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CX3CL1/Fractalkine Antibody (81513) [Unconjugated]

 (14 Publications)
 (1 Review)
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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
81513
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB3651-SP
Carrier Free
MAB3651-500
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CX3CL1/Fractalkine Antibody (81513) [Unconjugated] Summary

Immunogen
NS0 and E. coli-derived recombinant human CX3CL1/Fractalkine Chemokine Domain
Gln25-Arg339 (Ser199Asn)
Accession # P78423
Specificity
Detects human CX3CL1/Fractalkine Chemokine Domain in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CX3CL1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 8-25 ug/mL
  • Western Blot 1 ug/mL
Reviewed Applications
Read 1 Review rated 5
using
MAB3651 in the following applications:
Publications
Read Publications using
MAB3651 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CX3CL1/Fractalkine Antibody (81513) [Unconjugated]

  • ABCD-3
  • C3Xkine
  • chemokine (C-X3-C motif) ligand 1
  • CX3C membrane-anchored chemokine
  • CX3CL1
  • CXC3
  • CXC3C
  • FKN
  • Fractalkine
  • Neurotactin
  • neurotactin)
  • NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine
  • NTTSmall-inducible cytokine D1
  • SCYD1C-X3-C motif chemokine 1
  • small inducible cytokine subfamily D (Cys-X3-Cys), member-1

Background

CX3CL1 is a type I membrane protein in which an extracellular chemokine domain possessing a unique C-X3-C cysteine motif is tethered on a long mucin-like stalk. It can also be released as a soluble molecule upon proteolysis at a membrane proximal site.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CX3CL1/Fractalkine
Antibody (81513) [Unc ...
MAB3651
CX3CL1/Fractalkine Antibody (81513) [Unconjugated]
Species: Hu
Applications: WB, IHC

Publications for CX3CL1/Fractalkine Antibody (MAB3651)(14)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 6 applications: Flow Cytometry, ICC, IHC, IHC-P, Neutralization, Western Blot.


Filter By Application
Flow Cytometry
(2)
ICC
(3)
IHC
(3)
IHC-P
(2)
Neutralization
(2)
Western Blot
(3)
All Applications
Filter By Species
Human
(10)
All Species
Showing Publications 1 - 10 of 14. Show All 14 Publications.
Publications using MAB3651 Applications Species
F Lunardi, DI Abbrescia, L Vedovelli, F Pezzuto, F Fortarezza, GM Comacchio, V Guzzardo, P Ferrigno, M Loy, C Giraudo, AS Fraia, E Faccioli, F Braccioni, E Cozzi, D Gregori, GM Verleden, F Calabrese, FP Schena, F Rea Molecular Profiling of Tissue Samples with Chronic Rejection from Patients with Chronic Lung Allograft Dysfunction: A Pilot Study in Cystic Fibrosis Patients Biomolecules, 2023-01-03;13(1):. 2023-01-03 [PMID: 36671482] (IHC, Human) IHC Human
Liu W, Danckwardt-Lilliestr�m N, Schrott-Fischer A et al. Distribution of Immune Cells Including Macrophages in the Human Cochlea Frontiers in Neurology 11/22/2021 [PMID: 34880828]
Liu W, Danckwardt-Lilliestr�m N, Schrott-Fischer A et al. Distribution of Immune Cells Including Macrophages in the Human Cochlea Frontiers in Neurology 2021-11-22 [PMID: 34880828]
MA Ostuni, P Hermand, E Saindoy, N Guillou, J Guellec, A Coens, C Hattab, E Desuzinges, A Jawhari, S Iatmanen-H, O Lequin, P Fuchs, JJ Lacapere, C Combadière, F Pincet, P Deterre CX3CL1 homo-oligomerization drives cell-to-cell adherence Sci Rep, 2020-06-03;10(1):9069. 2020-06-03 [PMID: 32494000] (Western Blot, Human) Western Blot Human
Liu W, Kampfe Nordstrom C, Danckwardt-Lilliestrom N, Rask-Andersen H, Human Inner Ear Immune Activity: A Super-Resolution Immunohistochemistry Study Front Neurol 7/10/2019 [PMID: 31354608]
Kampfe Nordstrom C, Danckwardt-Lilliestrom N et al. The Human Endolymphatic Sac and Inner Ear Immunity: Macrophage Interaction and Molecular Expression. Front Immunol 2/19/2019 [PMID: 30774637]
W Liu, M Molnar, C Garnham, H Benav, H Rask-Ander Macrophages in the Human Cochlea: Saviors or Predators-A Study Using Super-Resolution Immunohistochemistry Front Immunol, 2018-02-13;9(0):223. 2018-02-13 [PMID: 29487598] (IHC, Human) IHC Human
Suzuki F, Kubota T Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity. Arthritis Res. Ther., 2012-03-06;14(2):R48. 2012-03-06 [PMID: 22394569] (IHC-P, Human) IHC-P Human
Huang YW, Su P, Liu GY, Crow MR, Chaukos D, Yan H, Robinson LA Constitutive endocytosis of the chemokine CX3CL1 prevents its degradation by cell surface metalloproteases. J. Biol. Chem., 2009-09-01;284(43):29644-53. 2009-09-01 [PMID: 19723636] (ICC, Human) ICC Human
Hurst LA, Bunning RA, Couraud PO, Romero IA, Weksler BB, Sharrack B, Woodroofe MN Expression of ADAM-17, TIMP-3 and fractalkine in the human adult brain endothelial cell line, hCMEC/D3, following pro-inflammatory cytokine treatment. J. Neuroimmunol., 2009-03-25;210(1):108-12. 2009-03-25 [PMID: 19324423] (ICC, Human) ICC Human
Show All 14 Publications.

Review for CX3CL1/Fractalkine Antibody (MAB3651) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using MAB3651:
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IF
(1)
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Human
(1)
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Images Ratings Applications Species Date Details
Immunofluorescence CX3CL1/Fractalkine MAB3651
Enlarge 		5
reviewed by:
Gareth Healey
 IF Human 01/18/2016
View

Summary

ApplicationImmunofluorescence
Sample TestedHuman HEC1A cells
SpeciesHuman

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Immunofluorescence CX3CL1/Fractalkine MAB3651
Enlarge
 Gareth Healey
01/18/2016
Application: IF
Species: Human
read this review

Bioinformatics

Gene Symbol CX3CL1
Uniprot