DDX3 Antibody

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. This gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog. Alternative splicing of this gene generates 2 transcript variants, which are divergent in the 3'UTR.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: KD, WB.

Showing Publications 1 - 2 of 2.

Publications using NB200-196	Applications	Species
Saikruang, W;Ang Yan Ping, L;Abe, H;Kasumba, DM;Kato, H;Fujita, T; The RNA helicase DDX3 promotes IFNB transcription via enhancing IRF-3/p300 holocomplex binding to the IFNB promoter Scientific reports [PMID: 35273248] (Mouse)		Mouse
Nguyen CN, Nguyen KVA, Eom S et al. Regulation of p21 expression for anti-apoptotic activity of DDX3 against sanguinarine-induced cell death on intrinsic pathway Phytomedicine 2019-09-23 [PMID: 31568920] (WB, KD, Human)	WB, KD	Human

Array NB200-196

• DDX3 Antibodies