Name: CXCL10/IP-10/CRG-2 Antibody [Unconjugated]
Brand: Novus Biologicals
SKU: AF-266-NA
Rating: 4.3 (3 reviews)

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	ELISA, IHC, B/N, CyTOF-ready, Flow, ICC/IF
Clonality	Polyclonal
Host	Goat
Conjugate	Unconjugated
Concentration	LYOPH

Catalog# & Conjugate	Size	Price
Biotin BAF266

Catalog# & Formulation	Size	Price
Carrier Free AF-266-SP

Conjugate	Catalog #	Availability	Size	Price
Biotin	BAF266

CXCL10/IP-10/CRG-2 Antibody [Unconjugated]

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CXCL10/IP-10/CRG-2 Antibody [Unconjugated] Summary

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Publications for CXCL10/IP-10/CRG-2 Antibody (AF-266-NA)(29)

Reviews for CXCL10/IP-10/CRG-2 Antibody (AF-266-NA) (3) 4.33

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Immunogen	E. coli-derived recombinant human CXCL10/IP-10/CRG-2 Val22-Pro98 Accession # P02778
Specificity	Detects human CXCL10/IP-10/CRG-2 in direct ELISAs and Western blots.
Source	N/A
Isotype	IgG
Clonality	Polyclonal
Host	Goat
Gene	CXCL10
Purity Statement	Antigen Affinity-purified
Endotoxin Note	<0.20 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.2 mg/mL in sterile PBS.

