Exosome Component 9 Antibody - BSA Free

Manufactured by Genomic Antibody Technology™. GAT FAQs

Exosome component 9 is part of the 3' -> 5' exoribonuclease complex that helps to degrade unstable mRNA. It binds to ARE-containing RNAs and performs 3' end trimming and degradation. These activities lead toward the maturation of RNA into more stable forms, which then become involved in transcription and translation. In the related Arabidopsis equivalent, loss of function of this protein is a lethal mutation. In ruminants, EXOSC9 is differentially expressed throughout the gut at different stages of development. EXOSC9 seems to be important in the degradation of histone mRNA and may be important in some downstream epigenetic effects.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Chicken.

We have publications tested in 2 applications: Chemotaxis, WB.

Showing Publications 1 - 4 of 4.

Publications using NBP1-71702	Applications	Species
McIver SC, Katsumura KR, Davids E et al. Exosome complex orchestrates developmental signaling to balance proliferation and differentiation during erythropoiesis. Elife. 2016-08-20 [PMID: 27543448] (Chemotaxis, Mouse)	Chemotaxis	Mouse
Morales JC, Richard P, Patidar PL et al. XRN2 Links Transcription Termination to DNA Damage and Replication Stress PLoS Genet. 2016-07-01 [PMID: 27437695]
Hsin JP, Li W, Hoque M et al. RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells. Elife (Cambridge) 2014-06-04 [PMID: 24842995] (WB, Chicken) Details: EXOSC3 antibody used for WB on lysates of 26r (DT40 cells derived Rpb1 derivative containing a CTD with 26 YSPTSPS repeats) and 25F+Y cells (Rpb1-Y1F derivative in which only a single F, in the C terminal-most heptad, was changed back to Y). WB data shown in Supplement Figure 4.	WB	Chicken
Richard P, Feng S, Manley JL. A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage. Genes Dev. 2013-10-15 [PMID: 24105744] (WB, Human)	WB	Human

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: Hsin Jing-Ping	WB	Other	10/18/2013	View Summary Application Western Blot Species Other
Enlarge	5 reviewed by: Patricia Richard	IP	Human	08/02/2012	View Summary Application Immunoprecipitation Sample Tested HeLa, U87 whole cell extract and nuclear extract Species Human Lot A1

Array NBP1-71702

• Exosome Component 9 Antibodies
• Exosome Component 9 Lysate
• Exosome Component 9 Proteins