Wnt-1 Antibody (10C8) - BSA Free

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt1 (Wingless-type MMTV integration site family member 1) is a member of the WNT gene family. It is highly conserved in evolution and the protein encoded by this gene is known to be 98% identical to mouse Wnt1 protein at the amino acid level. Studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. Wnt1 is secreted as an extracellular matrix protein.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: IF/IHC, IHC, IHC-P.

Showing Publications 1 - 2 of 2.

Publications using NBP1-51575	Applications	Species
Karata? A, �merciko?lu Z, �z B et al. Wnt signaling pathway activities may be altered in primary Sjogren�s syndrome TURKISH JOURNAL OF MEDICAL SCIENCES 2021-08-30 [PMID: 34058801] (IHC, IHC-P)	IHC, IHC-P
Ardiana D, Herwanto N, Prakoeswa CR, Agusni I Expression of WNT1 signalling proteins after phototherapy exposure in vitiligo Journal of Pakistan Association of Dermatologists 2019-01-01 (IF/IHC, Human)	IF/IHC	Human

Array NBP1-51575

• Wnt-1 Antibodies
• Wnt-1 Lysate
• Wnt-1 Proteins and Enzymes