Reactivity | HuSpecies Glossary |
Applications | Flow |
Clone | 472603 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Phycoerythrin |
Immunogen | Mouse myeloma cell line NS0-derived recombinant human CD47 Gln19-Pro139 Accession # Q08722 |
Specificity | Detects human CD47. Stains human CD47 transfectants but not irrelevant transfectants. |
Source | N/A |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Mouse |
Gene | CD47 |
Purity Statement | Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Reviewed Applications |
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Storage | Protect from light. Do not freeze.
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Buffer | Supplied in a saline solution containing BSA and Sodium Azide. |
Preservative | Sodium Azide |
CD47, also known as integrin-associated protein, is a ubiquitous 50 kDa multipass transmembrane protein with a single IgV-like domain at its N-terminus. CD47 binding to SIRP alpha prevents the phagocytic engulfment of viable cells. Thrombospondin interaction with CD47 on T cells reduces T cell proliferation and inflammatory reactions. Alternate splicing generates isoforms with truncated cytoplasmic domains. Within the N-terminal ECD, human CD47 shares 63% aa sequence identity with mouse and rat CD47.
Images | Ratings | Applications | Species | Date | Details | ||||||||
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reviewed by:
Verified Customer |
Flow | Human | 05/10/2019 |
Summary
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Secondary Antibodies |
Isotype Controls |
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