Publications using AF-266-NA	Applications	Species
Yiyan Ou, Ruiling Chen, Qiwei Qian, Nana Cui, Qi Miao, Ruqi Tang et al. The immunological characteristics of TSPAN1 expressing B cells in autoimmune hepatitis Frontiers in Immunology 2022-12-15 [PMID: 36591302]
JL Booth, ES Duggan, VI Patel, W Wu, DM Burian, DC Hutchings, VL White, KM Coggeshall, MG Dozmorov, JP Metcalf Gene expression profiling of primary human type I alveolar epithelial cells exposed to Bacillus anthracis spores reveals induction of neutrophil and monocyte chemokines Microb. Pathog., 2018-04-25;0(0):. 2018-04-25 [PMID: 29704667] (Neutralization, Human)	Neutralization	Human
S Urra, MC Fischer, JR Martínez, L Véliz, P Orellana, A Solar, K Bohmwald, A Kalergis, C Riedel, AH Corvalán, JC Roa, R Fuentealba, CJ Cáceres, M López-Last, A León, N Droppelman, HE González Differential expression profile of CXCR3 splicing variants is associated with thyroid neoplasia. Potential role in papillary thyroid carcinoma oncogenesis? Oncotarget, 2017-12-20;9(2):2445-2467. 2017-12-20 [PMID: 29416784] (IHC-P, Human)	IHC-P	Human
RS Dagur, W Wang, Y Cheng, E Makarov, M Ganesan, H Suemizu, CL Gebhart, S Gorantla, N Osna, LY Poluektova Human hepatocytes depletion in the presence of HIV-1 infection in dual reconstituted humanized mice Biol Open, 2018-02-13;0(0):. 2018-02-13 [PMID: 29361613] (IHC-P)	IHC-P
Bridgette D. Furman, Collin L. Kent, Janet L. Huebner, Virginia B. Kraus, Amy L. McNulty, Farshid Guilak et al. CXCL10 is upregulated in synovium and cartilage following articular fracture Journal of Orthopaedic Research 2017-11-20 [PMID: 28906016]
Jillian M. Richmond, Dinesh S. Bangari, Kingsley I. Essien, Sharif D. Currimbhoy, Joanna R. Groom, Amit G. Pandya et al. Keratinocyte-Derived Chemokines Orchestrate T-Cell Positioning in the Epidermis during Vitiligo and May Serve as Biomarkers of Disease Journal of Investigative Dermatology 2017-02-01 [PMID: 27686391]
Xinqi Wu, Anita Giobbie-Hurder, Xiaoyun Liao, Donald Lawrence, David McDermott, Jun Zhou et al. VEGF Neutralization Plus CTLA-4 Blockade Alters Soluble and Cellular Factors Associated with Enhancing Lymphocyte Infiltration and Humoral Recognition in Melanoma Cancer Immunology Research 2016-10-01 [PMID: 27549123]
Shang L, Duan L, Perkey KE et al. Epithelium-innate immune cell axis in mucosal responses to SIV Mucosal Immunol 7/20/2016 [PMID: 27435105]
CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata J Immunol, 2016-07-13;0(0):. 2016-07-13 [PMID: 27412416] (IHC-P, Human)	IHC-P	Human
M Liu, X Zeng, J Wang, Z Fu, J Wang, M Liu, D Ren, B Yu, L Zheng, X Hu, W Shi, J Xu Immunomodulation by mesenchymal stem cells in treating human autoimmune disease-associated lung fibrosis Stem Cell Res Ther, 2016-04-23;7(1):63. 2016-04-23 [PMID: 27107963] (Neutralization, Human)	Neutralization	Human
Shang L, Smith A, Duan L, Perkey K, Qu L, Wietgrefe S, Zupancic M, Southern P, Masek-Hammerman K, Reeves R, Johnson R, Haase A NK cell responses to simian immunodeficiency virus vaginal exposure in naive and vaccinated rhesus macaques. J Immunol, 2014-06-04;193(1):277-84. 2014-06-04 [PMID: 24899503] (IHC, Primate - Macaca mulatta (Rhesus Macaque))	IHC	Primate - Macaca mulatta (Rhesus Macaque)
Castriconi R, Dondero A, Bellora F, Moretta L, Castellano A, Locatelli F, Corrias M, Moretta A, Bottino C Neuroblastoma-derived TGF-beta1 modulates the chemokine receptor repertoire of human resting NK cells. J Immunol, 2013-04-10;190(10):5321-8. 2013-04-10 [PMID: 23576682] (Neutralization, Human)	Neutralization	Human
Ann E. Østvik, Atle V B Granlund, Marit Bugge, Nadra J. Nilsen, Sverre H. Torp, Helge L. Waldum et al. Enhanced expression of CXCL10 in inflammatory bowel disease: potential role of mucosal Toll-like receptor 3 stimulation Inflammatory Bowel Diseases 2013-02-01 [PMID: 22685032]
Sarkar SA, Lee CE, Victorino F, Nguyen TT, Walters JA, Burrack A, Eberlein J, Hildemann SK, Homann D Expression and regulation of chemokines in murine and human type 1 diabetes. Diabetes, 2011-12-30;61(2):436-46. 2011-12-30 [PMID: 22210319] (Flow Cytometry, Human)	Flow Cytometry	Human
Taghi Manshouri, Zeev Estrov, Alfonso Quintás-Cardama, Jan Burger, Ying Zhang, Ana Livun et al. Bone marrow stroma-secreted cytokines protect JAK2(V617F)-mutated cells from the effects of a JAK2 inhibitor Cancer Research 2011-06-01 [PMID: 21512135]
Jeffrey H. Ruth, Monica D. Arendt, M. Asif Amin, Salahuddin Ahmed, Hubert Marotte, Bradley J. Rabquer et al. Expression and function of CXCL16 in a novel model of gout Arthritis & Rheumatism 2010-06-03 [PMID: 20506383]
