Collagen IV Antibody [Biotin]

These antibodies are well suited to detect extracellular matrix proteins in normal as well as disease state tissues. Disruption of tissue organization is the hallmark of neoplasia. Malignant lesions can be distinguished from benign by examining the breakdown of basement membranes and loss of 3-dimensional architecture. Malignant cells are presumed to use matrix metalloproteases to degrade barriers created by the extracellular matrix which then allows metastasis to occur. Collagenases, stomelysins and gelatinases can collectively degrade all of the various components of the extracellular matrix, including fibrillar and non-fibrillar collagens and basement membrane glycoproteins.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 application: IHC-P.

Showing Publication 1 - 1 of 1.

Publication using NB120-6581	Applications	Species
Nikolaou S, Hadjikypri X, Ioannou G et al. Functional and phenotypic distinction of the first two trophoblast subdivisions and identification of the border between them during early postimplantation: A prerequisite for understanding early patterning during placentogenesis. Biochem Biophys Res Commun 2018-01-29 [PMID: 29305264] (IHC-P)	IHC-P

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Yves Heremans	IHC-P	Mouse	09/21/2015	View Summary Application Immunohistochemistry-Paraffin Sample Tested Mouse Pancreas Species Mouse

Array NB120-6581

• Collagen IV Antibodies
• Collagen IV ELISA Kits
• Collagen IV Proteins