Human TFPI Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Tissue Factor Pathway Inhibitor (TFPI) is a key regulator of the extrinsic coagulation pathway. It inhibits coagulation through the formation of a quaternary complex with Coagulation Factor X, Coagulation Factor III/Tissue Factor, and Coagulation Factor VII, thereby preventing the activation of Factor X. TFPI also exhibits anti-angiogenic and anti-metastatic effects. It is produced by vascular endothelial cells and circulates as a free molecule, on platelet surfaces, and in complex with LDL and HDL particles. Abnormal TFPI concentrations in the circulation are associated with thrombosis, disseminated intravascular coagulation, and sepsis. TFPI can enhance anti-thrombotic treatment in sepsis, inflammatory diseases, and cardiovascular diseases.

We have publications tested in 2 confirmed species: Human, Primate - Papio ursinus (Chacma baboon).

Showing Publications 1 - 10 of 12. Show All 12 Publications. Collapse Publications.

Publications using DTFP10	Applications	Species
Li, X;Song, X;Mahmood, DFD;Sim, MMS;Bidarian, SJ;Wood, JP; Activated protein C, protein S, and tissue factor pathway inhibitor cooperate to inhibit thrombin activation Thrombosis research 2023-08-23 [PMID: 37660436] (Human)		Human
Ghanbari, EP;Jakobs, K;Puccini, M;Reinshagen, L;Friebel, J;Haghikia, A;Kr�nkel, N;Landmesser, U;Rauch-Kr�hnert, U; The Role of NETosis and Complement Activation in COVID-19-Associated Coagulopathies Biomedicines 2023-05-05 [PMID: 37239041] (Human)		Human
VE Fiestas So, NR da Costa F, CF Dos Santos, G Corrêa, MDC Cipitelli, M Dornelas R, LJ de Souza, PV Damasco, RV da Cunha, FB Dos Santos, LM de Oliveir, EL de Azeredo Different Profiles of Cytokines, Chemokines and Coagulation Mediators Associated with Severity in Brazilian Patients Infected with Dengue Virus Viruses, 2021-09-08;13(9):. 2021-09-08 [PMID: 34578370] (Human)		Human
LE Landgrebe, CB Juhl, V Andersen, L Moitinho-S, C Bang, EM Bladbjerg Postprandial factor VII activation does not increase plasma concentrations of prothrombin fragment 1�+�2 in patients with morbid obesity Thromb. Res., 2020-09-01;196(0):260-267. 2020-09-01 [PMID: 32920297] (Human)		Human
S Chang, D Biltoft, A Skakkebæk, J Fedder, A Bojesen, MV Bor, CH Gravholt, AB Münster Testosterone treatment and association with thrombin generation and coagulation inhibition in Klinefelter syndrome: A cross-sectional study Thromb. Res., 2019-08-19;182(0):175-181. 2019-08-19 [PMID: 31505312] (Human)		Human
H Schöchl, M van Griens, S Heitmeier, V Laux, U Kipman, J Roodt, S Bahrami, H Redl Dual inhibition of thrombin and activated factor X attenuates disseminated intravascular coagulation and protects organ function in a baboon model of severe Gram-negative sepsis Crit Care, 2017-03-13;21(1):51. 2017-03-13 [PMID: 28288667] (Primate - Papio ursinus (Chacma baboon))		Primate - Papio ursinus (Chacma baboon)
E Leal de Az, VE Solórzano, DB de Oliveir, CF Marinho, LJ de Souza, RV da Cunha, PV Damasco, CF Kubelka, LM de-Oliveir Increased circulating procoagulant and anticoagulant factors as TF and TFPI according to severity or infecting serotypes in human dengue infection Microbes Infect, 2016-08-31;19(1):62-68. 2016-08-31 [PMID: 27592310] (Human)		Human
Annette Eyking MiR-205 and MiR-373 Are Associated with Aggressive Human Mucinous Colorectal Cancer PLoS ONE, 2016-06-06;11(6):e0156871. 2016-06-06 [PMID: 27271572] (Human)		Human
Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation Sci Rep, 2016-05-04;6(0):25171. 2016-05-04 [PMID: 27142573] (Human)		Human
The C-terminus of tissue factor pathway inhibitor alpha is required for its interaction with factors V and Va. J. Thromb. Haemost., 2012-09-01;10(9):1944-6. 2012-09-01 [PMID: 22738072] (Human)		Human
Girard TJ, Tuley E, Broze GJ TFPIbeta is the GPI-anchored TFPI isoform on human endothelial cells and placental microsomes. Blood, 2011-12-05;119(5):1256-62. 2011-12-05 [PMID: 22144186] (Human)		Human
Kentsis A, Bradwin G, Miller DT, Trenor CC Venous thrombosis associated with gene deletion of tissue factor pathway inhibitor. Am. J. Hematol., 2009-11-01;84(11):775-6. 2009-11-01 [PMID: 19806663] (Human)		Human
Show All 12 Publications. Collapse Publications.

Array DTFP10

• TFPI Antibodies
• TFPI Antibody Pairs
• TFPI Lysates
• TFPI Protein
• TFPI ELISAs
• TFPI Proteins and Enzymes