Human CD41/CD61 ELISA Kit (Colorimetric) Summary
Description |
This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples. |
Standard Curve Range |
0.039 - 160 ng/mL (example only; lot dependent) |
Sensitivity |
0.013 ng/ml (example only; lot dependent) |
Assay Type |
Sandwich ELISA |
Inter-Assay |
CV% < 11.3% (example only; lot dependent) |
Intra-Assay |
CV% < 5.8% (example only; lot dependent) |
Spike Recovery |
87 - 115% (example only; lot dependent) |
Kit Type |
ELISA Kit (Colorimetric) |
Gene |
ITGA2B |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Storage of components varies. See protocol for specific instructions. |
Alternate Names for Human CD41/CD61 ELISA Kit (Colorimetric)
Background
Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are
guaranteed for 6 months from date of receipt.
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