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COP9 signalosome complex subunit 2 Antibody

Images

 
Western Blot: COP9 signalosome complex subunit 2 Antibody [NBP1-31481] - Sample (30 ug of whole cell lysate) A: A431 B: H1299 C: Hela 10% SDS PAGE TRIP15antibody, antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: COP9 signalosome complex subunit 2 Antibody [NBP1-31481] - Paraformaldehyde-fixed HeLa, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: COP9 signalosome complex subunit 2 Antibody [NBP1-31481] - COP9 antibody detects COP9 protein at cytoplasm and nucleus on mouse fore brain by immunohistochemical analysis. Sample: ...read more
Immunohistochemistry-Paraffin: COP9 signalosome complex subunit 2 Antibody [NBP1-31481] - Paraffin-embedded Mahlavu xenograft, using antibody at 1:100 dilution.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ch, Pm, Xp, ZeSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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COP9 signalosome complex subunit 2 Antibody Summary

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human COP9 signalosome complex subunit 2. The exact sequence is proprietary.
Localization
Cytoplasm, Nucleus
Predicted Species
Rat (100%), Porcine (100%), Bovine (100%), Zebrafish (92%), Chicken (100%), Xenopus (100%), Monkey (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
COPS2
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Xenopus laevis (100%), Xenopus Tropicalis (100%), Rhesus Monkey (100%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for COP9 signalosome complex subunit 2 Antibody

  • Alien homolog
  • ALIEN
  • COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)
  • COP9 signalosome complex subunit 2
  • CSN2JAB1-containing signalosome subunit 2
  • SGN2TR-interacting protein 15
  • Signalosome subunit 2
  • thyroid receptor interacting protein 15
  • Thyroid receptor-interacting protein 15
  • TRIP15TRIP-15

Background

TRIP15 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. TRIP15 is also involved in early stage of neuronal differentiation via its interaction with NIF3L1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol COPS2