CD90/Thy1 Antibody (G7) [FITC] Summary
Immunogen |
Mouse T cell hybridoma C6/G8 |
Marker |
Mesenchymal Cell Marker |
Specificity |
Mouse CD90 (Thy-1.1 & Thy-1.2 alloantigens/Thy-1 epitope region A); Mr 28-32 kDa |
Isotype |
IgG2c Kappa |
Clonality |
Monoclonal |
Host |
Rat |
Gene |
THY1 |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry
- In vitro assay
- Knockdown Validated
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Publications |
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Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Buffer |
PBS |
Preservative |
Sodium Azide |
Purity |
Protein A or G purified |
Notes
Conjugated forms should be protected from prolonged exposure to light.
Alternate Names for CD90/Thy1 Antibody (G7) [FITC]
Background
CD90/Thy-1, a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. (1-4) It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes and neurons of all mouse strains. (1,2) MAb G7 stimulates T-cell proliferation and IL-2 secretion, via signalling through the T-cell receptor/CD3 complex. (1,5-7) The MAb has also been reported to promote apoptosis of thymocytes and CTL clones,4,7 and to mediate adhesion of thymocytes to thymic stroma.8
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for CD90/Thy1 Antibody (NBP1-28032)(6)
Showing Publications 1 -
6 of 6.
Publications using NBP1-28032 |
Applications |
Species |
Matsumura M, Watanabe YY, Robinson PW et al. Underwater and surface behavior of homing juvenile northern elephant seals. The Journal of experimental biology 2011-06-02 [PMID: 21270312] |
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Hueber, AO, G Raposo, M Pierres, HT He. Thy-1 triggers mouse thymocyte apoptosis through a bcl-2-resistant mechanism J Exp Med 1994-03-01 [PMID: 7906706]
Details: This citation used the Biotin version of this antibody. |
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Gunter, K, T Malek, E Shevach. T cell-activating properties of an anti-Thy-1 monoclonal antibody, possible analogy to OKT3/Leu-4 J Exp Med 1984-03-01 [PMID: 6142077]
Details: This citation used the Biotin version of this antibody. |
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Tentori, L, DM Pardoll, JC Zunigaq et al. Proliferation and production of IL-2 and B cell stimulatory factor 1/IL-4 in early fetal thymocytes by activation through Thy-1 and CD3 J Immunol 1988-02-01 [PMID: 2893823]
Details: This citation used the Biotin version of this antibody. |
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Sugiyama, E, A Cantagrel, T Reno et al. Selection of T cell receptor expression mutants through the functionally linked Ly-6A Cell Immunol 1990-10-01 [PMID: 1976441]
Details: This citation used the Biotin version of this antibody. |
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Ucker, DS, J Meyers, PS Obermiller. Activation-driven T cell death II Quantitative differences alone distinguish stimuli triggering nontransformed T cell proliferation or death J Immunol 1992-09-01 [PMID: 1380534]
Details: This citation used the Biotin version of this antibody. |
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Product General Protocols
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FAQs for CD90/Thy1 Antibody (NBP1-28032). (Showing 1 - 1 of 1 FAQs).
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We are interested in CD90 antibodies that could react with dog, please let me know which products in your catalog you would recommend.
- I would recommend one of theses <a href="http://www.novusbio.com/productsearch/CD90%252FThy1#fq=common_name%3A%22CD90%2FThy1%22&fq=species%3A%22Canine%22" target="_self">CD90 antibodies</a>, as these have all been validated for use with dog/canine samples.