Frizzled-1 Antibody (162531) [mFluor Violet 450 SE] Summary
Immunogen |
Mouse myeloma cell line NS0-derived recombinant mouse Frizzled‑1 Gln72-His248 (Met122Ile) Accession # O70421 |
Specificity |
Detects mouse Frizzled-1 in
direct ELISAs and Western blots. Detects human Frizzled-1 in Flow Cytometry.
In direct ELISAs, approximately 30% cross‑reactivity with recombinant mouse
(rm) Frizzled-9 is observed and no cross-reactivity with recombinant human (rh)
Frizzled-5, rmFrizzled 2, 3, 4, 6, 7, 8, or rhMFRP is observed. No staining is observed on normal human PBMCs.
|
Isotype |
IgG2a |
Clonality |
Monoclonal |
Host |
Rat |
Gene |
FZD1 |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- CyTOF-ready
- Flow Cytometry
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Notes
mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Alternate Names for Frizzled-1 Antibody (162531) [mFluor Violet 450 SE]
Background
FZD1 is a widely expressed Frizzled Receptor that mediates Wnt signaling. FZD1 expression has been reported in heart, kidney, lung, ovary, pancreas, placenta, and prostate. ESTs have been isolated from brain, embryo, eye, heart, heart/melanocyte/uterus, kidney, liver/spleen, lung, prostate, skin, and uterus libraries.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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