Claudin-1 Antibody Blocking Peptide Summary
Description |
A blocking peptide containing 20 amino acids near the carboxy terminus of human Claudin-1. Source: Synthetic (Accession #: CAG33419) |
Source |
Synthetic |
Protein/Peptide Type |
Antibody Blocking Peptide |
Gene |
CLDN1 |
Purity |
N/A |
Applications/Dilutions
Dilutions |
|
Application Notes |
This peptide is useful as a blocking peptide for NBP1-77036. For further blocking peptide related protocol, click here. |
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin. |
Preservative |
0.02% Sodium Azide |
Concentration |
0.2 mg/ml |
Purity |
N/A |
Alternate Names for Claudin-1 Antibody Blocking Peptide
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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