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Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody

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Immunohistochemistry-Paraffin: Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody [NBP1-91982] - Staining of human testis shows strong granular cytoplasmic positivity in Leydig cells.
Immunohistochemistry-Paraffin: Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody [NBP1-91982] - Staining of human cerebral cortex shows granular cytoplasmic positivity in neuronal cells.
Immunohistochemistry-Paraffin: Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody [NBP1-91982] - Staining of human cerebral cortex shows moderate granular cytoplasmic positivity in neurons.
Immunohistochemistry-Paraffin: Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody [NBP1-91982] - Staining of human kidney shows moderate granular cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody [NBP1-91982] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: NQIQKLEESRSKLERAIARHEVREIEQRHTMDGPRQDATLDEEEDMVIIYNRVPKTASTSFTNIAYDLCAKNKYHVLH
Predicted Species
Mouse (95%), Rat (96%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HS2ST1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Protein (NBP1-91982PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1 Antibody

  • 2OST
  • 2-O-sulfotransferase
  • EC 2.8.2
  • EC 2.8.2.-
  • FLJ11317
  • heparan sulfate 2-O-sulfotransferase 1
  • HS2ST
  • HS2ST1
  • KIAA0448dJ604K5.2
  • MGC131986

Background

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes heparan sulfate 2-O-sulfotransferase, a member of the heparan sulfate biosynthetic enzyme family. This family member transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HS2ST1