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CXCR3 Antibody (868013) [Unconjugated]

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CHO Chinese hamster ovary cell line transfected with rat CXCR3 and eGFP was stained with either (A) Mouse Anti-Rat CXCR3 Monoclonal Antibody (Catalog # MAB8109) or (B) Mouse IgG2B Flow Cytometry Isotype Control (Catalog # MAB0041) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).
CHO Chinese hamster ovary cell line transfected with rat CXCR3 and eGFP was stained with either (A) Mouse Anti-Rat CXCR3 Monoclonal Antibody (Catalog # MAB8109) or (B) Mouse IgG2B Flow Cytometry Isotype Control (Catalog ...read more

Product Details

Summary
Reactivity RtSpecies Glossary
Applications Flow, CyTOF-ready
Clone
868013
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB8109U-100UG
Alexa Fluor 405
FAB8109V-100UG
Alexa Fluor 488
FAB8109G-100UG
Alexa Fluor 532
FAB8109X
Alexa Fluor 594
FAB8109T-100UG
Alexa Fluor 647
FAB8109R-100UG
Alexa Fluor 700
FAB8109N-100UG
Alexa Fluor 750
FAB8109S-100UG
Allophycocyanin
FAB8109A
Allophycocyanin
FAB8109A-100UG
Allophycocyanin/Cy7
FAB8109APCCY7
Biotin
FAB8109B
CoraFluor 1
FAB8109CL1
DyLight 350
FAB8109D
DyLight 405
FAB8109E
DyLight 488
FAB8109K
DyLight 550
FAB8109L
DyLight 594
FAB8109M
DyLight 650
FAB8109W
DyLight 680
FAB8109Y
DyLight 755
FAB8109Z
FITC
FAB8109F
HRP
FAB8109H
Janelia Fluor 525
FAB8109JF525
Janelia Fluor 549
FAB8109I
Janelia Fluor 646
FAB8109J
Janelia Fluor 669
FAB8109JF669
PE/Atto594
FAB8109PEATT594
PE/Cy5.5
FAB8109PECY55
PE/Cy7
FAB8109PECY7
PerCP
FAB8109C
Phycoerythrin
FAB8109P
mFluor Violet 450 SE
FAB8109MFV450
mFluor Violet 500 SE
FAB8109MFV500
mFluor Violet 610 SE
FAB8109MFV610
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
FAB8109A-100UG
Carrier Free
FAB8109P
Carrier Free
FAB8109A
Carrier Free
MAB8109-SP
Carrier Free
FAB8109V-100UG
Carrier Free
FAB8109U-100UG
Carrier Free
FAB8109T-100UG
Carrier Free
FAB8109S-100UG
Carrier Free
FAB8109R-100UG
Carrier Free
FAB8109N-100UG
Carrier Free
FAB8109G-100UG
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CXCR3 Antibody (868013) [Unconjugated] Summary

Immunogen
NS0 mouse myeloma cell line transfected with rat CXCR3
Accession # Q9J119
Specificity
Detects rat CXCR3 in ELISA. Stains rat CXCR3 transfected cells but not irrelevant transfectants by Flow Cytometry.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CXCR3
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CXCR3 Antibody (868013) [Unconjugated]

  • CD183 antigen
  • CD183
  • chemokine (C-X-C motif) receptor 3
  • chemokine (C-X-C) receptor 3
  • CKR-L2IP-10 receptor
  • CMKAR3
  • C-X-C chemokine receptor type 3
  • CXCR3
  • CXC-R3
  • CXCR-3
  • G protein-coupled receptor 9CD182
  • GPR9
  • GPR9Mig-R
  • Interferon-inducible protein 10 receptor
  • IP10 receptor
  • IP10-R
  • Mig receptor
  • MigR

Background

CXCR3, also known as CD183, is an approximately 41 kDa (predicted) 7-transmembrane spanning receptor for the chemokines CXCL9, CXCL10, and CXCL11. It is expressed on activated T cells, B cells, and NK cells during inflammation. It is additionally upregulated on solid tumor cells, tumor endothelium, and cancer stem cells. CXCR3 plays a role in leukocyte recruitment to sites of inflammation. It also contributes to Th1 biased responses during autoimune diseases rheumatoid arthritis, systemic erythematosis, and type 1 diabetes. Rat CXCR3 shares 86% and 96% amino acid sequence identity with human and mouse CXCR3, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CXCR3
Uniprot