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Exosome Component 9 Antibody [HRP]

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Product Details

Summary
Reactivity Hu, Mu, Ch, BvSpecies Glossary
Applications WB, Simple Western, ChIP, ICC/IF, IHC, IP, ChIP
Clonality
Polyclonal
Host
Rabbit
Conjugate
HRP

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Exosome Component 9 Antibody [HRP] Summary

Immunogen
A genomic peptide made to an internal region of human Exosome Component 9 (within residues 250-439). [Swiss-Prot Q06265]
Localization
Cytoplasm. Nucleus - nucleolus.
Predicted Species
Bovine (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EXOSC9
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Chromatin Immunoprecipitation (ChIP)
  • Chromatin Immunoprecipitation
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Readout System

Reactivity Notes

Immunogen has 83% identity to rat and 90% identity to bovine.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for Exosome Component 9 Antibody [HRP]

  • Autoantigen PM/Scl 1
  • EC 3.1.13
  • exosome complex component RRP45
  • exosome complex exonuclease RRP45
  • P5
  • p6
  • P75 polymyositis-scleroderma overlap syndrome associated autoantigen
  • PCH1D
  • PM/Scl-75
  • PMSCL autoantigen, 75kD
  • PMSCL1
  • polymyositis/scleroderma autoantigen 1 (75kD)
  • Polymyositis/scleroderma autoantigen 1
  • polymyositis/scleroderma autoantigen 1, 75kDa
  • RRP45
  • Rrp45p

Background

Exosome component 9 is part of the 3' -> 5' exoribonuclease complex that helps to degrade unstable mRNA. It binds to ARE-containing RNAs and performs 3' end trimming and degradation. These activities lead toward the maturation of RNA into more stable forms, which then become involved in transcription and translation. In the related Arabidopsis equivalent, loss of function of this protein is a lethal mutation. In ruminants, EXOSC9 is differentially expressed throughout the gut at different stages of development. EXOSC9 seems to be important in the degradation of histone mRNA and may be important in some downstream epigenetic effects.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ChIP Video Protocol
ChIP Webinar
ICC/IF Video Protocol

FAQs for Exosome Component 9 Antibody (NBP1-71702H) (0)

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Calculators

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Bioinformatics

Gene Symbol EXOSC9