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Coagulation Factor III/Tissue Factor Antibody (323519) [Phycoerythrin]

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Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody (Catalog # FAB3832A) and either (A) Mouse Anti-Human Coagulation Factor III/Tissue Factor PE-conjugated Monoclonal Antibody (Catalog # FAB23391P) or (B) Mouse IgG1Phycoerythrin Isotype Control (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins.
Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody (Catalog # FAB3832A) and either (A) Mouse Anti-Human Coagulation Factor III/Tissue Factor ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
323519
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB23391U-100UG
Alexa Fluor 405
FAB23391V-100UG
Alexa Fluor 488
FAB23391G
Alexa Fluor 532
FAB23391X
Alexa Fluor 594
FAB23391T-100UG
Alexa Fluor 647
FAB23391R-100UG
Alexa Fluor 700
FAB23391N-100UG
Alexa Fluor 750
FAB23391S-100UG
Allophycocyanin
FAB23391A
Allophycocyanin/Cy7
FAB23391APCCY7
Biotin
FAB23391B
CoraFluor 1
FAB23391CL1
DyLight 350
FAB23391D
DyLight 405
FAB23391E
DyLight 488
FAB23391K
DyLight 550
FAB23391L
DyLight 594
FAB23391M
DyLight 650
FAB23391W
DyLight 680
FAB23391Y
DyLight 755
FAB23391Z
FITC
FAB23391F
HRP
FAB23391H
Janelia Fluor 525
FAB23391JF525
Janelia Fluor 549
FAB23391I
Janelia Fluor 646
FAB23391J
Janelia Fluor 669
FAB23391JF669
PE/Atto594
FAB23391PEATT594
PE/Cy5.5
FAB23391PECY55
PE/Cy7
FAB23391PECY7
Unconjugated
MAB23391
mFluor Violet 450 SE
FAB23391MFV450
mFluor Violet 500 SE
FAB23391MFV500
mFluor Violet 610 SE
FAB23391MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB23391
Carrier Free
MAB23391
Carrier Free
FAB23391A
Carrier Free
FAB23391G
Carrier Free
MAB23391-SP
Carrier Free
FAB23391V-100UG
Carrier Free
FAB23391U-100UG
Carrier Free
FAB23391T-100UG
Carrier Free
FAB23391S-100UG
Carrier Free
FAB23391R-100UG
Carrier Free
FAB23391N-100UG
Novus Biologicals offers 100% Guarantee

Coagulation Factor III/Tissue Factor Antibody (323519) [Phycoerythrin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Coagulation Factor III
Gly34-Glu251
Accession # P13726
Specificity
Detects human Coagulation Factor III/Tissue Factor in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant mouse Coagulation Factor III/Tissue Factor is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
F3
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publication using
FAB23391P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Coagulation Factor III/Tissue Factor Antibody (323519) [Phycoerythrin]

  • CD142 antigen
  • CD142
  • coagulation factor III (thromboplastin, tissue factor)
  • Coagulation Factor III
  • F3
  • FLJ17960
  • TF
  • TFA
  • Thromboplastin
  • Tissue Factor

Background

Coagulation Factor III/Tissue Factor (TF), also known as Thromboplastin and CD142, is an integral membrane protein found in a variety of cell types. It functions as a protein cofactor/receptor of Coagulation Factor VII, which is synthesized in the liver and circulated in the plasma (1). Upon binding of TF, the inactive factor VII is rapidly converted into activated VIIa. The resulting 1:1 complex of VIIa and TF initiates the coagulation pathway and has also important coagulation-independent functions such as angiogenesis (2). Synthesized as a 295 amino acid precursor, TF consists of a signal peptide (residues 1-32) and the mature chain (residues 33-295). As a type I membrane protein, it contains a transmembrane region (residues 252-274) and a cytoplasmic tail (residues 275-295) (3-6).

  1. Morrissey, J.H. (2004) in Handbook of Proteolytic Enzymes. Barrett, A.J. et al. (ed) San Diego, Academic Press, p. 1659. 
  2. Versteeg, H.H. et al. (2003) Carcinogenesis 24:1009. 
  3. Scarpati, E.M. et al. (1987) Biochemistry 26:5234.
  4. Fisher, K.L. et al. (1987) Thromb. Res. 48:89.
  5. Morrissey, J.H. et al. (1987) Cell 50:129.
  6. Spicer, E.K. (1987) Proc. Natl. Acad. Sci. USA 84:5148.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Coagulation Factor III/Tissue Factor Antibody (FAB23391P)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


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FAQs for Coagulation Factor III/Tissue Factor Antibody (FAB23391P). (Showing 1 - 1 of 1 FAQ).

  1. Have you tested any of your anti-tissue factor antibodies against pig? I need one for western blot.
    • Unfortunately, none of our Tissue Factor antibodies have yet been tested with pig samples, so we cannot guarantee that any of them will work in pig. Here is a link to Tissue Factor antibodies that have been validated for use in Western blot. If you are interested in testing any of these antibodies against pig samples, you could become eligible for our Innovator's Reward program.

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Bioinformatics

Gene Symbol F3
Uniprot