRSS25serine, 25
  • Serine protease 25
  • serine protease HTRA2, mitochondrial
  • Serine proteinase OMI

Background

HtrA2 (Omi) is a serine protease that plays a significant role in programmed cell death, or apoptosis. Localized to the intermembrane space of the mitochondria, HtrA2 exists predominantly as two isoforms (1). In response to cellular stress signals, HtrA2 is released into the cytosol. One way that HtrA2 induces apoptosis is by binding to BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), and thereby inhibiting their caspase-inhibitory activity (2,3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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HTRA2/Omi Antibody
(ST54-05)
NBP2-67543
HTRA2/Omi Antibody (ST54-05)
Species: Hu, Mu, Rt
Applications: WB, IHC, IP

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Bioinformatics

Gene Symbol HTRA2