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Cyr61/CCN1 Antibody [DyLight 594]

 
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Product Details

Summary
Reactivity Hu, Mu, RbSpecies Glossary
Applications WB, Simple Western, ICC/IF, IHC, B/N
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-356AF350
Alexa Fluor 405
NB100-356AF405
Alexa Fluor 488
NB100-356AF488
Alexa Fluor 532
NB100-356AF532
Alexa Fluor 594
NB100-356AF594
Alexa Fluor 647
NB100-356AF647
Alexa Fluor 700
NB100-356AF700
Alexa Fluor 750
NB100-356AF750
Allophycocyanin
NB100-356APC
Biotin
NB100-356B
CoraFluor 1
NB100-356CL1
DyLight 350
NB100-356UV
DyLight 405
NB100-356V
DyLight 488
NB100-356G
DyLight 550
NB100-356R
DyLight 650
NB100-356C
DyLight 680
NB100-356FR
DyLight 755
NB100-356IR
FITC
NB100-356F
HRP
NB100-356H
Janelia Fluor 525
NB100-356JF525
Janelia Fluor 549
NB100-356JF549
Janelia Fluor 585
NB100-356JF585
Janelia Fluor 635
NB100-356JF635
Janelia Fluor 646
NB100-356JF646
Janelia Fluor 669
NB100-356JF669
PE
NB100-356PE
PerCP
NB100-356PCP
Unconjugated
NB100-356
mFluor Violet 450 SE
NB100-356MFV450
mFluor Violet 500 SE
NB100-356MFV500
mFluor Violet 610 SE
NB100-356MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB100-356
BSA Free
NB100-356
BSA Free
NB100-356SS
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Cyr61/CCN1 Antibody [DyLight 594] Summary

Immunogen
A synthetic peptide made to the human CYR61 protein sequence (between residues 150-250). [UniProt# O00622]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CCN1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Block/Neutralize
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Rabbit reactivity reported in scientific literature (PMID: 22401280). Mouse reactivity reported in scientific literature (PMID: 27776183).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Cyr61/CCN1 Antibody [DyLight 594]

  • CCN family member 1
  • CCN1
  • CCN1IGF-binding protein 10
  • Cyr61
  • Cysteine-rich angiogenic inducer 61
  • cysteine-rich, angiogenic inducer, 61
  • GIG1
  • GIG1cysteine-rich heparin-binding protein 61
  • IBP-10
  • IGFBP-10
  • IGFBP10cysteine-rich, anigogenic inducer, 61
  • Insulin-like growth factor-binding protein 10
  • protein CYR61
  • Protein GIG1

Background

CYR61 (Cysteine-rich angiogenic inducer 61) is a 381 amino acid secreted protein. It promotes cell proliferation, chemotaxis, angiogenesis extracellular matrix formation and cell adhesion and this appears to make CYR61 play a role in wound healing in skin fibroblasts. CYR61 expression is induced by growth factors. It interacts with several integrins and with heparan sulfate proteoglycan. CYR61 may play a role in T-cell non-Hodgkin's disease, breast cancer, epithelial neoplasia, hepatocellular carcinoma, ischemia, gastric cancer, endometriosis, prostate carcinoma, prostatitis, prostate cancer, breast carcinoma, cardiomyopathy, melanoma and adenocarcinoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CCN1