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Complement Factor I Antibody

Images

 
Immunohistochemistry-Paraffin: Complement Factor I Antibody [NBP1-88268] - Staining of human fallopian tube shows moderate positivity in erythrocytes.
Immunohistochemistry-Paraffin: Complement Factor I Antibody [NBP1-88268] - Staining of human liver shows moderate positivity in erythrocytes.
Immunohistochemistry-Paraffin: Complement Factor I Antibody [NBP1-88268] - Staining of human kidney shows moderate positivity in plasma.
Immunohistochemistry-Paraffin: Complement Factor I Antibody [NBP1-88268] - Staining of human testis shows moderate positivity in plasma.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Complement Factor I Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: GCWILTAAHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISNCSKFYGNRFYEKEMECAGTYDG
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CFI
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Complement Factor I Recombinant Protein Antigen (NBP1-88268PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Complement Factor I Antibody

  • AHUS3
  • C3b Inactivator
  • C3B/C4B inactivator
  • C3BINA
  • C3b-inactivator
  • CFI
  • complement component I
  • complement control protein factor I
  • complement factor I heavy chain
  • Complement Factor I
  • EC 3.4.21
  • EC 3.4.21.45
  • FIC3b-INA
  • I factor (complement)
  • IF
  • KAF
  • Konglutinogen-activating factor
  • light chain of factor I

Background

Factor I is a plasma protein of molecular weight 88 kDa, consisting of two disulphide linked chains of 50 and 38 kDa. Factor I is a serine protease with a high degree of specificity for C3b and C4b. It has a requirement for protein cofactors for cleavage of these complement proteins, Factor H, CR1 or MCP are required for C3b cleavage and C4bp or CR1 for C4b cleavage.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CFI