DMPK Antibody (713931)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

DMPK (dystrophia myotonica protein kinase), also called DMK, MDPK or MT-PK (myotonin protein kinase) is an 80 kDa cytoplasmic protein of the ser/thr kinase superfamily (EC 2.7.11.1). The 639 amino acid (aa) human DMPK includes a protein kinase domain (aa 81-349), an AGC kinase C-terminal domain (aa 350-425) and a coiled-coil negative regulatory domain that mediates dimerization (aa 467-546). Within the region used as an immunogen, human DMPK shares 72% and 73% aa sequence identity with mouse and rat DMPK, respectively. This region is included within 12 isoforms that range in size from 530-634 aa. The most prominent, muscle-specific isoform phosphorylates phospholamban and is critical for cardiac contractility.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: NEGAR FIROOZI	WB	Human	01/09/2023	View Summary Application Western Blot Sample Tested 293T whole cell lysate,Hela whole cell lysate Species Human Lot CFNG0221031

Array MAB6967

• DMPK Antibodies
• DMPK Lysates
• DMPK Proteins