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CD47 Antibody (472603) [Phycoerythrin]

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Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD47 PE-conjugated Monoclonal Antibody (Catalog # FAB4670P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
472603
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

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CD47 Antibody (472603) [Phycoerythrin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human CD47
Gln19-Pro139
Accession # Q08722
Specificity
Detects human CD47. Stains human CD47 transfectants but not irrelevant transfectants.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD47
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Reviewed Applications
Read 1 Review rated 5
using
FAB4670P in the following application:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD47 Antibody (472603) [Phycoerythrin]

  • antigen identified by monoclonal 1D8
  • Antigenic surface determinant protein OA3
  • CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
  • CD47 antigen
  • CD47 glycoprotein
  • CD47 molecule
  • CD47
  • IAP
  • IAPintegrin associated protein
  • Integrin-associated protein
  • leukocyte surface antigen CD47
  • MER6
  • MER6integrin-associated signal transducer
  • OA3
  • Protein MER6
  • Rh-related antigen

Background

CD47, also known as integrin-associated protein, is a ubiquitous 50 kDa multipass transmembrane protein with a single IgV-like domain at its N-terminus. CD47 binding to SIRP alpha prevents the phagocytic engulfment of viable cells. Thrombospondin interaction with CD47 on T cells reduces T cell proliferation and inflammatory reactions. Alternate splicing generates isoforms with truncated cytoplasmic domains. Within the N-terminal ECD, human CD47 shares 63% aa sequence identity with mouse and rat CD47.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD47 Antibody (FAB4670P) (0)

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Review for CD47 Antibody (FAB4670P) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using FAB4670P:
Filter by Applications
Flow
(1)
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Human
(1)
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Images Ratings Applications Species Date Details
  5
reviewed by:
Verified Customer
Flow Human 05/10/2019
View

Summary

ApplicationFlow Cytometry
Sample TestedHuman breast cancer cell lines
SpeciesHuman
LotAARP0115111

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FAQs for CD47 Antibody (FAB4670P) (0)

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Verified Customer
05/10/2019
Application: Flow
Species: Human

Bioinformatics

Gene Symbol CD47
Uniprot