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CHMP2B Antibody (SR1463)

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Western Blot: CHMP2B Antibody (SR1463) [NBP3-22344] - Western blot analysis using NBP3-22344 in A431 cell lysate.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, ICC/IF, IP
Clone
SR1463
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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CHMP2B Antibody (SR1463) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human CHMP2B (Uniprot #: Q9UQN3)
Specificity
Detects endogenous levels of total CHMP2B
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
CHMP2B
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:50
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunoprecipitation 1:50
  • Western Blot 1:500-1:2000
Theoretical MW
28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for CHMP2B Antibody (SR1463)

  • charged multivesicular body protein 2b
  • CHMP2.5
  • CHMP2.5VPS2BVPS2-2
  • CHMP2B
  • chromatin modifying protein 2B
  • Chromatin-modifying protein 2b
  • DKFZP564O123
  • DMT1
  • hVps2-2
  • Vacuolar protein sorting-associated protein 2-2
  • vacuolar protein-sorting-associated protein 2-2
  • VPS2 homolog B
  • Vps2-2
  • VPS2B

Background

Component of the escrt-iii complex, which is required for multivesicular bodies (mvbs) formation and sorting of endosomal cargo proteins into mvbs. the mvb pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. the escrt-iii complex is probably involved in the concentration of mvb cargo. in case of infection, the hiv-1 virus takes advantage of the escrt-iii complex for budding and exocytic cargos of viral proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CHMP2B Antibody (NBP3-22344) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CHMP2B