EDNRB/Endothelin R Type B Antibody - Azide and BSA Free Summary
Immunogen
A synthetic peptide from the c-terminal of human EDNRB/Endothelin R Type B conjugated to an immunogenic carrier protein was used as the immunogen. The peptide is homologous in rat and mouse.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EDNRB
Purity
Ammonium sulfate precipitation
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WB. A concentration of 10-50 ug/ml is recommended. The optimal concentration should be determined by the end user. Although not confirmed, this antibody may be useful in IHC-Paraffin/Frozen. Use in Immunohistochemistry-Paraffin reported in scientific literature (PMID 25572612) The sample size is shipped in liquid form.
Publications
Read Publications using NBP1-30599 in the following applications:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Sterilized water
Preservative
No Preservative
Concentration
LYOPH
Purity
Ammonium sulfate precipitation
Reconstitution Instructions
Reconstitute 0.5 mg size in 0.5 ml of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability. Please note the 0.1 mg size is provided in reconstituted format.
Alternate Names for EDNRB/Endothelin R Type B Antibody - Azide and BSA Free
ABCDS
EDNRB
endothelin B receptor
Endothelin receptor non-selective type
endothelin receptor type B
ETB
ET-B
ETBR
ET-BR
ETRB
HSCR
HSCR2
WS4A
Background
Endothelin receptor type B (ETRB) is a G protein-coupled receptor that activates a phosphatidylinoitol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. A splice variant (SVR), differing in the intracellular C-terminal domain, has been described for this receptor. Both WT and the variant bind ET1. However, they exhibit different responses upon binding suggesting that these two variants are functionally distinct.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Kuczmarski AV Role of the Endothelin System in Vascular Dysfunction in Women Thesis 2021-01-01
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