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GPR39 Antibody [DyLight 650]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 650

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 405
NLS142AF405
Alexa Fluor 488
NLS142AF488
Alexa Fluor 647
NLS142AF647
Alexa Fluor 700
NLS142AF700
Biotin
NLS142B
DyLight 405
NLS142V
DyLight 488
NLS142G
DyLight 550
NLS142R
FITC
NLS142F
Unconjugated
NLS142
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NLS142
BSA Free
NLS142SS
BSA Free
NLS142
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GPR39 Antibody [DyLight 650] Summary

Immunogen
A synthetic peptide made to an internal region of the human GPR39 protein (within residues 400-500). [Swiss-Prot O43194]
Localization
Cell membrane; Multi-pass membrane protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GPR39
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50
  • Immunohistochemistry-Paraffin 1:50
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 25604641)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for GPR39 Antibody [DyLight 650]

  • G protein-coupled receptor 39
  • GPR39
  • G-protein coupled receptor 39
  • MGC149541

Background

G protein-coupled receptor 39 is an important receptor in the Ghrelin family pathway, and plays an important role in hypertension and adipogenesis. When obestatin binds GPR39, vasodilation occurs in the heart and pancreas, as an effect of pituitary growth hormone effects there. This reaction seems to be protective in these tissues and decreases the effects of diabetes and hypercholesterolemia. However, overexpression of GPR39 is implicated in the formation of squamous cell carcinoma in the esophagus. In this cancer, metastases have inordinately high levels of GPR39.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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GPR39 Antibody
[DyLight 650]
NLS142C
GPR39 Antibody [DyLight 650]
Species: Hu, Mu
Applications: IHC

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Bioinformatics

Gene Symbol GPR39