Shan M, Cheng HF, Song LZ Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema. Sci Transl Med, 2009-10-28;1(4):4ra10. 2009-10-28 [PMID: 20368170] (ICC, IHC-Fr, Human)	ICC, IHC-Fr	Human
Blanche Ka Ki Lo, Mei Yu, David Zloty, Bryce Cowan, Jerry Shapiro, Kevin John McElwee CXCR3/Ligands Are Significantly Involved in the Tumorigenesis of Basal Cell Carcinomas The American Journal of Pathology 2010-05-01 [PMID: 20228225]
Maingat F, Viappiani S, Zhu Y, Vivithanaporn P, Ellestad KK, Holden J, Silva C, Power C Regulation of lentivirus neurovirulence by lipopolysaccharide conditioning: suppression of CXCL10 in the brain by IL-10. J. Immunol., 2009-12-30;184(3):1566-74. 2009-12-30 [PMID: 20042580] (IHC-P, Western Blot, Feline, Human)	IHC-P, Western Blot	Feline, Human
Kim MJ, Romero R, Kim CJ, Tarca AL, Chhauy S, LaJeunesse C, Lee DC, Draghici S, Gotsch F, Kusanovic JP, Hassan SS, Kim JS Villitis of unknown etiology is associated with a distinct pattern of chemokine up-regulation in the feto-maternal and placental compartments: implications for conjoint maternal allograft rejection and maternal anti-fetal graft-versus-host disease. J. Immunol., 2009-03-15;182(6):3919-27. 2009-03-15 [PMID: 19265171] (IHC-Fr, Human)	IHC-Fr	Human
Okumura S, Yuki K, Kobayashi R, Okamura S, Ohmori K, Saito H, Ra C, Okayama Y Hyperexpression of NOD2 in intestinal mast cells of Crohn's disease patients: preferential expression of inflammatory cell-recruiting molecules via NOD2 in mast cells. Clin. Immunol., 2008-10-19;130(2):175-85. 2008-10-19 [PMID: 18938111] (IHC-Fr, Human)	IHC-Fr	Human
van Heteren JT, Rozenberg F, Aronica E, Troost D, Lebon P, Kuijpers TW Astrocytes produce interferon-alpha and CXCL10, but not IL-6 or CXCL8, in Aicardi-GoutiÃƒÂ¨res syndrome. Glia, 2008-04-01;56(5):568-78. 2008-04-01 [PMID: 18240301] (IHC-P, Human)	IHC-P	Human
Datta D, Flaxenburg JA, Laxmanan S, Geehan C, Grimm M, Waaga-Gasser AM, Briscoe DM, Pal S Ras-induced modulation of CXCL10 and its receptor splice variant CXCR3-B in MDA-MB-435 and MCF-7 cells: relevance for the development of human breast cancer. Cancer Res., 2006-10-01;66(19):9509-18. 2006-10-01 [PMID: 17018607] (IHC-Fr, Human)	IHC-Fr	Human
Meller S, Winterberg F, Gilliet M, Muller A, Lauceviciute I, Rieker J, Neumann NJ, Kubitza R, Gombert M, Bunemann E, Wiesner U, Franken-Kunkel P, Kanzler H, Dieu-Nosjean MC, Amara A, Ruzicka T, Lehmann P, Zlotnik A, Homey B Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus. Arthritis Rheum., 2005-05-01;52(5):1504-16. 2005-05-01 [PMID: 15880822] (IHC-Fr, Human)	IHC-Fr	Human
van Marle G, Henry S, Todoruk T, Sullivan A, Silva C, Rourke SB, Holden J, McArthur JC, Gill MJ, Power C Human immunodeficiency virus type 1 Nef protein mediates neural cell death: a neurotoxic role for IP-10. Virology, 2004-11-24;329(2):302-18. 2004-11-24 [PMID: 15518810] (ICC, IHC-P, Human)	ICC, IHC-P	Human
Ohshima K, Karube K, Kawano R, Tsuchiya T, Suefuji H, Yamaguchi T, Suzumiya J, Kikuchii M Classification of distinct subtypes of peripheral T-cell lymphoma unspecified, identified by chemokine and chemokine receptor expression: Analysis of prognosis. Int. J. Oncol., 2004-09-01;25(3):605-13. 2004-09-01 [PMID: 15289861] (IHC-P, Human)	IHC-P	Human
Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E, Noonan D, Albini A, Bernardi G, Mancardi GL, Battistini L, Uccelli A Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS. J. Leukoc. Biol., 2003-05-01;73(5):584-90. 2003-05-01 [PMID: 12714572] (Neutralization, Human)	Neutralization	Human
Keane MP, Donnelly SC, Belperio JA, Goodman RB, Dy M, Burdick MD, Fishbein MC, Strieter RM Imbalance in the expression of CXC chemokines correlates with bronchoalveolar lavage fluid angiogenic activity and procollagen levels in acute respiratory distress syndrome. J. Immunol., 2002-12-01;169(11):6515-21. 2002-12-01 [PMID: 12444162] (ELISA Development, IHC-P, Human)	ELISA Development, IHC-P	Human
Lauw FN, Dekkers PE, te Velde AA, Speelman P, Levi M, Kurimoto M, Hack CE, Van Deventer SJ, van der Poll T Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees. J. Infect. Dis., 1999-03-01;179(3):646-52. 1999-03-01 [PMID: 9952371] (ELISA Development, Primate - Pan troglodytes (Chimpanzee))	ELISA Development	Primate - Pan troglodytes (Chimpanzee)
Show All 29 Publications. Collapse Publications.

	Maximilian Haist 01/18/2023
Application:	IHC-P
Species:	Human

	Verified Customer 01/07/2015
Application:	IF
Species:	Human

	Verified Customer 01/07/2015
Application:	IHC-P
Species:	Human

Gene Symbol	CXCL10
Uniprot	P02778()